Compoatlas

CAPTAN

Official label name (INCI name, EU glossary of cosmetic ingredient names), No 5443

CAPTAN: Prohibited in cosmetics (Annex II, entry 370), under Regulation (EC) No 1223/2009.

In plain words

What it is used for

Functions declared by manufacturers:

Antimicrobial: helps control the growth of micro-organisms on the skin.

What the rules say

It is prohibited to use it in a cosmetic product sold in the European Union, whatever the dose. If it appears on the ingredient list of a recent product, this needs checking: the record may be old or wrong, or the product intended for another market.

Hazard and risk

The CLP Regulation classifies this substance as carcinogenic, category 2 (suspected effect, without enough evidence for a higher category).

This classification describes what the substance can cause (a hazard), not what happens when using a product (a risk): the risk depends on the dose, the form and the route of exposure (skin, inhalation, ingestion).

Already prohibited in cosmetics (Annex II).

The text of the annexes

Prohibited in cosmetics

CosIng links the name CAPTAN to this Annex II entry.

Entry
Annex II, No 370
Substance
captan (ISO); 1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide
CAS
133-06-2
EC
205-087-0
CMR
Carcinogenic Cat. 2()
Dates in the act (10)
  • Entry into force on 11 January 2010
  • Application from 1 December 2010
    It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
  • Entry into force on 1 December 2010
  • Condition applicable from 11 January 2012
    As from 11 January 2012, by way of derogation from Directive 76/768/EEC, notification carried out in accordance with Article 13 of this Regulation shall be considered to comply with Article 7(3) and Article 7a(4) of that Directive
  • Application from 11 January 2013
    July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
  • Entry into force on 11 January 2013
  • Application from 11 July 2013
    It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall appl
  • Entry into force on 11 July 2013
  • Placing on the market before 11 July 2013
    Article 39 Transitional provisions By way of derogation from Directive 76/768/EEC, cosmetic products which comply with this Regulation may be placed on the market before 11 July 2013.
  • Placing on the market from 11 July 2013
    As from 11 July 2013, a distributor who makes available in a Member State a cosmetic product already placed on the market in another Member State and translates, on his own initiative, any element of the labelling of that product in order to comply with national law, shall submit, by electronic means, the following info

Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.

Identity

CosIng identifier
84500
CAS (according to CosIng)
133-06-2
EC (according to CosIng)
205-087-0
Declared functions
Antimicrobial

Classified hazard (CLP Regulation)

A classification describes an intrinsic hazard, not a risk: the risk depends on the dose, the form and the exposure.

captan (ISO);1,2,3,6-tetrahydro-N-(trichloromethylthio)phthalimide

CMR Carc. 2

Hazard classes
Carc. 2
Acute Tox. 3 *
Eye Dam. 1
Skin Sens. 1
Aquatic Acute 1
Hazard statements
H351 H331 H318 H317 H400

Already prohibited in cosmetics (Annex II).

Elsewhere in the world

Information on other jurisdictions. What is covered, and what is not yet.

United Kingdom (Great Britain)

  • Prohibited in cosmetics (Annex II)

Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

South Korea

  • Prohibited: N-[(트리클로로메칠)치오]-4-사이클로헥센-1,2-디카르복시미드(캡탄)

    별표 1 (prohibited substances), entry 865, page 44.

China

  • Prohibited: N-（三氯甲基硫代）-4-环己烯-1,2-联羧酰胺（克霉丹） (N-（trichloromethylthio）-4-cyclohexene-1,2-dicarboximide （captan-ISO） （CAS No. 133-06-2）)

    表1 化妆品禁用原料目录 (prohibited substances, 2021年第74号), entry 928, page 附件2 (.doc) table row 928 ; TID reprint p.36.

Brazil

  • Prohibited: N - (triclorometiltio) - 4 - ciclohexeno - 1, 2 - dicarboximida (Captana - ISO)

    RDC 529/2021, Anexo (prohibited substances), entry 370, page 14. Conditions (source text, in Portuguese): N° UE: 370

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.