REFRESH NATURE CREAM
US over-the-counter (OTC) label
Aux États-Unis, ces produits sont vendus comme médicaments en vente libre (OTC) : solaires, antitranspirants, antipelliculaires, dentifrices anticaries, produits contre l'acné ou protecteurs cutanés. L'étiquette distingue les ingrédients actifs et inactifs. Dans l'Union européenne, un produit à finalité cosmétique doit respecter le règlement (CE) n° 1223/2009. Un filtre ou un actif admis aux États-Unis peut ne pas être autorisé pour cet usage dans l'Union. La qualification dépend de la finalité : un désinfectant pour les mains peut relever des biocides et un traitement de l'acné des médicaments. Cette analyse applique les règles cosmétiques aux ingrédients, sans établir la conformité du produit fini. La formule vendue en Europe sous le même nom peut être différente.
openFDA: US OTC product labels, analysed under European cosmetic rules, retrieved 28 October 2026.
- Brand or trade name
- REFRESH NATURE CREAM
- Manufacturer
- GP INTERNATIONAL CORP.
- Label date
- 22 June 2022
Stated use in the United States
purpose Acne Control
Published active ingredients
Glycerin 5.0 % Skin Protection Xanthium Strumarium Fruit Extract 0.17% Antioxidant Cnidium Monnieri Fruit Extract 0.17% Anti Flammatory Angelica Acutiloba Root Extract 0.17% Skin lightening Citric Acid 0.01% Exfoliating Malic Acid 0.003% Exfoliating
Published inactive ingredients
Water, Butylene Glycol Hydrogenated Polydecene, Beeswax, Cetearyl Olivate, Methylpropanediol, Pentaerythrityl Tetraethylhexanoate, Ethylhexyl Palmitate, Cetyl Ethylhexanoate, Sorbitan Olivate, Stearic Acid, Rhus Semialata Gall Extract, Hexanediol, Hydrolyzed Collagen, Cetearyl Alcohol , Dimethicone, Sodium Acrylate, Sodium Acryloyldimethyl, Taurate, Copolymer,Palmitic Acid, Propanediol, Isohexadecane, Hydroxyacetophenone, Carbomer, Arginine, Limonia Acidissima Extract,Centella Asiatica Extract, Chlorphenesin, Ethylhexylglycerin, Polysorbate 80, Xanthan Gum,Fragrance,Benzyl Salicylate,Coumarin, Butylphenyl Methylpropional, Limonene, Linalool, Disodium EDTA,Sodium Lactate,Arachidic Acid,Citric Acid,Sodium PCA,Myristic Acid,Lactic Acid,Pyruvic Acid,Tartaric Acid,Alcohol,Polysorbate 20, Madecassoside
openFDA: US OTC product labels, analysed under European cosmetic rules, retrieved 28 October 2026.
Label in the official openFDA API. This is the label date; the formula may have changed. Compare with the packaging.
Cosmetic analysis in the European Union
1 ingredient prohibited in cosmetics in the European Union: Butylphenyl Methylpropional (since 1 March 2022). A product that contains it should no longer be sold in the Union. 5 ingredients allowed under conditions (maximum concentration, product types): some active ingredient concentrations are printed; the other conditions and the product's classification in the European Union remain to be checked. 52 names recognised out of 62.
Warning: 10 names out of 62 are not recognised (Skin Protection, Antioxidant, Anti Flammatory, Skin lightening, Exfoliating, Exfoliating, Sodium Acrylate, Sodium Acryloyldimethyl, Taurate, Copolymer): nothing below covers them.
- Pregnancy and breastfeeding : Prohibition or serious classification BUTYLPHENYL METHYLPROPIONAL
Glycerin 5.0 %, Skin Protection, Xanthium Strumarium Fruit Extract, Antioxidant, Cnidium Monnieri Fruit Extract, Anti Flammatory, Angelica Acutiloba Root Extract, Skin lightening, Citric Acid, Exfoliating, Malic Acid, Exfoliating, Water, Butylene Glycol, Hydrogenated Polydecene, Beeswax, Cetearyl Olivate, Methylpropanediol, Pentaerythrityl Tetraethylhexanoate, Ethylhexyl Palmitate, Cetyl Ethylhexanoate, Sorbitan Olivate, Stearic Acid, Rhus Semialata Gall Extract, Hexanediol, Hydrolyzed Collagen, Cetearyl Alcohol, Dimethicone, Sodium Acrylate, Sodium Acryloyldimethyl, Taurate, Copolymer, Palmitic Acid, Propanediol, Isohexadecane, Hydroxyacetophenone, Carbomer, Arginine, Limonia Acidissima Extract, Centella Asiatica Extract, Chlorphenesin, Ethylhexylglycerin, Polysorbate 80, Xanthan Gum, Fragrance, Benzyl Salicylate, Coumarin, Butylphenyl Methylpropional, Limonene, Linalool, Disodium EDTA, Sodium Lactate, Arachidic Acid, Citric Acid, Sodium PCA, Myristic Acid, Lactic Acid, Pyruvic Acid, Tartaric Acid, Alcohol, Polysorbate 20, Madecassoside
Who it concerns
For each group, the ingredients of the list that an official classification or rule mentions. Open an ingredient's page to read what the text says. A group with no name does not mean the ingredients were judged to have no effect for it.
Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.
Pregnancy and breastfeeding
- Prohibition or serious classification BUTYLPHENYL METHYLPROPIONALClassified under the CLP Regulation: reproductive toxicity, category 1B (Repr. 1B), a hazard to fertility (known or presumed hazard) and the unborn child (suspected hazard).
Skin, eyes and allergies
- Worth watching PARFUM“Parfum” stands for a mixture whose composition does not have to be detailed. Some allergenic substances must nevertheless be named separately in the ingredient list above 0.001% (leave-on product) or 0.01% (rinse-off product). The Regulation names them in 63 entries of its Annex III, for example Linalool, Limonene, Citronellol, Geraniol, Coumarin, Citral, Eugenol or Hexyl Cinnamal: if you are allergic to one of them, look for its name in the list.
- Worth watching BENZYL SALICYLATEClassified under the CLP Regulation: skin sensitisation, category 1B (Skin Sens. 1B). Allergen to declare: Annex III, entry 75, requires it to be named in the ingredient list above 0.001% in a leave-on product and 0.01% in a rinse-off product, so that allergic people can avoid it.
- Worth watching COUMARINAllergen to declare: Annex III, entry 77, requires it to be named in the ingredient list above 0.001% in a leave-on product and 0.01% in a rinse-off product, so that allergic people can avoid it.
- Worth watching LIMONENEClassified under the CLP Regulation: skin irritation, category 2 (Skin Irrit. 2); skin sensitisation, category 1 (Skin Sens. 1). Allergen to declare: Annex III, entry 88, requires it to be named in the ingredient list above 0.001% in a leave-on product and 0.01% in a rinse-off product, so that allergic people can avoid it.
- Worth watching LINALOOLClassified under the CLP Regulation: skin sensitisation, category 1B (Skin Sens. 1B). Allergen to declare: Annex III, entry 84, requires it to be named in the ingredient list above 0.001% in a leave-on product and 0.01% in a rinse-off product, so that allergic people can avoid it.
- For information CITRIC ACIDClassified under the CLP Regulation: eye irritation, category 2 (Eye Irrit. 2). This classification describes the pure substance; in a finished product it is far more diluted.
- For information ETHYLHEXYLGLYCERINClassified under the CLP Regulation: serious eye damage, category 1 (Eye Dam. 1). This classification describes the pure substance; in a finished product it is far more diluted.
Environment
- Worth watching LIMONENEClassified under the CLP Regulation: hazardous to the aquatic environment, short term, category 1 (Aquatic Acute 1); hazardous to the aquatic environment, long term, category 1 (Aquatic Chronic 1).
- For information ETHYLHEXYLGLYCERINClassified under the CLP Regulation: hazardous to the aquatic environment, long term, category 3 (Aquatic Chronic 3).
No official text covers the recognised ingredients for: babies and children, read on the label.
For a question about your own situation (pregnancy, child, allergy), show this list to your doctor, midwife or pharmacist: we cannot say whether this product suits you.
Selling elsewhere
Ingredients of this list that are prohibited, prohibited in some cases or subject to conditions in the other countries whose rules we record (nothing changes for sale in France). Absence is not approval: several countries only allow the preservatives, UV filters and colorants on their lists, and the function of an ingredient in the product is not known. What is covered for each country.
| Country | Prohibited | Prohibited in some cases | Subject to conditions |
|---|---|---|---|
| United Kingdom | Butylphenyl Methylpropional | - | Chlorphenesin, Benzyl Salicylate, Coumarin, Limonene, Linalool |
| California | - | Butylphenyl Methylpropional (from 1 January 2027) | - |
| Canada | - | - | Glycerin 5.0 %, Citric Acid, Hydrolyzed Collagen, Lactic Acid, Tartaric Acid |
| Japan | - | - | Chlorphenesin |
| South Korea | - | Limonene | Chlorphenesin, Butylphenyl Methylpropional |
| ASEAN | Butylphenyl Methylpropional | - | Chlorphenesin |
| Taiwan | - | - | Chlorphenesin |
| Brazil | Butylphenyl Methylpropional | - | Chlorphenesin |
No prohibition or condition found in the recorded lists for: United States (federal), Washington State, China, Australia.
