GLYOXAL
Official label name (INCI name, EU glossary of cosmetic ingredient names), No 11380
- Allowed with restrictions (Annex III)
GLYOXAL: Allowed with restrictions, with limits depending on the product type (Annex III, entry 194), under Regulation (EC) No 1223/2009.
In plain words
What it is used for
Functions declared by manufacturers:
Antimicrobial: helps control the growth of micro-organisms on the skin.
Perfuming.
What the rules say
Allowed, with restrictions: Annex III sets a maximum concentration. Ingredient lists do not give quantities, so the concentration cannot be checked on the label.
Hazard and risk
The CLP Regulation classifies this substance as mutagenic (may damage DNA), category 2 (suspected effect, without enough evidence for a higher category).
This classification describes what the substance can cause (a hazard), not what happens when using a product (a risk): the risk depends on the dose, the form and the route of exposure (skin, inhalation, ingestion).
Classified as a category 2 CMR and allowed under the conditions of Annex III, after an SCCS assessment.
The text of the annexes
Allowed with restrictions
- Maximum concentration
- 100 mg/kg
- Entry
- Annex III, No 194
- Substance
- Glyoxal
- Glossary names
- GLYOXAL
- CAS
- 107-22-2
- EC
- 203-474-9
Dates in the act (3)
- Entry into force on 15 May 2013
- Application from 11 July 2013
It shall apply from 11 July 2013.
- Entry into force on 11 July 2013
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Identity
- CosIng identifier
- 34157
- CAS (according to CosIng)
- 107-22-2
- EC (according to CosIng)
- 203-474-9
- Declared functions
- Antimicrobial, Perfuming
- Wikidata
- Q413465
- PubChem
- 7860
- ECHA InfoCard
- 100.003.160
- InChIKey
- LEQAOMBKQFMDFZ-UHFFFAOYSA-N
Classified hazard (CLP Regulation)
The harmonised classification is the one set by the European Union for the whole Union. H codes refer to the hazard statements of Annex III of Regulation (EC) No 1272/2008.
glyoxal…%; ethandial…%
CMR Muta. 2
- Hazard classes
- Muta. 2
Acute Tox. 4 *
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1 - Hazard statements
- H341 H332 H319 H315 H317
- CLP notes
- B
Elsewhere in the world
Information on other jurisdictions. What is covered, and what is not yet.
United Kingdom (Great Britain)
- Allowed with restrictions (Annex III)
Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
South Korea
- Restricted: 글라이옥살 (GLYOXAL)
별표 2, 기타 (other substances with limits), entry 4, page 27. Limit: 0.01%.
Recorded cosmetics that contain it
5 recorded products list it, according to Open Beauty Facts contributors. Records are dated: the formula may have changed. See the list (page in French).
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.