TETRABROMOPHENOL BLUE
Official label name (INCI name, EU glossary of cosmetic ingredient names), No 28520
- Allowed with restrictions (Annex III)
TETRABROMOPHENOL BLUE: Allowed with restrictions, with limits depending on the product type (Annex III, entry 319), under Regulation (EC) No 1223/2009.
In plain words
What it is used for
Functions declared by manufacturers:
Hair dyeing: colours hair.
What the rules say
Allowed, with restrictions: Annex III sets a maximum concentration, the product types allowed and a warning to be printed on the packaging. Ingredient lists do not give quantities, so the concentration cannot be checked on the label; the warning can.
The text of the annexes
Allowed with restrictions
| Product type | Maximum concentration | Other conditions | Warning to print |
|---|---|---|---|
| (a) Hair dye substance in oxidative hair dye products | not set | As from 3 June 2021, after mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,2 % (calculated as free base). | As from 3 December 2021, to be printed on the label: The mixing ratio. ‘Image 5 Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary “black henna” tattoo in the past.’ |
| (b) Hair dye substance in non-oxidative hair dye products | As from 3 June 2021: 0,2 % | not set | not set |
- Entry
- Annex III, No 319
- Substance
- Phenol, 4,4'-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-
- Glossary names
- TETRABROMOPHENOL BLUE
- CAS
- 4430-25-5
- EC
- 224-622-9
Dates in the act (5)
- Entry into force on 3 December 2020
- Condition applicable from 3 June 2021
As from 3 June 2021: 0,5 % Methanesulfonates impurities, in particular ethyl methanesulfonate shall not be present
- Placing on the market from 3 June 2021
As from 3 June 2021: 25 %’ (*1) From 3 September 2021 hair and eyelash dye products containing those substances shall not be placed on the Union market
- Condition applicable from 3 December 2021
As from 3 December 2021, to be printed on the label: The mixing ratio
- Making available from 3 June 2022
From 3 June 2022 hair and eyelash dye products containing those substances shall not be made available on the Union market
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Identity
- CosIng identifier
- 60227
- CAS (according to CosIng)
- 4430-25-5
- EC (according to CosIng)
- 224-622-9
- Declared functions
- Hair dyeing
- Wikidata
- Q27288730
- PubChem
- 78159
- ECHA InfoCard
- 100.022.385
- InChIKey
- QPMIVFWZGPTDPN-UHFFFAOYSA-N
Elsewhere in the world
Information on other jurisdictions. What is covered, and what is not yet.
United Kingdom (Great Britain)
- Allowed with restrictions (Annex III)
Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.