L-leucine in food supplements
3,277 supplements declared in France contain L-leucine as a substance or active ingredient.
Declarations also use the name: Leucine. Separate page, as the form (L or D) is not always stated.
Other names in the Compl'Alim list: L-leucine.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 15 November 2026.
In plain words
À quoi il sert, selon les fabricants
Objectives most often stated for supplements that contain it (L-leucine): sport (1636 produits), croissance et developpement (93 produits), immunité (66 produits), système nerveux (64 produits), antioxydant (63 produits).
These are the objectives manufacturers declared to the authorities, not proven effects. On the packaging, only health claims authorised by the EU may be written.
Compl'Alim, food supplement declarations (France), retrieved 15 November 2026.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-leucine
Searched on 1 November 2026.
Scientific publications (PubMed)
668 records published in the five years before 12 November 2026. The name is searched in the title or abstract; derivatives and passing mentions can be counted. This count does not measure effectiveness.
Searched on 12 November 2026.
Most recent systematic reviews and meta-analyses:
- PMID 42965751. Pharmacological Interventions for Neurological Manifestations of Ataxia-Telangiectasia: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials. (2026, Cerebellum (London, England))
- PMID 38345088. Nutritional interventions for preventing and treating pressure ulcers. (2024, The Cochrane database of systematic reviews)
- PMID 37692424. Impact of drought on soil microbial biomass and extracellular enzyme activity. (2023, Frontiers in plant science)
What health agencies say
An opinion says what the agency recommends; it is not a rule binding on the product.
The BfR derived, for adults, a guidance value of 4.0 g per day for isolated leucine (alone or with the other branched-chain amino acids) taken in addition to the normal diet. It is based on animal data with uncertainty factors.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 1311 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 2737 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Malaysia, registered products: 15 products.
NPRA, Malaysian pharmaceutical products register, retrieved 27 October 2026.
Ministry of Health Malaysia / NPRA, Pharmaceutical Products, CC BY 4.0
Taiwan, registered products: 52 products.
TFDA, Taiwan tablets, capsules and medical nutrition registers, retrieved 27 October 2026.
Taiwan Food and Drug Administration (TFDA), Open Government Data License, version 1.0
United States, supplements listed by the USDA: 36 products.
USDA FoodData Central Branded, supplement cohort, retrieved 15 November 2026.
Source: U.S. Department of Agriculture, Agricultural Research Service, FoodData Central, Branded Foods. Data published under CC0 1.0 Universal, https://creativecommons.org/publicdomain/zero/1.0/.
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