CompoAtlas

Glucose in food supplements

116 supplements declared in France contain Glucose as a substance or active ingredient.

Other names in the Compl'Alim list: glucose.

Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.

What we know about this ingredient

Uses

  • ...Instead of lactose, as a supplement to milk for infant feeding.

  • Benzylisoquinoline alkaloids (BIAs) are a diverse family of plant-specialized metabolites that include the pharmaceuticals codeine and morphine and their derivatives. Microbial synthesis of BIAs holds promise as an alternative to traditional crop-based manufacturing. Here we demonstrate the production of the key BIA intermediate (S)-reticuline from glucose in Saccharomyces cerevisiae. To aid in this effort, we developed an enzyme-coupled biosensor for the upstream intermediate L-3,4-dihydroxyphenylalanine (L-DOPA). Using this sensor, we identified an active tyrosine hydroxylase and improved its L-DOPA yields by 2.8-fold via PCR mutagenesis. Coexpression of DOPA decarboxylase enabled what is to our knowledge the first demonstration of dopamine production from glucose in yeast, with a 7.4-fold improvement in titer obtained for our best mutant enzyme. We extended this pathway to fully reconstitute the seven-enzyme pathway from L-tyrosine to (S)-reticuline. Future work to improve titers and connect these steps with downstream pathway branches, already demonstrated in S. cerevisiae, will enable low-cost production of many high-value BIAs.

  • Confectionary, infant foods, medicine, brewing and wine making, intermediate, caramel coloring, baking and canning, source of methane by anaerobic fermentation, source of certain amino acids (e.g. lysine) by fermentation.

  • Nutrient (carbohydrate) replenisher in pharmaceuticals; food component; fluid replenisher

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Troy, D.B. (Ed); Remmington The Science and Practice of Pharmacy. 21 st Edition. Lippincott Williams & Williams, Philadelphia, PA 2005, p. 1085; PMID:25984720 DeLoache WC et al; Nat Chem Biol 11 (7): 465-71 (2015); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 609; SRI.

Licence.

Use classification

  • EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

  • Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

  • Cosmetics -> Humectant

PubChem : EPA Safer Choice · 2026-10-29 · https://www.epa.gov/saferchoice/safer-ingredients.

Licence.

PubChem : NORMAN Suspect List Exchange · 2026-10-29 · S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118.

Licence.

A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.

Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).

Natural occurrence recorded in Wikidata (LOTUS database): 220 taxa; examples: Gentianopsis barbata, Gentianopsis barbellata, Medicago sativa, Allium cepa, Allium ampeloprasum.

Manufacturing

  • Dextrose is manufactured almost exclusively from corn (maize) starch in the United States. In other countries, starch from sorghum (milo), wheat, rice, potato, tapioca (yucca, cassava), arrowroot, and sago are used to varying degrees along with corn starch. Prior to the 1960s, commercial dextrose was produced using acid and acid-enzyme hydrolysis processes that yielded only about 86 and 92-94% dextrose, respectively. The development of thermostable bacterial a-amylase enzymes led to total enzyme processes that eliminated acid degradation products and increased dextrose yield to about 95-97%. In an enzymatic process, starch is hydrolyzed (thinned or liquefied) with a bacterial a-amylase. The resulting substrate is then hydrolyzed to dextrose (saccharified) using glucoamylase, a fungal enzyme that preferentially cleaves dextrose from the partially degraded starch. The initial extent of liquefaction is generally in the range of 10-20 dextrose equivalent (DE). DE is a measure of the reducing-sugar content calculated as dextrose and expressed as a percentage of the total dry substance. Several industrial enzyme liquefaction processes are used commercially. These processes are referred to as (1) enzyme-heat-enzyme, (2) low temperature, (3) dual enzyme/dual heating, (4) dual enzyme/single heating, and (5) thermal liquefaction.

  • Hydrolysis of cornstarch with acids or enzymes, hydrolysis of cellulosic wastes.

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Hebeda RE; Syrups. Kirk-Othmer Encyclopedia of Chemical Technology (1999-2016). John Wiley & Sons, Inc. Online Posting Date: May 18, 2007; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 609.

Licence.

Appearance

  • Colorless crystals or white granular powder

  • Watery odorless colorless liquid. Denser than water and soluble in water. Hence sinks in and mixes with water. (USCG, 1999)

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 609.

Licence.

PubChem : CAMEO Chemicals · 2026-10-29 · U.S. Coast Guard. 1999. Chemical Hazard Response Information System (CHRIS) - Hazardous Chemical Data. Commandant Instruction 16465.12C. Washington, D.C.: U.S. Government Printing Office..

Licence.

Odour described

  • Odorless

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 609.

Licence.

Stability

  • Stable under recommended storage conditions.

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Sigma-Aldrich; Safety Data Sheet for D-(+)-Glucose. Product Number: G8270, Version 4.4 (Revision Date 01/14/2015). Available from, as of January 29, 2016: https://www.sigmaaldrich.com/safety-center.html.

Licence.

Taste described

  • Sweet

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 609.

Licence.

Associated research

ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.

2026-11-01

Other names: glucosa (Spanish), glucosio (Italian), glicose (Portuguese).

Same substance in cosmetics: GLUCOSE.

In plain words

À quoi il sert, selon les fabricants

Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Glucose) : sport (27 produits), immunité (18 produits), système nerveux (7 produits), circulation sanguine et lymphatique (6 produits), humeur (6 produits).

Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.

What the registers say, country by country

Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.

Health claims register (European Union): 0 authorised and 5 refused claim(s) for this substance.

EU Register of nutrition and health claims, retrieved 21 October 2026.

Compl'Alim ingredient list (France): listed.

Compl'Alim, reference list of ingredients, retrieved 21 October 2026.

United States, supplement labels (DSLD; supplements need no prior approval): 17 products.

Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.

Taiwan, registered products: 65 products.

TFDA, Taiwan tablets, capsules and medical nutrition registers, retrieved 27 October 2026.

Taiwan Food and Drug Administration (TFDA), Open Government Data License, version 1.0

Open Government Data License, version 1.0

United States, supplements listed by the USDA: 28 products.

USDA FoodData Central Branded, supplement cohort, retrieved 29 October 2026.

Source : U.S. Department of Agriculture, Agricultural Research Service, FoodData Central, Branded Foods. Données publiées sous CC0 1.0 Universal, https://creativecommons.org/publicdomain/zero/1.0/.

CC0 1.0 Universal, domaine public

Declared daily quantities

Declared daily quantities: Glucose
UnitProductsMedianMinimumMaximum
mg952,268190,000

Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.

Products

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