Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- Glutathion gélule, declared in 2021
- Glutathion NUTRIMEA, gélule, declared in 2017
- Glutathion Physiosources, gélule, declared in 2026
- Glutathion + gélule, declared in 2017
- Glutathion 100 Acides aminés+ gélule, declared in 2025
- Glutathion 180 gélule, declared in 2026
- Glutathion 90 Phyto 5, gélule, declared in 2026
- Glutathion Complexe 1600 Orfito bioactive, gélule, declared in 2019
- Glutathion R Complex gélule, declared in 2025
- Glutathion Synergie Djform, gélule, declared in 2025
- Glutathion intracel Pronature, gélule, declared in 2017
- Glutathion max gélule, declared in 2025
- Glutathion Équilibre Premium gélule, declared in 2026
- Glutathion-NAC Herbolistique, gélule, declared in 2022
- Glutathione with Silymarin, NAC & LOLA Osavi, gélule, declared in 2026
- GlyNAC SuperSmart, gélule, declared in 2026
- GlyNAC Clarity Purovitalis, gélule, declared in 2025
- Gynovital Sopk Oligosanté, sachet, flavour pêche, declared in 2024
- H-DETOX NUTRYTEC, capsule, declared in 2017
- H-PABOL COMPLEX HCF LABORATORIES, capsule, declared in 2018
- HEALTHY VITA SILYGAMA gélule, declared in 2025
- HEPA CLEAR SO.LAB, gélule, declared in 2026
- HEPA CONFORT Nutrigée, comprimé, declared in 2026
- HEPA PRO gélule, declared in 2025
- HEPACYTE NHCO NUTRITION, comprimé, declared in 2021
- HEPAPRO LIFE PRO, capsule, declared in 2022
- HEPAREGUL gélule, declared in 2020
- HEPASIL DTX USANA, comprimé, declared in 2017
- HEPAT + NR&D, gélule, declared in 2021
- HEPATIC JOUR & NUIT PLEVITON, gélule, declared in 2026
- HEPATILIUM NAODIA, comprimé, flavour /, declared in 2022
- HEPATO+ DIET HORIZON, comprimé, declared in 2026
- HEPATO+ DIET HORIZON, comprimé, declared in 2023
- HEPATOBIOTIK capsule, declared in 2019
- HEPATOtab Pharmaciens Preparateurs, autre : comprimés pelliculés, declared in 2020
- HEPATRAIT gélule, declared in 2022
- HERBA DETOX gélule, declared in 2021
- HERBECOM MUCUS Bioserum, gélule, declared in 2024
- HERBETOM SÉCRÉTION Bioserum, gélule, declared in 2025
- HORBÄACH - NAC N-ACETYL-CYSTEINE gélule, declared in 2025
- HORMONE BALANCE SAHIYA, poudre, declared in 2026
- HORMONIUM PhysioNat, gélule, flavour aucun, declared in 2026
- HYCONO Fruits Rouges Crown eSports Nutrition, poudre, flavour fruits rouges, declared in 2026
- HYPER BEAST NANOSUPPS, poudre, flavour mélange de baies, declared in 2023
- HYPER BEAST NANOSUPPS, poudre, flavour pomme verte, declared in 2023
- HYPER PUMP Nanosupps, poudre, flavour pêche mangue, declared in 2023
- HYPER PUMP Nanosupps, poudre, flavour fraise-kiwi, declared in 2023
- HYPER PUMP Nanosupps, poudre, flavour pomme verte, declared in 2023
- Hair Full Cycle gélule, declared in 2020
- Hair, Skin & Nails 60 tabs PROZIS, comprimé, declared in 2019
- Hang Over comprimé, declared in 2020
- Hang Over comprimé, declared in 2022
- HangRelief HangRelief, poudre, flavour orange, declared in 2026
- HangRelief HangRelief, poudre, flavour lemon lime, declared in 2026
- HangRelief HangRelief, poudre, flavour pineapple, declared in 2026
- HangRelief HangRelief, poudre, flavour rose lychee, declared in 2026
- Health Pak USANA, comprimé, declared in 2017
- Hepato Health MEDENDA, gélule, declared in 2021
- Hepaxis DarmAxis, gélule, declared in 2018
- Herbal Mix Vitamintrend, gélule, declared in 2022