Clear Change Daily Essentials
Natural health product licensed in Canada
- Other names
- AdvaClear, GlutaClear, KD Plus
- Licence holder
- Metagenics Inc.
- NPN or DIN-HM
- 80144318
- Status
- Active licence
- Licence date
- 22 September 2025
- Revision date
- 28 October 2025
- Form
- Kit
- Route of administration
- Orale
- Application type
- Générale (non traditionelle)
If this product were sold in France
- Conditions légales
Contains tea (Camellia sinensis). Green tea extracts must provide less than 800 mg of epigallocatechin-3-gallate per daily portion, with mandatory warnings.
annexe III, partie B (règlement (UE) 2022/2340). Regulation (EC) No 1925/2006, latest consolidated version, retrieved 21 October 2026.
- Conditions légales
Brassica oleracea L.: L'étiquetage doit comporter un avertissement recommandant aux personnes ayant une hypothyroïdie ou un traitement de la thyroïde de consulter leur médecin.
arrêté du 24 juin 2014, annexe I. French orders of 9 May 2006 (nutrients), 24 June 2014 (plants) and 26 September 2016 (other substances), consolidated LEGI collection, retrieved 23 October 2026.
- Conditions légales
Camellia sinensis (L.) Kuntze: Seules sont admises la poudre issue du broyage des feuilles et les préparations obtenues à partir des solvants suivants : l'eau, l'alcool à 25 % (v/v), ainsi que les solvants autorisés pour la décaféination ou la suppression des matières irritantes et amères. Les recommandations d'emploi ne doivent pas conduire à une ingestion quotidienne d'EGCG supérieure à 300 mg. L'étiquetage doit comporter des avertissements déconseillant leur prise en dehors des repas, ainsi que leur consommation par les enfants, les adolescents, les femmes enceintes ou allaitantes.
arrêté du 24 juin 2014, annexe I. French orders of 9 May 2006 (nutrients), 24 June 2014 (plants) and 26 September 2016 (other substances), consolidated LEGI collection, retrieved 23 October 2026.
A daily quantity is calculated only for an explicit adult oral dosage, stated per day and in a solid unit matching the product form. Ambiguous units, liquids, powders and paediatric doses are not extrapolated. A quantity not calculated is not compared with dose limits. This analysis does not constitute authorisation for sale in France or an assessment of safety or efficacy.
Composition
| Medicinal ingredient and source | Per dosage unit, according to the source | Maximum per day, adult |
|---|---|---|
| Cynara cardunculus Source : Cynara cardunculus - Feuille Extract : Matériel brut sec Extraction ratio : 10:1 Dry plant equivalent : 830 mg | 83 mg | Not calculated |
| Vitamine E Source : Succinate d'acide de d-alpha tocophéryle | 22 mg AT | Not calculated |
| N-Acétyl-L-cystéine Source : N-Acétyl-L-cystéine | 375 mg | Not calculated |
| Brassica oleracea var. italica Extract : Matériel brut sec Extraction ratio : 20:1 Dry plant equivalent : 385 mg Potency : 2.5 mg Glucoraphanin | 19.25 mg | Not calculated |
| Sélénium Source : Sélénométhionine | 37.5 Microgrammes | Not calculated |
| Vitamine B12 Source : Méthylcobalamine | 16.6 Microgrammes | Not calculated |
| Vitamine B6 Source : Chlorhydrate de pyridoxine | 8 mg | Not calculated |
| Vitamine C | 250 mg | Not calculated |
| Niacine Source : Acide nicotinique | 5 mg | Not calculated |
| Acide pantothénique Source : D-Pantothénate de calcium | 16.5 mg | Not calculated |
| Paecilomyces hepiali Extract : Matériel brut sec Extraction ratio : 8:1 Dry plant equivalent : 1,600 mg Potency : 0.25 % Adenosine | 200 mg | Not calculated |
| Salvia miltiorrhiza Extract : Matériel brut sec Extraction ratio : 8:1 Dry plant equivalent : 1,600 mg | 200 mg | Not calculated |
| Vitamine B6 Source : Chlorhydrate de pyridoxine | 10 mg | Not calculated |
| N-Acétyl-L-cystéine Source : N-Acétyl-L-cystéine | 33 mg | Not calculated |
| Folate Source : L-5 Méthyltétrahydrofolate, sel de calcium | 134 Microgrammes | Not calculated |
| Niacinamide Source : Niacinamide | 375 mg | Not calculated |
| Sélénium Source : Sélénométhionine | 25 Microgrammes | Not calculated |
| Camellia sinensis Source : Camellia sinensis - feuille Potency : 4 % Caffeine | Not specified | Not calculated |
Non-medicinal ingredients
Hydroxypropylcellulose, Cellulose, Dioxyde de silicium, NA, Acide stéarique, Hypromellose, Stéarate de magnésium, Sulfate de sodium, dérivé sodium-cuivre de la chlorophylline
Recommended doses in Canada
| Population | Age | Quantity per serving | Frequency |
|---|---|---|---|
| Adultes | minimum: 18 years | 1 Comprimé | 1 Tous les jours |
| Adultes | minimum: 18 years | 1 Capsule | 1 Tous les jours |
| Adultes | minimum: 18 years | 2 Capsule | 1 Tous les jours |
Uses authorised in Canada
Text supplied in English because no French text is available.
Used in Herbal Medicine to help relieve digestive upset, such as indigestion and help increase bile flow(choleretic). Source of antioxidants/Provides antioxidants that help fight/protect (cell) against/reduce (the oxidative effect of/the oxidative damage caused by/cell damage caused by) free radicals. Source of vitamin(s)/mineral(s)/vitamin(s) and mineral(s) to support biological functions which play a key role in the maintenance of good health. Source of vitamin(s)/mineral(s)/vitamin(s) and mineral(s), a factor/factors in the maintenance of good health. Helps in energy metabolism and tissue formation.
A use authorised in Canada is not an authorised health claim in the European Union. See the health claims register.
Warnings in Canada
No French warning text available in the imported data.
Warnings are available in English on the official record.
Source
Official Health Canada record, licence 80144318
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
The formula sold in Europe under the same name may differ. This information does not replace advice from a doctor or pharmacist.
List in the official revision dated (register: Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks).
Has the product changed? Photograph the packaging.