CompoAtlas

Histidine in food supplements

536 supplements declared in France contain Histidine as a substance or active ingredient.

Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.

What we know about this ingredient

Uses

  • Infusion solutions/diagnostic aids; raw material (peptide drugs)

  • Medicine, feed additive, biochemical research, dietary supplement

  • Calculated removal (%): 75.1

  • Consumption (g per capita; approx.) in Germany (2009): 0.122

  • Use (kg; approx.) in Germany (2009): >10000

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ashford, R.D. Ashford's Dictionary of Industrial Chemicals. London, England: Wavelength Publications Ltd., 1994., p. 472; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 578.

Licence.

PubChem : NORMAN Suspect List Exchange · 2026-10-29 · DOI:10.1021/acs.est.5b03332.

Licence.

Use classification

  • Cosmetics -> Skin conditioning; Humectant; Antistatic

PubChem : NORMAN Suspect List Exchange · 2026-10-29 · S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118.

Licence.

A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.

Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).

Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.

Natural occurrence recorded in Wikidata (LOTUS database): 107 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Indigofera hirsuta.

Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.

Manufacturing

  • ...BY CONDENSING GLYOXALINE FORMALDEHYDE WITH HIPPURIC ACID: PYMAN, J CHEM SOC 109, 186 (1916).

  • From blood corpuscles, organic synthesis

  • ISOLATED FROM BLOOD CORPUSCLES BY METHOD OF ELECTRICAL TRANSPORT... BY PRECIPITATION WITH MERCURIC CHLORIDE... CONVENIENT LAB PROCEDURES: FOSTER, SHEMIN, ORG SYN COLL VOL II, 330 (1943). SYNTHESIS BY CONDENSING 4-CHLOROMETHYLGLYOXALINE WITH ETHYLCHLOROMALONATE: PYMAN, J CHEM SOC 99, 668, 1386 (1911)...

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · The Merck Index. 9th ed. Rahway, New Jersey: Merck & Co., Inc., 1976., p. 619; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 13th ed. New York, NY: John Wiley & Sons, Inc. 1997., p. 578.

Licence.

Appearance

  • COLORLESS

  • Needles or plates

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Sax, N.I. Dangerous Properties of Industrial Materials. 5th ed. New York: Van Nostrand Rheinhold, 1979., p. 725; Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 807.

Licence.

Taste described

  • Sweet

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Budavari, S. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 1996., p. 807.

Licence.

Associated research

ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.

2026-11-01

Other names: L-histidine (French), L-histidine (English), L-Histidin (German), Histidina (Spanish), istidina (Italian), Histidina (Portuguese).

Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.

Same substance in cosmetics: HISTIDINE.

In plain words

À quoi il sert, selon les fabricants

Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Histidine) : sport (256 produits), peau (23 produits), croissance et developpement (20 produits), immunité (18 produits), antioxydant (14 produits).

Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.

Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.

What the registers say, country by country

Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.

Compl'Alim ingredient list (France): listed.

Compl'Alim, reference list of ingredients, retrieved 21 October 2026.

United States, supplement labels (DSLD; supplements need no prior approval): 248 products.

Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.

Declared daily quantities

Declared daily quantities: Histidine
UnitProductsMedianMinimumMaximum
mg1012822.0251,800

Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.

Products