CI 45100
Official label name (INCI name, EU glossary of cosmetic ingredient names), No 6409
- Allowed with restrictions (Annex III)
- Colorant allowed under conditions (Annex IV)
CI 45100: Allowed with restrictions, with limits depending on the product type (Annex III, entry 193); colorant allowed under conditions, with limits depending on the product type (Annex IV, entry 71), under Regulation (EC) No 1223/2009. Annexes of the Regulation consulted on 21 October 2026.
In plain words
What it is used for
Functions declared by manufacturers:
Colorant: colours cosmetics and/or imparts colour to the skin and/or its appendages.
Hair dyeing: colours hair.
What the rules say
Allowed, with restrictions: Annex III sets a maximum concentration, the product types allowed and a warning to be printed on the packaging. Ingredient lists do not give quantities, so the concentration cannot be checked on the label; the warning can.
An ingredient can be used as a colorant only if it appears on the list of Annex IV. CI 45100 is on it with a maximum concentration.
The text of the annexes
Allowed with restrictions
This entry covers the same substance as CI 45100 (same CAS number in the CosIng inventory): its conditions apply.
| Product type | Maximum concentration | Other conditions |
|---|---|---|
| (a) Hair dye substance in oxidative hair dye products | not set | After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.5%. |
| (b) Hair dye substance in non-oxidative hair dye products | 0.6% | not set |
- Warning to print
- a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp,— you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.
- Entry
- Annex III, No 193
- Substance
- Hydrogen 3,6-bis(diethylamino)-9-(2,4-disulphonatophenyl)xanthylium, sodium salt; CI 45100 (see note 17)
- Glossary names
- ACID RED 52
- CAS
- 3520-42-1
- EC
- 222-529-8
Dates in the act (3)
- Entry into force on 15 May 2013
- Application from 11 July 2013
It shall apply from 11 July 2013.
- Entry into force on 11 July 2013
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Colorant allowed under conditions
- Maximum concentration
- Rinse-off products
- Entry
- Annex IV, No 71
- Substance
- Hydrogen 3,6-bis(diethylamino)-9-(2,4-disulphonatophenyl)xanthylium, sodium salt
- Glossary names
- CI 45100/ ACID RED 52
- CAS
- 3520-42-1
- EC
- 222-529-8
Dates in the act (10)
- Entry into force on 11 January 2010
- Application from 1 December 2010
It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
- Entry into force on 1 December 2010
- Condition applicable from 11 January 2012
As from 11 January 2012, by way of derogation from Directive 76/768/EEC, notification carried out in accordance with Article 13 of this Regulation shall be considered to comply with Article 7(3) and Article 7a(4) of that Directive
- Application from 11 January 2013
July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
- Entry into force on 11 January 2013
- Application from 11 July 2013
It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall appl
- Entry into force on 11 July 2013
- Placing on the market before 11 July 2013
Article 39 Transitional provisions By way of derogation from Directive 76/768/EEC, cosmetic products which comply with this Regulation may be placed on the market before 11 July 2013.
- Placing on the market from 11 July 2013
As from 11 July 2013, a distributor who makes available in a Member State a cosmetic product already placed on the market in another Member State and translates, on his own initiative, any element of the labelling of that product in order to comply with national law, shall submit, by electronic means, the following info
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Identity
- CosIng identifier
- 32764
- CAS (according to CosIng)
- 3520-42-1
- EC (according to CosIng)
- 222-529-8
- Declared functions
- Colorant, Hair dyeing
The CAS number cited by CosIng also covers 1 other INCI name: it designates a family of substances, not this ingredient alone.
EU product alerts (Safety Gate)
1 alert on cosmetic products cite this name in their hazard description. An alert targets a specific product, not the ingredient itself; each alert states the reason (prohibited substance, limit exceeded, missing labelling, and so on).
- 23 October 2009: Hand and body lotion - Strawberry & Milk., Sen Body Care, Finland (“Serious risk”) alert
Elsewhere in the world
Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.
United Kingdom (Great Britain)
- Allowed with restrictions (Annex III)
- Colorant allowed under conditions (Annex IV)
Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
South Korea
- Allowed colorant: 적색 106 호 (애시드레드, Acid Red)* CI 45100 (Acid Red)
색소 고시 별표 1 (allowed colorants), entry 51, page 4.
Conditions, source text, in Korean
적용 후 바로 씻어내는 제품 및 염모용 화장품에만 사용 | 비고: 타르색소
- Allowed colorant: 산성적색 52 호 (Acid Red 52) CI 45100 (Acid Red 52)
색소 고시 별표 1 (allowed colorants), entry 120, page 7. Limit: 0.6%.
Conditions, source text, in Korean
염모용 화장품에만 사용 | ◎ 사용한도 0.6% | 비고: 타르색소
Recorded cosmetics that contain it
29 recorded products list it, according to Open Beauty Facts contributors. Records are dated: the formula may have changed. See the list (in French).
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.