Compoatlas

DISPERSE BLUE 1

Official label name (INCIInternational name of cosmetic ingredients: the one printed on the pack. name, EU glossary of cosmetic ingredient names), No 9473

DISPERSE BLUE 1: Prohibited in cosmetics (Annex II, entry 700), under Regulation (EC) No 1223/2009. Good to know: classified carcinogenic (category 1B); classified as a sensitiser (skin allergy). Annexes of the Regulation consulted on 23 October 2026.

Who it concerns

This ingredient is prohibited in cosmetics in the European Union: what follows describes its hazards, not a permitted use.

What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.

Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.

  • Pregnancy and breastfeeding

    Prohibited in cosmetics in the European Union for everyone, whatever the age or situation: no specific condition is therefore needed for this group.

  • Babies and children

    Prohibited in cosmetics in the European Union for everyone, whatever the age or situation: no specific condition is therefore needed for this group.

  • Skin, eyes and allergies

    Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.

    Worth watching Classified under the CLPEU regulation that classifies chemicals by their hazards (EC No 1272/2008). Regulation: skin irritation, category 2 (Skin Irrit. 2); serious eye damage, category 1 (Eye Dam. 1); skin sensitisation, category 1 (Skin Sens. 1).

  • Environment

    No harmonised classification as hazardous to the aquatic environment, and it is not on ECHAEuropean Chemicals Agency.'s Candidate List as an endocrine disruptor for the environment.

  • Read on the label

    The Cosmetics Regulation requires no warning to be printed for this ingredient.

In plain words

What it is used for

Functions declared by manufacturers:

Hair dyeing: colours hair.

Functions declared in the CosIngThe European Commission's database of cosmetic ingredients. inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.

Definitions of functions (decision repealed on 8 May 2020, cited for information). Decision 2006/257/EC, inventory of cosmetic ingredients (definitions of functions), retrieved 22 October 2026.

What the rules say

It is prohibited to use it in a cosmetic product sold in the European Union, whatever the dose. If it appears on the ingredient list of a recent product, this needs checking: the record may be old or wrong, or the product intended for another market.

CosIng, Annex II of Regulation (EC) No 1223/2009 (prohibited substances), retrieved 23 October 2026, source updated 13 October 2026.

Hazard and risk

The CLP Regulation classifies this substance as carcinogenic, category 1B (presumed effect, established mainly from animal studies).

This classification describes what the substance can cause (a hazard), not what happens when using a product (a risk): the risk depends on the dose, the form and the route of exposure (skin, inhalation, ingestion).

Already prohibited in cosmetics (Annex II).

The text of the annexes

Prohibited in cosmetics

CosIng links the name DISPERSE BLUE 1 to this Annex II entry.

Entry
Annex II, No 700
Substance
1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1)
CAS
2475-45-8
EC
219-603-7

Regulation (EC) No 1223/2009, Annex II, entry 700. CosIng, Annex II of Regulation (EC) No 1223/2009 (prohibited substances), retrieved 23 October 2026, source updated 13 October 2026.

Entry from Regulation (EC) No 1223/2009, adopted on 30 November 2009.

SCCSEU Scientific Committee on Consumer Safety: it assesses cosmetic ingredients. opinions cited: Opinion concerning Chemical Ingredients in Cosmetic Products classified as Carcinogenic, Mutagenic or Toxic to Reproduction according to the Chemicals Directive 67/548/EECC; Opinion concerning Chemical Ingredients in Cosmetic Products classified as Carcinogenic, Mutagenic or Toxic to Reproduction according to the Chemicals Directive 67/548/EEC.

What has changed, and what will change

Dates of the texts that cover this ingredient. A text date may cover several substances: the details of each entry are below.

  1. Annex II, entry 700: introduced or replaced by Regulation (EC) No 1223/2009

  2. Annex II, entry 700: applies from this date

  3. CLP classification “Carc. 1B” applicable at the latest from this date (Regulation (EU) 2018/669)

Identity

CosIng identifier
55968
CAS (according to CosIng)
2475-45-8
EC (according to CosIng)
219-603-7
Declared functions
Hair dyeing

Classified hazard (CLP Regulation)

The harmonised classification is the one set by the European Union for the whole Union. H codes refer to the hazard statements of Annex III of Regulation (EC) No 1272/2008.

