L-isoleucine in food supplements
2,400 supplements declared in France contain L-isoleucine as a substance or active ingredient.
Declarations also use the name: Isoleucine. Separate page, as the form (L or D) is not always stated.
Other names in the Compl'Alim list: L-isoleucine.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 15 November 2026.
In plain words
À quoi il sert, selon les fabricants
Objectives most often stated for supplements that contain it (L-isoleucine): sport (1532 produits), croissance et developpement (79 produits), immunité (32 produits), système nerveux (32 produits), peau (28 produits).
These are the objectives manufacturers declared to the authorities, not proven effects. On the packaging, only health claims authorised by the EU may be written.
Compl'Alim, food supplement declarations (France), retrieved 15 November 2026.
What we know about this ingredient
Scientific publications (PubMed)
376 records published in the five years before 12 November 2026. The name is searched in the title or abstract; derivatives and passing mentions can be counted. This count does not measure effectiveness.
Searched on 12 November 2026.
Most recent systematic reviews and meta-analyses:
- PMID 38542319. Unmasking the Metabolite Signature of Bladder Cancer: A Systematic Review. (2024, International journal of molecular sciences)
- PMID 36495344. Multi-cohort analysis of depression-associated gut bacteria sheds insight on bacterial biomarkers across populations. (2022, Cellular and molecular life sciences : CMLS)
- PMID 33096658. The Impact of Amino Acids on Postprandial Glucose and Insulin Kinetics in Humans: A Quantitative Overview. (2020, Nutrients)
What health agencies say
An opinion says what the agency recommends; it is not a rule binding on the product.
The BfR derived, for adults, a guidance value of 2.2 g per day for isolated isoleucine (alone or with the other branched-chain amino acids) taken in addition to the normal diet. It is based on animal data with uncertainty factors.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 1146 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 2259 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Malaysia, registered products: 14 products.
NPRA, Malaysian pharmaceutical products register, retrieved 27 October 2026.
Ministry of Health Malaysia / NPRA, Pharmaceutical Products, CC BY 4.0
Taiwan, registered products: 62 products.
TFDA, Taiwan tablets, capsules and medical nutrition registers, retrieved 27 October 2026.
Taiwan Food and Drug Administration (TFDA), Open Government Data License, version 1.0
United States, supplements listed by the USDA: 25 products.
USDA FoodData Central Branded, supplement cohort, retrieved 15 November 2026.
Source: U.S. Department of Agriculture, Agricultural Research Service, FoodData Central, Branded Foods. Data published under CC0 1.0 Universal, https://creativecommons.org/publicdomain/zero/1.0/.
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