Compoatlas

HYDROXYETHYL-2-NITRO-P-TOLUIDINE

Official label name (INCI name, EU glossary of cosmetic ingredient names), No 13274

HYDROXYETHYL-2-NITRO-P-TOLUIDINE: Allowed with restrictions, with limits depending on the product type (Annex III, entry 221), under Regulation (EC) No 1223/2009.

In plain words

What it is used for

Functions declared by manufacturers:

Hair dyeing: colours hair.

What the rules say

Allowed, with restrictions: Annex III sets a maximum concentration, the product types allowed and a warning to be printed on the packaging. Ingredient lists do not give quantities, so the concentration cannot be checked on the label; the warning can.

The text of the annexes

Allowed with restrictions

Entry
Annex III, No 221
Substance
2-(4-Methyl-2-nitroanilino)ethanol
Glossary names
Hydroxyethyl-2-Nitro-p-Toluidine
CAS
100418-33-5
EC
408-090-7
Product type
(a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
Maximum concentration
(b) 1,0%
Other conditions
(a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,0% For (a) and (b): - Do not use with nitrosating agents - Maximum nitrosamine content 50 microgram/Kg - Keep in nitrite-free containers
Warnings
To be printed on the label: Hair colorants can use severe allergic reactions
Dates in the act (4)
  • Application from 11 July 2013
    etic products (1), and in particular Article 31(1) thereof, Whereas: (1) Regulation (EC) No 1223/2009 replacing Council Directive 76/768/EEC of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products (2) will apply from 11 July 2013.
  • Entry into force on 31 July 2013
  • Application from 1 September 2013
    It shall apply from 1 September 2013.
  • Entry into force on 1 September 2013

Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.

Identity

CosIng identifier
34508
CAS (according to CosIng)
100418-33-5
EC (according to CosIng)
408-090-7
Declared functions
Hair dyeing
Wikidata
Q27282317
PubChem
10130360
ECHA InfoCard
100.100.952
InChIKey
SCZQUWZLEIYDBD-UHFFFAOYSA-N

Elsewhere in the world

Information on other jurisdictions. What is covered, and what is not yet.

United Kingdom (Great Britain)

  • Allowed with restrictions (Annex III)

Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

South Korea

  • Prohibited: 1-메칠-3-니트로-4-(베타-하이드록시에칠)아미노벤젠 및 그 염류(예 : 하이드록시에칠-2-니트로-p-톨루이딘)

    별표 1 (prohibited substances), entry 236, page 12. Conditions (source text, in Korean): 화학물질명: 하이드록시에칠-2-니트로-p-톨루이딘 (CAS No. 100418-33-5) | ※ 유의사항 2: 1) 표시는 [별표 2] 염모제 성분에서 정한 기준에 적합한 경우는 제외한다.

  • Restricted: 하이드록시에칠-2-니트로-p-톨루이딘

    별표 2, 염모제 성분 (hair colorants), entry 50, page 21. Limit: 1.0%. Conditions (source text, in Korean): 비고: 기타제품에는 사용금지

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.