SAMe
SAMe, licence 80074653: active licence in Health Canada data. The French and European references below do not constitute authorisation for sale in France or an assessment of safety or efficacy.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
Natural health product licensed in Canada
- Licence holder
- Designs for Health
- NPN or DIN-HM
- 80074653
- Status
- Active licence
- Licence date
- 28 December 2016
- Revision date
- Not provided
- Form
- Capsule
- Route of administration
- Orale
- Application type
- Non traditionnelle
If this product were sold in France
- Dose déclarée au-delà d'une limite
Vitamine B6: up to 10 mg a day according to the dosing instructions published by Health Canada (2 unités posologiques par jour au plus, pour les adultes), above the maximum dose of 2 mg set in France for a food supplement (2006 Order, not revised since November 2006).
arrêté du 9 mai 2006, annexe III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
A daily quantity is calculated only for an explicit adult oral dosage, stated per day and in a solid unit matching the product form. Ambiguous units, liquids, powders and paediatric doses are not extrapolated. A quantity not calculated is not compared with dose limits. This analysis does not constitute authorisation for sale in France or an assessment of safety or efficacy.
Composition
| Medicinal ingredient and source | Per dosage unit, according to the source | Maximum per day, adult |
|---|---|---|
| Vitamine B6 Source : 5-phosphate de pyridoxal | 5.0 milligramme | 10,000 µg |
| Folate Source : Acide L-5 méthyltétrahydrofolique, sel de glucosamine | 100.0 microgrammes | Not calculated |
| Vitamine B12 Source : Méthylcobalamine | 50.0 microgrammes | Not calculated |
| S-(5'-désoxyadénosin-5'-yl)-l-méthionine Source : S-Adenosyl-L-methionine disulfate tosylate | 200.0 milligramme | Not calculated |
Non-medicinal ingredients
Chlorure de calcium, Stéarate de magnésium, Cellulose microcristalline, Oxyde de calcium
Recommended doses in Canada
| Population | Age | Quantity per serving | Frequency |
|---|---|---|---|
| Adultes | Not specified | 2.0 Capsule | 1.0 Tous les jours |
Uses authorised in Canada
Helps to form red blood cells. Helps to maintain the body's ability to metabolize nutrients. Helps in energy metabolism and in tissue formation. Helps in the normal function of the immune system. Helps in energy metabolism in the body. Helps relieve pain due to osteoarthritis. Helps to support a healthy mood balance. Helps support healthy liver function.
A use authorised in Canada is not an authorised health claim in the European Union. See the health claims register.
Warnings in Canada
- Contre-indications
Do not use if you have bipolar disorder or manic depression. If you are taking antidepressants, hepatotoxic drugs, or monoamine oxidase (MAO) inhibitors, consult a physician before using this product. Do not use if you are pregnant or breastfeeding.
- Précautions et mises en garde
May cause mild gastrointestinal upset. Do not take at night since product may cause anxiety, restlessness and/or insomnia. For pain due to osteoarthritis: If symptoms persist or worsen, consult a health care practitioner.
- Effets indésirables connus
Product may cause anxiety, restlessness and/or insomnia.
Source
Official Health Canada record, licence 80074653
The formula sold in Europe under the same name may differ. This information does not replace advice from a doctor or pharmacist.
The evidence date of this ingredient list is unknown.
Has the product changed? Photograph the packaging.