HC ORANGE NO. 2
Official label name (INCIInternational name of cosmetic ingredients: the one printed on the pack. name, EU glossary of cosmetic ingredient names), No 11591
- Allowed with restrictions (Annex III)
HC ORANGE NO. 2: Allowed with restrictions, maximum 1.0% in the ready-for-use preparation, only in: Hair dye substance in non-oxidative hair dye products (Annex III, entry 208), under Regulation (EC) No 1223/2009. Annexes of the Regulation consulted on 21 October 2026.
Who it concerns
What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.
Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.
Pregnancy and breastfeeding
No classification harmonised by the European Union covers reproduction, the unborn child or breastfeeding for this substance. This does not mean it has been judged to have no effect during pregnancy.
Babies and children
The Cosmetics Regulation sets no age-related condition for this ingredient.
Skin, eyes and allergies
No official classification for sensitisation, irritation or eye damage, and no obligation to label it as an allergen.
Environment
No harmonised classification as hazardous to the aquatic environment, and it is not on ECHAEuropean Chemicals Agency.'s Candidate List as an endocrine disruptor for the environment.
Read on the label
For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.
For information Annex III, entry 208, requires this to be printed on the pack: “Hair colorants can cause severe allergic reactions. Read and follow instructions. .”.
CosIng, Annex III of Regulation (EC) No 1223/2009 (restricted substances), retrieved 21 October 2026, source updated 13 October 2026.
In plain words
What it is used for
Functions declared by manufacturers:
Hair dyeing: colours hair.
Functions declared in the CosIngThe European Commission's database of cosmetic ingredients. inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.
Definitions of functions (decision repealed on 8 May 2020, cited for information). Decision 2006/257/EC, inventory of cosmetic ingredients (definitions of functions), retrieved 22 October 2026.
What the rules say
Allowed, with restrictions: Annex III sets a maximum concentration, the product types allowed and a warning to be printed on the packaging. Ingredient lists do not give quantities, so the concentration cannot be checked on the label; the warning can.
CosIng, Annex III of Regulation (EC) No 1223/2009 (restricted substances), retrieved 21 October 2026, source updated 13 October 2026.
The text of the annexes
Allowed with restrictions
- Product type
- Hair dye substance in non-oxidative hair dye products
- Maximum concentration
- 1.0%
- Other conditions
- - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitritefree containes
- Warning to print
- Hair colorants can cause severe allergic reactions. Read and follow instructions. .
- Entry
- Annex III, No 208
- Substance
- 1-(beta-Aminoethyl)amino-4-(beta-hydroxyethyl)oxy-2-nitrobenzene and its salts
- Glossary names
- HC ORANGE NO. 2
- CAS
- 85765-48-6
- EC
- 416-410-1
Dates in the act (2)
- Entry into force on 15 May 2013
- Application from 11 July 2013
It shall apply from 11 July 2013.
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Regulation (EC) No 1223/2009, Annex III, entry 208. CosIng, Annex III of Regulation (EC) No 1223/2009 (restricted substances), retrieved 21 October 2026, source updated 13 October 2026.
Entry from Regulation (EU) n° 344/2013, adopted on 4 April 2013.
SCCSEU Scientific Committee on Consumer Safety: it assesses cosmetic ingredients. opinions cited: Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic Products; Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004; Opinion on Personal Use of Hair Dyes and Cancer Risk; Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk; Assessment Strategies for Hair Dyes; Memorandum on Hair Dye Substances and their Skin Sensitising Properties; Opinion on HC Orange No. 2.
What has changed, and what will change
Dates of the texts that cover this ingredient. A text date may cover several substances: the details of each entry are below.
Annex III, entry 208: introduced or replaced by Regulation (EU) n° 344/2013
Annex III, entry 208: applies from this date
Identity
CosIng inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.
Wikidata, items with a CosIng identifier (P3073), retrieved 22 October 2026.
Wikidata, PubChem and ECHA links are published only when verified: same CosIng identifier, a single item, matching CAS number.
Elsewhere in the world
Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.
Comparison between countries
Most restrictive status in each country, and the maximum concentration cited. The details and the source of each rule follow.
| Country | Rule | Maximum concentration cited |
|---|---|---|
| European Union | Allowed with restrictions | 1% |
| United Kingdom | Allowed with restrictions | 1% |
| Switzerland | EU Regulation applies | 1% |
| United States (federal) | No federal rule recorded | not cited |
| Japan | No entry in the lists recorded | not cited |
| South Korea | Prohibited differs from the EU | 1% |
| China | Not on the prohibited lists recorded (lists of allowed substances are not recorded) | not cited |
| Australia | No entry in the lists recorded | not cited |
| Brazil | No entry in the lists recorded | not cited |
United Kingdom (Great Britain)
- Allowed with restrictions (Annex III)
Same entries as in the European Union. Their maximum concentrations are compared in the “Comparison between countries” table; other conditions (product types, warnings) may differ.
Annexes II to VI in force. United Kingdom, Annexes II to VI of Regulation (EC) No 1223/2009 as retained and amended, retrieved 21 October 2026.
Contains public sector information licensed under the Open Government Licence v3.0.
Northern Ireland applies EU law.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
Switzerland, FDHA Ordinance on Cosmetic Products (OCos, SR 817.023.31), consolidated version, retrieved 22 October 2026.
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
United States, 21 CFR part 700 and section 250.250 (FDA rules on cosmetic ingredients), eCFR, retrieved 21 October 2026.
The eCFR is not an official legal edition of the Code of Federal Regulations.
South Korea
- Prohibited: 1-(2-아미노에칠)아미노-4-(2-하이드록시에칠)옥시-2-니트로벤젠 및 그 염류 (예 : 에이치시 등색 No. 2)
별표 1 (prohibited substances), entry 511, page 27.
Conditions, source text, in Korean
화학물질명: 1-(2-아미노에칠)아미노-4-(2-하이드록시에칠)옥시-2-니트로벤젠 (에이치시 등색 No. 2) (CAS No. 85765-48-6) | ※ 유의사항 2: 1) 표시는 [별표 2] 염모제 성분에서 정한 기준에 적합한 경우는 제외한다.
- Restricted: 1-(2-아미노에칠)아미노-4-(2-하이드록시에칠)옥시-2-니트로벤젠 및 그 염류 (HC ORANGE NO 2)
별표 2, 염모제 성분 (hair colorants), entry 64, page 24. Limit: 비산화염모제에 1.0%.
Conditions, source text, in Korean
비고: 기타제품에는 사용금지 | 화학물질명: 에이치시 등색No.2 (CAS No. 85765-48-6)
South Korea, MFDS Regulation on Safety Standards for Cosmetics, Notification 2026-19, retrieved 22 October 2026.
Source: 식품의약품안전처 (MFDS), 화장품 안전기준 등에 관한 규정, via law.go.kr; table formatted by the publisher of this site.
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.