Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- MULTI VITAMINE SANUCIB, gélule, declared in 2026
- MULTI VITAMINE gélule, declared in 2026
- MULTI VITAMINES ABINTUS, gélule, declared in 2021
- MULTIVIT'AL ALTHEA NUTRITION, gélule, declared in 2026
- MULTIVIT'FOCUS poudre, declared in 2026
- MULTIVITAMIN comprimé, declared in 2024
- MULTIVITAMINE comprimé, declared in 2025
- MULTIVITAMINE SVELTA, gélule, declared in 2024
- MULTIVITAMINE gélule, declared in 2026
- MULTIVITAMINES gélule, declared in 2026
- MULTIVITAMINES gélule, declared in 2021
- MULTIVITAMINES YAM NUTRITION, gélule, declared in 2025
- MULTIVITAMINES Nutripure, gélule, declared in 2025
- MULTIVITAMINES DIVINACTIV, gélule, declared in 2025
- MULTIVITAMINES & MINERAUX ROYALYS, gélule, declared in 2026
- MULTIVITAMINES COMPLEXE SPOM, gélule, declared in 2026
- MULTIVITAMINS COMPLEX Nutralie, capsule, declared in 2024
- MY Essentiels activateurs de métabolisme poudre, declared in 2026
- MY OPK LABORANTIN, gélule, declared in 2026
- MY OPK LABORANTIN, gélule, declared in 2026
- Macrominéraux SPORT EcogeneticsN, sachet, flavour arôme naturel d'orange sanguine, declared in 2022
- Magic Glutathion gélule, declared in 2026
- Majflu550 sachet, declared in 2025
- Masse Capillaire D-LAB NUTRICOSMETICS, autre : activateur d'équilibre: gélules, absolu de kératine: comprimés & détox microcirculation: gélules, declared in 2023
- MaxGXL Max International, gélule, declared in 2017
- Memo Complex Vitaminor, gélule, declared in 2018
- Memoire Suplemint, autre : gélules et comprimé, declared in 2023
- Menopause (Multi Vit) 4/5 Suplemint, gélule, declared in 2025
- MercuClean gélule, declared in 2019
- MetaClear comprimé, declared in 2018
- MetaDetox 360 poudre, flavour goût vanille, declared in 2024
- MetaDetox® comprimé, declared in 2025
- MetaDetox® comprimé, declared in 2025
- MetaDetox® comprimé, declared in 2025
- MetaSkin comprimé, declared in 2025
- Metal'Oust gélule, declared in 2017
- Milk Thistle Formula VITORTHO, gélule, declared in 2026
- Minceur autre : gélules + sachet, declared in 2019
- Mineavit'Vitalité 50+ Diétaroma, comprimé, declared in 2025
- Mito process matin gélule, declared in 2025
- MitoDyn gélule, declared in 2018
- MitoDyn gélule, declared in 2018
- Mitochondrie gélule, declared in 2017
- Mitochondrie Gold gélule, declared in 2024
- Mitochondries gélule, declared in 2026
- Mitochondries Waybio gélule, declared in 2026
- Mitochondryn gélule, declared in 2018
- Mitofast complément alimentaire orodispersible Mitochon, poudre, declared in 2026
- Mitolistique gélule, declared in 2026
- Mitolistique gélule, declared in 2026
- Mix acides aminés poudre, declared in 2026
- Mucilyse Biophénix, gélule, declared in 2024
- MucoPha gélule, declared in 2021
- Multi gélule, declared in 2018
- Multi Essentiel 50+ sachet, flavour goût orange-citron, declared in 2024
- Multi Essentiel Active Plus gélule, declared in 2025
- Multi Essentiel Active Plus gélule, declared in 2025
- Multi Essentiel Ado sachet, flavour goût orange-citron, declared in 2025
- Multi Essentiel Ado sachet, flavour goût orange-citron, declared in 2024
- Multi vitamines gélule, declared in 2022