Ingredient by ingredient
The line under each name gives its rule in the European Union (legend below). Click a name for its page.
Hover over or tap a badge for its meaning.
Classified hazard (cancer, DNA, reproduction): Carcinogenic, mutagenic or toxic for reproduction under the CLPEU regulation that classifies chemicals by their hazards (EC No 1272/2008). Regulation, or identified endocrine disruptor. Irritation, allergy and environment: see “Who it concerns”.
| On the label | Glossary name | Rule in the European Union | Classified hazard (cancer, DNA, reproduction) |
|---|---|---|---|
| Glycerin 5.0 % | GLYCERIN | No specific rule in the Cosmetics Regulation | none |
| Skin Protection | not recognised | Name not recognised in the European glossary | unknown |
| Xanthium Strumarium Fruit Extract | XANTHIUM STRUMARIUM FRUIT EXTRACT Certainty medium: name found in a list printed without commas | No specific rule in the Cosmetics Regulation | none |
| Antioxidant | not recognised | Name not recognised in the European glossary | unknown |
| Cnidium Monnieri Fruit Extract | CNIDIUM MONNIERI FRUIT EXTRACT Certainty medium: name found in a list printed without commas | No specific rule in the Cosmetics Regulation | none |
| Anti Flammatory | not recognised | Name not recognised in the European glossary | unknown |
| Angelica Acutiloba Root Extract | ANGELICA ACUTILOBA ROOT EXTRACT Certainty medium: name found in a list printed without commas | No specific rule in the Cosmetics Regulation | none |
| Skin lightening | not recognised | Name not recognised in the European glossary | unknown |
| Citric Acid | CITRIC ACID Certainty medium: name found in a list printed without commas | Entry for a mixture with the same CAS number (Annex V) | none |
| Exfoliating | not recognised | Name not recognised in the European glossary | unknown |
| Malic Acid | MALIC ACID Certainty medium: name found in a list printed without commas | No specific rule in the Cosmetics Regulation | none |
| Exfoliating | not recognised | Name not recognised in the European glossary | unknown |
| Water | WATER | No specific rule in the Cosmetics Regulation | none |
| Butylene Glycol | BUTYLENE GLYCOL Certainty medium: name found in a list printed without commas | No specific rule in the Cosmetics Regulation | none |
| Hydrogenated Polydecene | HYDROGENATED POLYDECENE Certainty medium: name found in a list printed without commas | No specific rule in the Cosmetics Regulation | none |
| Beeswax | BEESWAX | No specific rule in the Cosmetics Regulation | none |
| Cetearyl Olivate | CETEARYL OLIVATE | No specific rule in the Cosmetics Regulation | none |
| Methylpropanediol | METHYLPROPANEDIOL | No specific rule in the Cosmetics Regulation | none |
| Pentaerythrityl Tetraethylhexanoate | PENTAERYTHRITYL TETRAETHYLHEXANOATE | No specific rule in the Cosmetics Regulation | none |
| Ethylhexyl Palmitate | ETHYLHEXYL PALMITATE | No specific rule in the Cosmetics Regulation | none |
| Cetyl Ethylhexanoate | CETYL ETHYLHEXANOATE | No specific rule in the Cosmetics Regulation | none |
| Sorbitan Olivate | SORBITAN OLIVATE | No specific rule in the Cosmetics Regulation | none |
| Stearic Acid | STEARIC ACID | No specific rule in the Cosmetics Regulation | none |
| Rhus Semialata Gall Extract | RHUS SEMIALATA GALL EXTRACT | No specific rule in the Cosmetics Regulation | none |
| Hexanediol | HEXANEDIOL | No specific rule in the Cosmetics Regulation | none |
| Hydrolyzed Collagen | HYDROLYZED COLLAGEN | No specific rule in the Cosmetics Regulation | none |
| Cetearyl Alcohol | CETEARYL ALCOHOL | No specific rule in the Cosmetics Regulation | none |
| Dimethicone | DIMETHICONE | No specific rule in the Cosmetics Regulation | none |
| Sodium Acrylate | not recognised | Name not recognised in the European glossary | unknown |
