Centrum Advance 12516
Natural health product licensed in Canada
- Other names
- Centrum Advance
- Licence holder
- Haleon Canada ULC
- NPN or DIN-HM
- 80076171
- Status
- Inactive licence
- Licence date
- 17 March 2017
- Revision date
- 4 March 2024
- Form
- Comprimé
- Route of administration
- Orale
- Application type
- Non traditionnelle
If this product were sold in France
- Dose déclarée au-delà d'une limite
Manganèse: up to 4.5 mg a day according to the dosing instructions published by Health Canada (1 unités posologiques par jour au plus, pour les adultes), above the maximum dose of 3.5 mg set in France for a food supplement (2006 Order, not revised since November 2006).
arrêté du 9 mai 2006, annexe III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
- Dose déclarée au-delà d'une limite
Vitamine B6: up to 4.5 mg a day according to the dosing instructions published by Health Canada (1 unités posologiques par jour au plus, pour les adultes), above the maximum dose of 2 mg set in France for a food supplement (2006 Order, not revised since November 2006).
arrêté du 9 mai 2006, annexe III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
A daily quantity is calculated only for an explicit adult oral dosage, stated per day and in a solid unit matching the product form. Ambiguous units, liquids, powders and paediatric doses are not extrapolated. A quantity not calculated is not compared with dose limits. This analysis does not constitute authorisation for sale in France or an assessment of safety or efficacy.
Composition
| Medicinal ingredient and source | Per dosage unit, according to the source | Maximum per day, adult |
|---|---|---|
| Biotine Source : Biotine | 40.5 microgrammes | Not calculated |
| Folate Source : Acide folique | 360 microgrammes | Not calculated |
| Iode Source : Iodure de potassium | 135 microgrammes | Not calculated |
| Chrome Source : Chlorure de chrome (III) hexahydraté | 31.5 microgrammes | Not calculated |
| Cuivre Source : Sulfate de cuivre (II) | 0.9 milligramme | 900 µg |
| Molybdène Source : Molybdate de sodium (VI) dihydraté | 40.5 microgrammes | Not calculated |
| Sélénium Source : Sélénate de sodium | 49.5 microgrammes | Not calculated |
| Vitamine B12 Source : Cyanocobalamine | 18 microgrammes | Not calculated |
| Riboflavine Source : Riboflavine | 2.88 milligramme | 2,880 µg |
| Vitamine D Source : Cholécalciférol Potency : 600 UI | 15 microgrammes | Not calculated |
| Bêta-carotène Source : bêta-carotène Potency : 2,700 UI | 1,620 microgrammes | Not calculated |
| Vitamine C Source : Acide ascorbique | 81 milligramme | 81,000 µg |
| (3R,3'R,6'R)-bêta,epsilon-carotène-3,3'-diol Source : Tagetes erecta - Fleur | 450 microgrammes | Not calculated |
| Lycopène tout trans Source : Lycopène | 540 microgrammes | Not calculated |
| Calcium Source : Carbonate de calcium | 180 milligramme | 180,000 µg |
| Potassium Source : Chlorure de potassium | 72 milligramme | 72,000 µg |
| Fer Source : Fumarate de fer (II) | 9 milligramme | 9,000 µg |
| Magnésium Source : Oxyde de magnésium | 45 milligramme | 45,000 µg |
| Manganèse Source : Sulfate de manganèse (II) monohydraté | 4.5 milligramme | 4,500 µg |
| Zinc Source : Oxyde de zinc | 6.75 milligramme | 6,750 µg |
| Vitamine A Source : Acétate de vitamine A Potency : 900 UI | 270 mcg EAR | Not calculated |
| Thiamine Source : Mononitrate de thiamine | 2.2 milligramme | 2,200 µg |
| Niacinamide Source : Niacinamide | 13.5 milligramme | Not calculated |
| Vitamine B6 Source : Chlorhydrate de pyridoxine | 4.5 milligramme | 4,500 µg |
| Vitamine E Source : Acétate de dl-alpha tocophéryle Potency : 45 UI | 20.3 mg AT | Not calculated |
| Vitamine K1 Source : Vitamine K1 | 22.5 microgrammes | Not calculated |
Non-medicinal ingredients
Acide l-tartrique, Dioxyde de titane, NA, Cellulose microcristalline, Trehalose, Acacia, Gélatine, Sucrose, Croscarmellose de sodium, Stéarate de calcium, Maltodextrine, Amidon de maïs, Huile de palme hydrogenée, dl-alpha tocophérol, Citrate de triéthyle, Phosphate de calcium, dibasique, anhydre, Dioxyde de silicium, Hydroxypropylméthylcellulose, Acide citrique, Huile minérale, Stéarate de magnésium, Amidon alimentaire, modifié, Crospovidone, Phosphate de calcium, dibasique, dihydraté, Sirop de glucose, Poly(sorbate) 80, Acide stéarique, Citrate de trisodium, Laque d'aluminium bleu FD&C No 2, Ascorbate de sodium
Recommended doses in Canada
| Population | Age | Quantity per serving | Frequency |
|---|---|---|---|
| Adultes | Not specified | 1 Comprimé | 1 Tous les jours |
Uses authorised in Canada
Text supplied in English because no French text is available.
