DIHYDROXYINDOLINE (leukoaminochrome)
Official label name (INCI name, EU glossary of cosmetic ingredient names), No 8735
- Allowed with restrictions (Annex III)
DIHYDROXYINDOLINE (leukoaminochrome): Allowed with restrictions, maximum 2.0% in the ready-for-use preparation, only in: Hair dye substance in non-oxidative hair dye products (Annex III, entry 204), under Regulation (EC) No 1223/2009.
In plain words
What it is used for
Functions declared by manufacturers:
Hair dyeing: colours hair.
What the rules say
Allowed, with restrictions: Annex III sets a maximum concentration, the product types allowed and a warning to be printed on the packaging. Ingredient lists do not give quantities, so the concentration cannot be checked on the label; the warning can.
The text of the annexes
Allowed with restrictions
- Product type
- Hair dye substance in non-oxidative hair dye products
- Maximum concentration
- 2.0%
- Warning to print
- - Can cause allergic reaction - You have ever experienced any reaction afther colouring your hair - You have experienced a reaction to a temporary 'black henna' tattoo in the past
- Entry
- Annex III, No 204
- Substance
- 2,3-Dihydro-1H-indole-5,6-diol and its hydrobromide salt (see note 17).
- Glossary names
- DIHYDROXYINDOLINE
- CAS
- 29539-03-5 - 138937-28-7
- EC
- - - 421-170-6
Dates in the act (3)
- Entry into force on 15 May 2013
- Application from 11 July 2013
It shall apply from 11 July 2013.
- Entry into force on 11 July 2013
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Elsewhere in the world
Information on other jurisdictions. What is covered, and what is not yet.
United Kingdom (Great Britain)
- Allowed with restrictions (Annex III)
Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
South Korea
- Prohibited: 2,3-디하이드로-1H-인돌-5,6-디올 (디하이드록시인돌린) 및 그 하이드로브로마이드염 (디하이드록시인돌린 하이드로브롬마이드)
별표 1 (prohibited substances), entry 203, page 11.
Conditions, source text, in Korean
화학물질명: 디하이드록시인돌린 (CAS No. 29539-03-5) | 화학물질명: 디하이드록시인돌린하이드로브로마이드 (CAS No. 138937-28-7) | ※ 유의사항 2: 1) 표시는 [별표 2] 염모제 성분에서 정한 기준에 적합한 경우는 제외한다.
- Restricted: 2,3-디하이드로-1H-인돌-5,6-디올(디하이드록시인돌린) 및 그 하이드로브로마이드염
별표 2, 염모제 성분 (hair colorants), entry 49, page 21. Limit: 비산화염모제에 2.0%.
Conditions, source text, in Korean
비고: 기타제품에는 사용금지 | 화학물질명: 디하이드록시인돌린 (CAS No. 29539-03-5) | 화학물질명: 디하이드록시인돌린 하이드로브로마이드 (CAS No. 138937-28-7)
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.