| Sodium Acryloyldimethyl | not recognised | Name not recognised in the European glossary | unknown |
| Taurate | not recognised | Name not recognised in the European glossary | unknown |
| Copolymer | not recognised | Name not recognised in the European glossary | unknown |
| Palmitic Acid | PALMITIC ACID | No specific rule in the Cosmetics Regulation | none |
| Propanediol | PROPANEDIOL | No specific rule in the Cosmetics Regulation | none |
| Isohexadecane | ISOHEXADECANE | No specific rule in the Cosmetics Regulation | none |
| Hydroxyacetophenone | HYDROXYACETOPHENONE | No specific rule in the Cosmetics Regulation | none |
| Carbomer | CARBOMER | No specific rule in the Cosmetics Regulation | none |
| Arginine | ARGININE | No specific rule in the Cosmetics Regulation | none |
| Limonia Acidissima Extract | LIMONIA ACIDISSIMA EXTRACT | No specific rule in the Cosmetics Regulation | none |
| Centella Asiatica Extract | CENTELLA ASIATICA EXTRACT | No specific rule in the Cosmetics Regulation | none |
| Chlorphenesin | CHLORPHENESIN | Preservative allowed under conditions (Annex V) Annex V, entry 50: maximum concentration: 0.3% | none |
| Ethylhexylglycerin | ETHYLHEXYLGLYCERIN | No specific rule in the Cosmetics Regulation | none |
| Polysorbate 80 | POLYSORBATE 80 | No specific rule in the Cosmetics Regulation | none |
| Xanthan Gum | XANTHAN GUM | No specific rule in the Cosmetics Regulation | none |
| Fragrance | PARFUM Certainty certain: checked synonym | No specific rule in the Cosmetics Regulation | none |
| Benzyl Salicylate | BENZYL SALICYLATE | Allowed with restrictions (Annex III) Annex III, entry 75: products: (a) Fragrance products (hydroalcoholic and non-hydroalcoholic, spray and non-spray) (b) Rinse-off skin and hair products (except shower gel/bath products) (c) Shower gel/bath products (d) Leave-on skin and hair products (non-spray/non-aerosol) (except body lotion) (e) Leave-on hair products (spray/aerosol) (f) Body lotion (g) Face make-up and make-up remover products (h) Oral products (i) Deodorant products (spray/aerosol); maximum concentration: (a) 4% (b) 0.5% (c) 1.3% (d) 0.5% (e) 0.5% (f) 0.7% (g) 0.2% (h) 0.004% (i) 0.91% | none |
| Coumarin | COUMARIN | Allowed with restrictions (Annex III) | none |
| Butylphenyl Methylpropional | BUTYLPHENYL METHYLPROPIONAL | Prohibited in cosmetics (Annex II) | Toxic for reproduction: presumed effect (category 1B, CLP classification) |
| Limonene | LIMONENE | Allowed with restrictions (Annex III) | none |
| Linalool | LINALOOL | Allowed with restrictions (Annex III) | none |
| Disodium EDTA | DISODIUM EDTA | No specific rule in the Cosmetics Regulation | none |
| Sodium Lactate | SODIUM LACTATE | No specific rule in the Cosmetics Regulation | none |
| Arachidic Acid | ARACHIDIC ACID | No specific rule in the Cosmetics Regulation | none |
| Citric Acid | CITRIC ACID | Entry for a mixture with the same CAS number (Annex V) | none |
| Sodium PCA | SODIUM PCA | No specific rule in the Cosmetics Regulation | none |
| Myristic Acid | MYRISTIC ACID | No specific rule in the Cosmetics Regulation | none |
| Lactic Acid | LACTIC ACID | No specific rule in the Cosmetics Regulation | none |
| Pyruvic Acid | PYRUVIC ACID | No specific rule in the Cosmetics Regulation | none |
| Tartaric Acid | TARTARIC ACID | No specific rule in the Cosmetics Regulation | none |
| Alcohol | ALCOHOL | No specific rule in the Cosmetics Regulation | none |
| Polysorbate 20 | POLYSORBATE 20 | No specific rule in the Cosmetics Regulation | none |
| Madecassoside | MADECASSOSIDE | No specific rule in the Cosmetics Regulation | none |
List in the official revision dated (register: openFDA: US OTC product labels, analysed under European cosmetic rules).
List recorded in 2022. Photograph the packaging to check whether it has changed. Photograph the packaging