Helps in the development and maintenance of bones, cartilage, teeth and/or gums. helps in connective tissue formation. Helps in wound healing. Source of/An antioxidant for the maintenance of good health. Sourceof/Anantioxidant thathelpsfight/protect (cell)against/reduce(theoxidativeeffect of/theoxidativedamage causedby/cell damage caused by) free radicals. Helpsin collagen formation to maintain healthy bones,cartilage, teeth and/or gums. Helps to maintain immune function. Helps to maintain the body's ability to metabolize nutrients. Source of/ An antioxidant for the maintenance of good heaIth/eye heaIth. Adequate calcium (and vitamin D) (throughout life) as part of a healthy diet, (along with physical activity) may reduce the risk of developing osteoporosis (in peri- and postmenopausal women) (in later life). Adequatecalcium (and vitamin D)(throughout life) as part of a healthy diet,(alongwithphysical activity) may help prevent boneloss/osetoporosis (in peri- and postmenopausal women) (in later life). Source of/An electrolyte for the maintenance of good health. Helps to maintain normal muscle function. Helps to form red blood cells and helps in their proper function. Helps in tissue formation. Helps to maintain proper musclefunction, including the heart muscle. Helpsin energy metabolism, tissueformationand bonedevelopment. Helps to maintain normal electrolyte balance. Helps to maintain healthy bones, hair,nail and/or skin. Helps to maintain eyesight/skin/membranes/(and) immune function (health). Helps in the development and maintenance of night vision. Helps to build strong bones and teeth. Helps to maintain normal metabolism of iron. Helps to maintain healthy skin and/or mucous membranes. Helps in the absorption and use of calcium and phosphorous. Helps in energy production. Helps normal growth anddevelopment. Helps to maintain normalred bloodcells. Helps in the normal function of the immune system. Helps in energy metabolism in the body. Source of/An antioxidant that protects the fat in body tissues from oxidation. Helps to maintain healthy hair, nail, mucous membranes and/ or skin. Helpsin the function of the thyroid gland. Provides support for healthy glucose metabolism. Helps to maintain normal blood glucose levels. Helps to produce and repair connective tissue. Helps to maintain normal iron transport in the body . Helps to maintain normal function of the thyroid gland. Calcium intake, when combined with sufficient Vitamin D, a healthy diet, and regular exercise, may reduce the risk of developing osteoporosis. Source of/ An antioxidant that helps protect against oxidative stress. Multivitamin/ multimineral supplement.
A use authorised in Canada is not an authorised health claim in the European Union. See the health claims register.
Warnings in Canada
- Précautions et mises en garde
Keep out of reach of children. Do not exceed the recommended daily dose. If taking other supplements, read label, as other supplements may contain the same ingredients. There is enough iron in this package to seriously harm a child. Consult a healthcare practitioner prior to use if you are taking blood thinners. In case of accidental overdose, contact a physician or poison control centre immediately.
Source
Official Health Canada record, licence 80076171
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
The formula sold in Europe under the same name may differ. This information does not replace advice from a doctor or pharmacist.
List in the official revision dated (register: Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks).
List recorded in 2024. Photograph the packaging to check whether it has changed. Photograph the packaging