TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE (2,4,6-trimethylbenzoyl diphenylphosphine oxide)
Official label name (INCIInternational name of cosmetic ingredients: the one printed on the pack. name, EU glossary of cosmetic ingredient names), No 29270
- Prohibited in cosmetics (Annex II)
TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE (2,4,6-trimethylbenzoyl diphenylphosphine oxide): Prohibited in cosmetics (Annex II, entry 1731), under Regulation (EC) No 1223/2009. Annexes of the Regulation consulted on 23 October 2026.
Who it concerns
This ingredient is prohibited in cosmetics in the European Union: what follows describes its hazards, not a permitted use.
What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.
Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.
Pregnancy and breastfeeding
Prohibited in cosmetics in the European Union for everyone, whatever the age or situation: no specific condition is therefore needed for this group.
Babies and children
Prohibited in cosmetics in the European Union for everyone, whatever the age or situation: no specific condition is therefore needed for this group.
Skin, eyes and allergies
No harmonised classification for sensitisation, irritation or eye damage, and no obligation to label it as an allergen.
Environment
No harmonised classification as hazardous to the aquatic environment, and it is not on ECHAEuropean Chemicals Agency.'s Candidate List as an endocrine disruptor for the environment.
Read on the label
The Cosmetics Regulation requires no warning to be printed for this ingredient.
In plain words
What it is used for
Functions declared by manufacturers:
Nail sculpting.
Functions declared in the CosIngThe European Commission's database of cosmetic ingredients. inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.
Definitions of functions (decision repealed on 8 May 2020, cited for information). Decision 2006/257/EC, inventory of cosmetic ingredients (definitions of functions), retrieved 22 October 2026.
What the rules say
It is prohibited to use it in a cosmetic product sold in the European Union, whatever the dose. If it appears on the ingredient list of a recent product, this needs checking: the record may be old or wrong, or the product intended for another market.
CosIng, Annex II of Regulation (EC) No 1223/2009 (prohibited substances), retrieved 23 October 2026, source updated 13 October 2026.
Origin and odour
No natural occurrence recorded in Wikidata (LOTUS database); this does not prove that the ingredient is synthetic.
Basis: one CosIng CAS, with no natural occurrence recorded in this database.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Other names: 2,4,6-trimethylbenzoyl diphenylphosphine oxide (English), Diphenyl(2,4,6-trimethylbenzoyl)phosphinoxid (German).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Present in 0.0% of recorded cosmetics (0 out of 22 328).
Open Beauty Facts, export of cosmetic products, retrieved 23 October 2026.
Data “Open Beauty Facts and its contributors”, licensed under ODbL 1.0 (opendatacommons.org/licenses/odbl/1-0); derived table distributed under the same licence.
The text of the annexes
Prohibited in cosmetics
CosIng links the name TRIMETHYLBENZOYL DIPHENYLPHOSPHINE OXIDE to this Annex II entry.
- Entry
- Annex II, No 1731
- Substance
- diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide; INCI: Trimethylbenzoyl Diphenylphosphine Oxide
- CAS
- 75980-60-8
- EC
- 278-355-8
Dates in the act (2)
- Entry into force on 2 June 2025
- Application from 1 September 2025
It shall apply from 1 September 2025.
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Regulation (EC) No 1223/2009, Annex II, entry 1731. CosIng, Annex II of Regulation (EC) No 1223/2009 (prohibited substances), retrieved 23 October 2026, source updated 13 October 2026.
Entry from Regulation (EU) 2025/877, adopted on 12 May 2025.
What has changed, and what will change
Dates of the texts that cover this ingredient. A text date may cover several substances: the details of each entry are below.
Annex II, entry 1731: introduced or replaced by Regulation (EU) 2025/877
Annex II, entry 1731: applies from this date
Identity
- CosIng identifier
- 87159
- CAS (according to CosIng)
- 75980-60-8
- EC (according to CosIng)
- 278-355-8
- Declared functions
- Nail sculpting
- Wikidata
- Q27274548
- PubChem
- 166480
- ECHA InfoCard
- 100.071.211
- InChIKey
- VFHVQBAGLAREND-UHFFFAOYSA-N
CosIng inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.
Wikidata, items with a CosIng identifier (P3073), retrieved 22 October 2026.
Wikidata, PubChem and ECHA links are published only when verified: same CosIng identifier, a single item, matching CAS number.
EU product alerts (Safety Gate)
1 alert on cosmetic products cite this name in their hazard description. An alert targets a specific product, not the ingredient itself. Under each alert, its reason (prohibited substance, limit exceeded, missing labelling, and so on), as published.
