Migraine Defense
Natural health product licensed in Canada
- Licence holder
- Naticura Inc.
- NPN or DIN-HM
- 80105265
- Status
- Active licence
- Licence date
- 15 October 2020
- Revision date
- Not provided
- Form
- Capsule
- Route of administration
- Orale
- Application type
- Générale (non traditionelle)
If this product were sold in France
- Dose déclarée au-delà d'une limite
Vitamine B6: up to 12.5 mg a day according to the dosing instructions published by Health Canada (1 unités posologiques par jour au plus, pour les adultes), above the maximum dose of 2 mg set in France for a food supplement (2006 Order, not revised since November 2006).
arrêté du 9 mai 2006, annexe III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
- À vérifier
Vitamine B6: up to 12.5 mg a day according to the dosing instructions published by Health Canada, above the limite de sécurité from EFSAEuropean Food Safety Authority. for adults (12 mg a day). Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
limite supérieure de sécurité (UL). EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
A daily quantity is calculated only for an explicit adult oral dosage, stated per day and in a solid unit matching the product form. Ambiguous units, liquids, powders and paediatric doses are not extrapolated. A quantity not calculated is not compared with dose limits. This analysis does not constitute authorisation for sale in France or an assessment of safety or efficacy.
Composition
| Medicinal ingredient and source | Per dosage unit, according to the source | Maximum per day, adult |
|---|---|---|
| Vitamine B12 Source : Cyanocobalamine | 0.2 mcg | 0.2 µg |
| 2,5-Cyclohexadiène-1,4-dione, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-décaméthyl-2,6,10,14,18,22,26,30,34,38-tétracontadécaényl]-5,6-diméthoxy-3-méthyl Source : Coenzyme Q10 | 75 mg | Not calculated |
| Tanacetum parthenium Source : Sommité Extract : Matériel brut sec Extraction ratio : 4:1 Dry plant equivalent : 400 mg Potency : 0.4 % Parthenolide | 100 mg | Not calculated |
| Riboflavine Source : Riboflavine | 25 mg | 25,000 µg |
| Withania somnifera Source : Racine Extract : Matériel brut sec Extraction ratio : 40:1 Dry plant equivalent : 1,000 mg Potency : 2.5 % Withanolides | 25 mg | Not calculated |
| Petasites hybridus Source : Racine Extract : Matériel brut sec Extraction ratio : 4:1 Dry plant equivalent : 300 mg | 75 mg | Not calculated |
| Vitamine B6 Source : Chlorhydrate de pyridoxine | 12.5 mg | 12,500 µg |
Non-medicinal ingredients
Hypromellose
Recommended doses in Canada
| Population | Age | Quantity per serving | Frequency |
|---|---|---|---|
| Adultes | minimum: 19 years | 1 Capsule | 1 Tous les jours |
Uses authorised in Canada
(Used in Herbal Medicine to) help(s) prevent migraine headaches. (Used in Herbal Medicine to) help(s) reduce the severity and/or frequency of migraine headaches and associated symptoms such as nausea and vomiting, when taken as a prophylactic.
A use authorised in Canada is not an authorised health claim in the European Union. See the health claims register.
Warnings in Canada
- Effets indésirables connus
Do not use if you are allergic to plants of the Asteraceae/Compositae/Daisy family. Hypersensitivity, such as allergy, has been known to occur; in which case, discontinue use immediately. Some people may experience sore mouth, mouth ulcers and/or gastrointestinal discomfort.
- Contre-indications
Do not use if you are pregnant.
Source
Official Health Canada record, licence 80105265
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
The formula sold in Europe under the same name may differ. This information does not replace advice from a doctor or pharmacist.
The evidence date of this ingredient list is unknown.
Has the product changed? Photograph the packaging.