Compoatlas

HC BLUE NO. 2

Official label name (INCIInternational name of cosmetic ingredients: the one printed on the pack. name, EU glossary of cosmetic ingredient names), No 11578

HC BLUE NO. 2: Allowed with restrictions, maximum 2.8% in the ready-for-use preparation, only in: Hair dye substance in non-oxidative hair dye products (Annex III, entry 247), under Regulation (EC) No 1223/2009. Annexes of the Regulation consulted on 23 October 2026.

Who it concerns

What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.

Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.

  • Pregnancy and breastfeeding

    No classification harmonised by the European Union covers reproduction, the unborn child or breastfeeding for this substance. This does not mean it has been judged to have no effect during pregnancy.

  • Babies and children

    The Cosmetics Regulation sets no age-related condition for this ingredient.

  • Skin, eyes and allergies

    No official classification for sensitisation, irritation or eye damage, and no obligation to label it as an allergen.

  • Environment

    No harmonised classification as hazardous to the aquatic environment, and it is not on ECHAEuropean Chemicals Agency.'s Candidate List as an endocrine disruptor for the environment.

  • Read on the label

    For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.

    For information Annex III, entry 247, requires this to be printed on the pack: “Can cause allergic reaction”.

CosIng, Annex III of Regulation (EC) No 1223/2009 (restricted substances), retrieved 23 October 2026, source updated 13 October 2026.

In plain words

What it is used for

Functions declared by manufacturers:

Hair dyeing: colours hair.

Functions declared in the CosIngThe European Commission's database of cosmetic ingredients. inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.

Definitions of functions (decision repealed on 8 May 2020, cited for information). Decision 2006/257/EC, inventory of cosmetic ingredients (definitions of functions), retrieved 22 October 2026.

What the rules say

Allowed, with restrictions: Annex III sets a maximum concentration, the product types allowed and a warning to be printed on the packaging. Ingredient lists do not give quantities, so the concentration cannot be checked on the label; the warning can.

CosIng, Annex III of Regulation (EC) No 1223/2009 (restricted substances), retrieved 23 October 2026, source updated 13 October 2026.

The text of the annexes

Allowed with restrictions

Product type
Hair dye substance in non-oxidative hair dye products
Maximum concentration
2.8%
Other conditions
- Do not use nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers
Warning to print
Can cause allergic reaction
Entry
Annex III, No 247
Substance
2,2'-[[4-[(2-Hydroxyethyl)amino]-3-nitrophenyl]imino]bisethanol (see note 17)
Glossary names
HC BLUE NO 2
CAS
33229-34-4
EC
251-410-3
Dates in the act (2)
  • Entry into force on 15 May 2013
  • Application from 11 July 2013
    It shall apply from 11 July 2013.

Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.

Regulation (EC) No 1223/2009, Annex III, entry 247. CosIng, Annex III of Regulation (EC) No 1223/2009 (restricted substances), retrieved 23 October 2026, source updated 13 October 2026.

Entry from Regulation (EU) n° 344/2013, adopted on 4 April 2013.

SCCSEU Scientific Committee on Consumer Safety: it assesses cosmetic ingredients. opinions cited: Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic Products; Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004; Opinion on Personal Use of Hair Dyes and Cancer Risk; Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk; Assessment Strategies for Hair Dyes; Opinion on HC Blue No. 2.

What has changed, and what will change

Dates of the texts that cover this ingredient. A text date may cover several substances: the details of each entry are below.

  1. Annex III, entry 247: introduced or replaced by Regulation (EU) n° 344/2013

  2. Annex III, entry 247: applies from this date

Identity

CosIng identifier
34191
CAS (according to CosIng)
33229-34-4
EC (according to CosIng)
251-410-3
Declared functions
Hair dyeing
Wikidata
Q27155970
PubChem
36383
ECHA InfoCard
100.046.722
InChIKey
MIWUTEVJIISHCP-UHFFFAOYSA-N

CosIng inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.

Wikidata, items with a CosIng identifier (P3073), retrieved 22 October 2026.

Wikidata, PubChem and ECHA links are published only when verified: same CosIng identifier, a single item, matching CAS number.

Elsewhere in the world

Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.

Comparison between countries

Most restrictive status in each country, and the maximum concentration cited. The details and the source of each rule follow.

CountryRuleMaximum concentration cited
European UnionAllowed with restrictions2.8%
United KingdomAllowed with restrictions2.8%
SwitzerlandEU Regulation applies2.8%
United States (federal)No federal rule recordednot cited
JapanNo entry in the lists recordednot cited
South KoreaProhibited differs from the EU2.8%
ChinaNot on the prohibited lists recorded (lists of allowed substances are not recorded)not cited
AustraliaNo entry in the lists recordednot cited
BrazilNo entry in the lists recordednot cited

United Kingdom (Great Britain)

  • Allowed with restrictions (Annex III)

Same entries as in the European Union. Their maximum concentrations are compared in the “Comparison between countries” table; other conditions (product types, warnings) may differ.

Annexes II to VI in force. United Kingdom, Annexes II to VI of Regulation (EC) No 1223/2009 as retained and amended, retrieved 21 October 2026.

Contains public sector information licensed under the Open Government Licence v3.0.

Northern Ireland applies EU law.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

United States, 21 CFR part 700 and section 250.250 (FDA rules on cosmetic ingredients), eCFR, retrieved 21 October 2026.

The eCFR is not an official legal edition of the Code of Federal Regulations.

South Korea

  • Prohibited: 2,2'-[[4-[(2-하이드록시에칠)아미 노]-3-니트로페닐]이미노]비스에탄올 및 그 염류(예 : 에이치시 청색 No. 2)

    별표 1 (prohibited substances), entry 1028, page 52.

    Conditions, source text, in Korean

    화학물질명: 에이치시 청색No.2 (CAS No. 33229-34-4) | ※ 유의사항 2: 1) 표시는 [별표 2] 염모제 성분에서 정한 기준에 적합한 경우는 제외한다.

  • Restricted: 2,2'-[[4-[(2-하이드록시에칠)아미노]-3-니트로페 닐]이미노]비스에탄올 및 그 염류 (HC BLUE NO 2)

    별표 2, 염모제 성분 (hair colorants), entry 72, page 25. Limit: 비산화염모제에 2.8%.

    Conditions, source text, in Korean

    비고: 기타제품에는 사용금지 | 화학물질명: 에이치시 청색No.2 (CAS No. 33229-34-4)

South Korea, MFDS Regulation on Safety Standards for Cosmetics, Notification 2026-19, retrieved 22 October 2026.

Source: 식품의약품안전처 (MFDS), 화장품 안전기준 등에 관한 규정, via law.go.kr; table formatted by the publisher of this site.

Recorded cosmetics that contain it

1 recorded product list it, according to Open Beauty Facts contributors. Records are dated: the formula may have changed. See the list (in French).

Open Beauty Facts, export of cosmetic products, retrieved 23 October 2026.

Data “Open Beauty Facts and its contributors”, licensed under ODbL 1.0 (opendatacommons.org/licenses/odbl/1-0); derived table distributed under the same licence.

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 23 October 2026.