- 12 December 2025: Nail gel, NailsUp, Germany (“Serious risk”) alert
The product contains dyes CI 45170, Cl 45160 and Basic Yellow 40, p-hydroxyanisole, trimethylbenzoyl diphenylphosphine oxide (TPO) and 2-hydroxyethyl methacrylate (HEMA).which are banned in cosmetic products.All these can cause serious eye or skin irritation…
Safety Gate, EU rapid alert system for dangerous non-food products: cosmetic alerts from the weekly reports, retrieved 23 October 2026.
Source: European Commission, Safety GateEU rapid alert system for dangerous non-food products. weekly reports (CC0).
Elsewhere in the world
Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.
Comparison between countries
Most restrictive status in each country, and the maximum concentration cited. The details and the source of each rule follow.
| Country | Rule | Maximum concentration cited |
|---|---|---|
| European Union | Prohibited in cosmetics | not cited |
| United Kingdom | Prohibited in cosmetics | 5% |
| Switzerland | EU Regulation applies | not cited |
| United States (federal) | No federal rule recorded | not cited |
| Canada | No entry in the lists recorded | not cited |
| Japan | No entry in the lists recorded | not cited |
| South Korea | No entry in the lists recorded | not cited |
| China | Not on the prohibited lists recorded (lists of allowed substances are not recorded) | not cited |
| Australia | No entry in the lists recorded | not cited |
| ASEAN | Restricted (conditions or maximum concentration) differs from the EU | 5% |
| Taiwan | No entry in the lists recorded | not cited |
| Brazil | Prohibited | not cited |
United Kingdom (Great Britain)
- Prohibited in cosmetics (Annex II)
- Allowed with restrictions (Annex III)
Entry 311 of Annex III exists only in British law.
Annexes II to VI in force. United Kingdom, Annexes II to VI of Regulation (EC) No 1223/2009 as retained and amended, retrieved 21 October 2026.
Contains public sector information licensed under the Open Government Licence v3.0.
Northern Ireland applies EU law.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
Switzerland, FDHA Ordinance on Cosmetic Products (OCos, SR 817.023.31), consolidated version, retrieved 22 October 2026.
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
United States, 21 CFR part 700 and section 250.250 (FDA rules on cosmetic ingredients), eCFR, retrieved 21 October 2026.
The eCFR is not an official legal edition of the Code of Federal Regulations.
ASEAN (South-East Asia)
- Restricted (conditions or maximum concentration): Diphenyl(2,4,6- trimethylbenzoyl) phosphine oxide Trimethylbenzoyl diphenylphosphine oxide
Annex III (restricted substances), entry 336, page 251. Limit: 5.0%.
Conditions, source text
Ref column: (311) | Field of application and/or use: Artificial nail systems | Other limitations and requirements: Professional use | Conditions of use and warning which must be printed on the labels: For professional use only Avoid skin contact Read directions for use carefully
ASEAN Cosmetic Directive, Annexes II, III, IV, VI and VII (version 2026-1 of 22 June 2026, Annex VII 2025-2), retrieved 24 October 2026.
Source: ASEAN Cosmetic Documents, Annexes of the ASEAN Cosmetic Directive, as published by the Health Sciences Authority (HSA, Singapore); table extracted and formatted by the publisher of this site, with no endorsement by HSA or ASEAN.
Brazil
- Prohibited: Óxido de difenil(2,4,6-trimetilbenzol)fosfina
RDC 529/2021, Anexo (prohibited substances): alterações by RDC 1.030/2026, Art. 3º, entry 1418, page 5.
Conditions, source text, in Portuguese
Nº UE: 1731
Brazil, ANVISA resolutions RDC 529/2021, 528/2021, 600/2022 and 628/2022, retrieved 22 October 2026.
Source: ANVISA. Text of the adopted draft resolutions, as the Official Journal could not be accessed; the 2021 lists of prohibited substances and preservatives were compared with the copy of the published text distributed by the State of Paraná, the 2022 lists of UV filters and colorants were not.
Recorded cosmetics that contain it
2 recorded products list it, according to Open Beauty Facts contributors. Records are dated: the formula may have changed. See the list (in French).
Open Beauty Facts, export of cosmetic products, retrieved 23 October 2026.
Data “Open Beauty Facts and its contributors”, licensed under ODbL 1.0 (opendatacommons.org/licenses/odbl/1-0); derived table distributed under the same licence.
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 23 October 2026.