Compoatlas

NONOXYNOL-100

Official label name (INCI name, EU glossary of cosmetic ingredient names), No 17558

NONOXYNOL-100: no specific rule of the EU Cosmetics Regulation names it. It is neither prohibited nor restricted there, and it is on none of its lists of colorants, preservatives or UV filters. Annexes of the Regulation consulted on 21 October 2026.

Who it concerns

What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.

  • Pregnancy and breastfeeding

    No official classification covers reproduction, the unborn child's development or breastfeeding for this substance.

  • Babies and children

    The Cosmetics Regulation sets no age-related condition for this ingredient.

  • Skin, eyes and allergies

    No official classification for sensitisation, irritation or eye damage, and no obligation to label it as an allergen.

  • Environment

    Classified under the CLP Regulation: hazardous to the aquatic environment, short term, category 1 (Aquatic Acute 1); hazardous to the aquatic environment, long term, category 1 (Aquatic Chronic 1).

    ECHA has included it in the Candidate List as an endocrine disruptor for the environment.

In plain words

What it is used for

Functions declared by manufacturers:

Cleansing (surfactant): helps to keep the body surface clean.

What the rules say

No EU rule targets this ingredient specifically. It remains subject to the general rule: every product must undergo a safety assessment before it is sold (Article 10 of Regulation (EC) No 1223/2009), under the manufacturer's responsibility.

Hazard and risk

The European Union has identified it as an endocrine disruptor: a substance that alters the functioning of the hormonal system and causes adverse effects. This alone does not prohibit it in cosmetics: a legal text must add it to the annexes.

The text of the annexes

No specific rule of the EU Cosmetics Regulation names this ingredient: it is on none of its lists (prohibited, restricted, colorants, preservatives, UV filters). It may be used under the responsibility of the manufacturer, who must ensure the product is safe.

Identity

CosIng identifier
105192
CAS (according to CosIng)
26027-38-3, 37205-87-1, 68412-54-4, 9016-45-9
Declared functions
Surfactant: cleansing

CosIng cites 4 CAS numbers for this name: it covers several substances.

Classified hazard (CLP Regulation)

The harmonised classification is the one set by the European Union for the whole Union. H codes refer to the hazard statements of Annex III of Regulation (EC) No 1272/2008.

nonylphenol, branched and linear, ethoxylated (with average molecular weight ≤ 1 540 g/mol) [includes ortho-, meta-, para- isomers or any combination thereof]

Neither carcinogenic, mutagenic nor toxic for reproduction under the harmonised classification

Hazard classes
Hazardous to the aquatic environment, short term, category 1 (Aquatic Acute 1)
Hazardous to the aquatic environment, long term, category 1 (Aquatic Chronic 1)
Hazard statements
H400 H410

Endocrine disruptor

These lists record an evaluation, not a prohibition: in cosmetics, a substance identified as an endocrine disruptor is prohibited only if a legal text adds it to the annexes.

  • Identified as an endocrine disruptor at EU level

Recorded evaluations

  • Candidate list, REACH, 2013 (environment)

Elsewhere in the world

Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.

United Kingdom (Great Britain)

  • No specific rule in the Cosmetics Regulation

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.