5-hydroxytryptophane in food supplements
24 supplements declared in France contain 5-hydroxytryptophane as a substance or active ingredient.
Declarations also use the name: L-5-Hydroxytryptophane. Separate page, as the form (L or D) is not always stated.
Other names in the Compl'Alim list: 5-HTP, Oxitriptan, 5-hydroxytryptophan.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Appearance
L-5-hydroxytryptophan appears as colorless to pale pink crystals. (NTP, 1992)
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04520178 : Effects of 5HTP on the Injured Human Spinal Cord
ACTIVE_NOT_RECRUITING · PHASE2, PHASE3 · Spinal Cord Injuries · 2026-09-16 · 5-Hydroxytryptophan
- NCT05895747 : 5-HTP and Creatine for Depression R33 Phase
RECRUITING · PHASE2 · Major Depressive Disorder · 2026-08-27 · Low Dose 5-hydroxytryptophan (synonym declared in the registry); High Dose 5-hydroxytryptophan (synonym declared in the registry)
- NCT04160910 : 5HTP Regulation Of Asthma In Children
RECRUITING · PHASE2 · Mild or Moderate Asthma With Allergic Sensitization · 2026-10-01 · 5-Hydroxytryptophan
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (5-hydroxytryptophane) : humeur (6 produits), sommeil (5 produits), ménopause (3 produits), minceur / brûleur (2 produits), système nerveux (2 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Nouvel aliment ou pas
Classé par le catalogue comme nouvel aliment non encore autorisé : sous la forme visée par l'entrée, il ne devrait pas être vendu dans l'Union tant qu'il n'est pas autorisé. Le catalogue est informatif ; une déclaration en France (« commercialisation possible ») n'est pas une autorisation.
Le catalogue de la Commission est indicatif : il ne remplace pas une décision.
Novel Food Catalogue (status of products under Regulation (EU) 2015/2283), retrieved 21 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Novel food catalogue (European Union), entry “5-hydroxytryptophan”: Classé par le catalogue comme nouvel aliment non encore autorisé : sous la forme visée par l'entrée, il ne devrait pas être vendu dans l'Union tant qu'il n'est pas autorisé. Le catalogue est informatif ; une déclaration en France (« commercialisation possible ») n'est pas une autorisation.
POL-NF-00063. Novel Food Catalogue (status of products under Regulation (EU) 2015/2283), retrieved 21 October 2026.
Health claims register (European Union): 0 authorised and 2 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed and flagged as a novel food.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 4 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 765 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 1 product.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Products
- 5-HTP Zumub, gélule, declared in 2022
- 5-HTP capsule, flavour sans saveur, declared in 2020
- 5-HTP comprimé, declared in 2020
- 5-HTP capsule, declared in 2018
- 5-HTP Complex Zenement, gélule, declared in 2021
- FORMULE MENOACTIVE HDNC, gélule, declared in 2019
- GRIFFONIA 5-HTP L'Herbôthicaire, gélule, declared in 2019
- GRIFFONIA 5-HTP LJDV Les Jardins du Vercors, gélule, declared in 2023
- GRIFFONIA 5-HTP PARAKEYA Parakeya, gélule, declared in 2023
- MENOACTIFS Laboratoires SYNActifs, gélule, declared in 2020
- S-plex gélule, declared in 2020
- Sinaptic complex gélule, declared in 2017
- Super Bombasse YAM, comprimé, declared in 2024
- WeightWorld 5-HTP 98mg 60 Gummies autre :, declared in 2023
- WeightWorld 5HTP 490mg 365 Tablets capsule, declared in 2022
- ZEN gélule, declared in 2020
- Zen Stress Control Vitality Nutritionals, capsule, declared in 2020
- myVeggie Sommeil myVeggie, gélule, declared in 2022
- 5-HTP labkaps, gélule, withdrawn from the market
- DIETOLYA APRES MIDI ESTHELYA, comprimé, withdrawn from the market
- EMO'STRESS gélule, withdrawn from the market
- Feminabiane Méno’confort Pileje, comprimé, withdrawn from the market
- SOMACTIFS Laboratoires SYNActifs, gélule, withdrawn from the market
- noxidrim gélule, withdrawn from the market
Other related records
- 5-HTP Natural health product licensed in Canada
- 5-HTP Products notified in Poland, composition to complete
- Stress Shield Supplement from the US market
- 5-HTP 100 mg Supplement from the US market
- 5-HTP L-5-Hydroxy-Tryptophan 200 mg Supplement from the US market
- Relaxation 5-HTP 200 mg Supplement from the US market
- Limitless Mind Supplement from the US market
- Brain Mood Supplement from the US market
- 5-HTP Supplement from the US market
- 5-HTP 100 mg : étiquette retirée du marché américain Supplement from the US market
- 5-HTP 100 mg Supplement from the US market
- 5-HTP (Griffonia Simplicifolia Extract) 100 mg Supplement from the US market
- 5-HTP 50 mg Supplement from the US market
- Seratran Supplement from the US market
- Hypnosom Tablets Supplement from the US market
- Cut XT Supplement from the US market
- Neur-AutonomeXX Supplement from the US market
- Stress Matters Supplement from the US market
- 5-HTP 50 mg Supplement from the US market
- 5-HTP 100 mg Supplement from the US market
- 5-HTP 200 mg Time Release Supplement from the US market
- 5-HTP 100 mg Time Release Supplement from the US market
- Melatonin + 5-HTP Advanced Time Release Supplement from the US market
- Relax+ Ultimate Calm Supplement from the US market
- 5-HTP 200 mg Time Release Supplement from the US market
- Sleep Support Supplement from the US market
- Serotone 5-HTP 50 mg Supplement from the US market
- Serotone 5-HTP 50 mg Supplement from the US market
- Serotone 5-HTP 100 mg Supplement from the US market
- Serotone 5-HTP 100 mg Supplement from the US market
- 5-HTP 100 mg Supplement from the US market
- 5-HTP Powder Supplement from the US market
- Metadrine Supplement from the US market
- SleepEasy Supplement from the US market
- CereVive Jr. Berry Supplement from the US market
- 5-HTP Supplement from the US market
- Focus Fast : étiquette retirée du marché américain Supplement from the US market
- 5-HTP 100 mg Supplement from the US market
- Sleep Formula Supplement from the US market
- Mood Supplement from the US market
- Completely Calm Supplement from the US market
- 5-HTP Plus Supplement from the US market
- Sleep Complex with Melatonin Supplement from the US market
- Cytolean Night Time PM Formula Supplement from the US market
- Sleep Formula Supplement from the US market
- Phenocal Supplement from the US market
- Serene Supplement from the US market
- Daxitrol Essential Supplement from the US market
- SeroTrex Orange Flavored Chewables Supplement from the US market
- Alpha GABA PM Supplement from the US market
- Lights Out Sleep Supplement from the US market
- Cyclin With Growth Factors Supplement from the US market
- Sleep Aid : étiquette retirée du marché américain Supplement from the US market
- Sleep Solve 24/7 Supplement from the US market
- 5-HTP Supplement from the US market
- 5-HTP 100 mg Supplement from the US market
- Celexil : étiquette retirée du marché américain Supplement from the US market
- Oxotrim Supplement from the US market
- 5-HTP 50 mg : étiquette retirée du marché américain Supplement from the US market
- 5-HTP 5-Hydroxytryptophan 50 mg Supplement from the US market