1,4,5,8-tetraaminoanthra quinone; C.I. Disperse Blue 1

Carcinogenicity, category 1B (Carc. 1B)

Hazard classes
Carcinogenicity, category 1B (Carc. 1B)
Skin irritation, category 2 (Skin Irrit. 2)
Serious eye damage, category 1 (Eye Dam. 1)
Skin sensitisation, category 1 (Skin Sens. 1)
Hazard statements
H350 H315 H318 H317

Annex VI, entry 611-032-00-5, linked by CAS 2475-45-8. Regulation (EC) No 1272/2008 (CLP), consolidated version, Annex VI table 3, retrieved 21 October 2026.

Entry introduced or replaced by Regulation (EU) 2018/669, applicable at the latest from 1 December 2019.

Elsewhere in the world

Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.

Comparison between countries

Most restrictive status in each country, and the maximum concentration cited. The details and the source of each rule follow.

Comparison between countries: DISPERSE BLUE 1
CountryRuleMaximum concentration cited
European UnionProhibited in cosmeticsnot cited
United KingdomProhibited in cosmeticsnot cited
SwitzerlandEU Regulation appliesnot cited
United States (federal)No federal rule recordednot cited
JapanNo entry in the lists recordednot cited
South KoreaProhibitednot cited
ChinaProhibitednot cited
AustraliaNo entry in the lists recordednot cited
BrazilProhibitednot cited

United Kingdom (Great Britain)

  • Prohibited in cosmetics (Annex II)

Same entries as in the European Union. Their maximum concentrations are compared in the “Comparison between countries” table; other conditions (product types, warnings) may differ.

Annexes II to VI in force. United Kingdom, Annexes II to VI of Regulation (EC) No 1223/2009 as retained and amended, retrieved 21 October 2026.

Contains public sector information licensed under the Open Government Licence v3.0.

Northern Ireland applies EU law.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

United States, 21 CFR part 700 and section 250.250 (FDA rules on cosmetic ingredients), eCFR, retrieved 21 October 2026.

The eCFR is not an official legal edition of the Code of Federal Regulations.

South Korea

  • Prohibited: 1,4,5,8-테트라아미노안트라퀴논(디스퍼스블루1) (DISPERSE BLUE 1)

    별표 1 (prohibited substances), entry 799, page 41.

South Korea, MFDS Regulation on Safety Standards for Cosmetics, Notification 2026-19, retrieved 22 October 2026.

Source: 식품의약품안전처 (MFDS), 화장품 안전기준 등에 관한 규정, via law.go.kr; table formatted by the publisher of this site.

China

  • Prohibited: 1,4,5,8-四氨基蒽醌(分散蓝 1) (1,4,5,8-Tetraaminoanthraquinone (Disperse Blue 1) (CAS No. 2475-45-8))

    表1 化妆品禁用原料目录 (prohibited substances, 2021年第74号), entry 29, page 附件2 (.doc) table row 29 ; TID reprint p.3.

China, NMPA catalogues of prohibited cosmetic ingredients (2021 No. 74, revised up to 2026), retrieved 22 October 2026.

Source: 国家药品监督管理局 (NMPA); plant catalogue as reprinted by the Trade and Industry Department of Hong Kong; table formatted by the publisher of this site.

Brazil

  • Prohibited: 1,4,5,8-tetraaminoantraquinona, (Azul Disperso 1), com exceção para uso em tinturas capilares em concentrações até 1%

    RDC 529/2021, Anexo (prohibited substances), entry 700, page 25.

    Conditions, source text, in Portuguese

    N° UE: 700

Brazil, ANVISA resolutions RDC 529/2021, 528/2021, 600/2022 and 628/2022, retrieved 22 October 2026.

Source: ANVISA. Text of the adopted draft resolutions, as the Official Journal could not be accessed; the 2021 lists of prohibited substances and preservatives were compared with the copy of the published text distributed by the State of Paraná, the 2022 lists of UV filters and colorants were not.

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 23 October 2026.

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