HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE
Official label name (INCIInternational name of cosmetic ingredients: the one printed on the pack. name, EU glossary of cosmetic ingredient names), No 13285
- Prohibited in cosmetics (Annex II)
HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE: Prohibited in cosmetics (Annex II, entry 1380), under Regulation (EC) No 1223/2009. Good to know: classified as a sensitiser (skin allergy). Annexes of the Regulation consulted on 23 October 2026.
Who it concerns
This ingredient is prohibited in cosmetics in the European Union: what follows describes its hazards, not a permitted use.
What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.
Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.
Pregnancy and breastfeeding
Prohibited in cosmetics in the European Union for everyone, whatever the age or situation: no specific condition is therefore needed for this group.
Babies and children
Prohibited in cosmetics in the European Union for everyone, whatever the age or situation: no specific condition is therefore needed for this group.
Skin, eyes and allergies
Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.
Worth watching Classified under the CLPEU regulation that classifies chemicals by their hazards (EC No 1272/2008). Regulation: skin sensitisation, category 1A (Skin Sens. 1A).
Environment
No harmonised classification as hazardous to the aquatic environment, and it is not on ECHAEuropean Chemicals Agency.'s Candidate List as an endocrine disruptor for the environment.
Read on the label
The Cosmetics Regulation requires no warning to be printed for this ingredient.
Regulation (EC) No 1272/2008 (CLP), consolidated version, Annex VI table 3, retrieved 21 October 2026.
In plain words
What it is used for
Functions declared by manufacturers:
Fragrance.
Perfuming.
Functions declared in the CosIngThe European Commission's database of cosmetic ingredients. inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.
Definitions of functions (decision repealed on 8 May 2020, cited for information). Decision 2006/257/EC, inventory of cosmetic ingredients (definitions of functions), retrieved 22 October 2026.
What the rules say
It is prohibited to use it in a cosmetic product sold in the European Union, whatever the dose. If it appears on the ingredient list of a recent product, this needs checking: the record may be old or wrong, or the product intended for another market.
CosIng, Annex II of Regulation (EC) No 1223/2009 (prohibited substances), retrieved 23 October 2026, source updated 13 October 2026.
Origin and odour
Present in 0.7% of recorded cosmetics (139 out of 20 527), mainly: shower gels, eaux de toilette.
Open Beauty Facts, export of cosmetic products, retrieved 23 October 2026.
Data “Open Beauty Facts and its contributors”, licensed under ODbL 1.0 (opendatacommons.org/licenses/odbl/1-0); derived table distributed under the same licence.
The text of the annexes
Prohibited in cosmetics
CosIng links the name HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE to this Annex II entry.
- Entry
- Annex II, No 1380
- Substance
- 3 and 4-(4-Hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde A
- CAS
- 31906-04-4 / 51414-25-6
- EC
- 250-863-4 / 257-187-9
Dates in the act (3)
- Entry into force on 23 August 2017
- Placing on the market from 23 August 2019
From 23 August 2019 cosmetic products containing that substance shall not be placed on the Union market
- Making available from 23 August 2021
From 23 August 2021 cosmetic products containing that substance shall not be made available on the Union market
Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.
Regulation (EC) No 1223/2009, Annex II, entry 1380. CosIng, Annex II of Regulation (EC) No 1223/2009 (prohibited substances), retrieved 23 October 2026, source updated 13 October 2026.
Entry from Regulation (EU) 2017/1410, adopted on 2 August 2017.
SCCSEU Scientific Committee on Consumer Safety: it assesses cosmetic ingredients. opinions cited: Opinion on Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde (Lyral); Opinion on Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde (Lyral); Opinion concerning Essential Oils; Opinion concerning Fragrance Allergy in Consumers - A Review of the Problem - Analysis of the need for appropriate Consumer Information and Identification of Consumer Allergens; Opinion concerning the Interim Position on Fragrance Allergy; Memorandum on the SCCNFP Opinion concerning Fragrance Allergy.
What has changed, and what will change
Dates of the texts that cover this ingredient. A text date may cover several substances: the details of each entry are below.
Annex II, entry 1380: introduced or replaced by Regulation (EU) 2017/1410
CLP classification “Skin Sens. 1A” applicable at the latest from this date (Regulation (EU) 2016/1179)
Annex II, entry 1380: a new product that does not comply can no longer be placed on the market
Annex II, entry 1380: a product that does not comply can no longer be sold, even from stock
Identity
- CosIng identifier
- 41531
- CAS (according to CosIng)
- 31906-04-4, 51414-25-6
- EC (according to CosIng)
- 250-863-4, 257-187-9
- Declared functions
- Fragrance, Perfuming
- Wikidata
- Q5955634
- ECHA InfoCard
- 100.046.225
CosIng cites 2 CAS numbers for this name: it covers several substances.
CosIng inventory. CosIng, inventory of cosmetic ingredients (INCI names, CAS, EC, functions), retrieved 21 October 2026.
Wikidata, items with a CosIng identifier (P3073), retrieved 22 October 2026.
Wikidata, PubChem and ECHA links are published only when verified: same CosIng identifier, a single item, matching CAS number.
Classified hazard (CLP Regulation)
The harmonised classification is the one set by the European Union for the whole Union. H codes refer to the hazard statements of Annex III of Regulation (EC) No 1272/2008.
hydroxyisohexyl 3-cyclohexene carboxaldehyde (INCI); reaction mass of 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde and 3-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde; [1] 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde; [2] 3-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde [3]
Neither carcinogenic, mutagenic nor toxic for reproduction under the harmonised classification
- Hazard classes
- Skin sensitisation, category 1A (Skin Sens. 1A)
- Hazard statements
- H317
Annex VI, entry 605-040-00-8, linked by CAS 31906-04-4. Regulation (EC) No 1272/2008 (CLP), consolidated version, Annex VI table 3, retrieved 21 October 2026.
Entry introduced or replaced by Regulation (EU) 2016/1179, applicable at the latest from 1 March 2018.
EU product alerts (Safety Gate)
135 alerts on cosmetic products cite this name in their hazard description. An alert targets a specific product, not the ingredient itself. Under each alert, its reason (prohibited substance, limit exceeded, missing labelling, and so on), as published.
The 10 most recent are listed below. All alerts.
- 16 October 2026: Body spray, Lithuania (“Serious risk”) alert
The product contains hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC), which is prohibited in cosmetic products. HICC may cause an allergic skin reaction. The product does not comply with the Cosmetic Products Regulation. - 16 October 2026: Body spray, Lithuania (“Serious risk”) alert
The product contains hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC), which is prohibited in cosmetic products. HICC may cause an allergic skin reaction. The product does not comply with the Cosmetic Products Regulation - 12 June 2026: Eau de toilette, Calvin Klein, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin…
7 other alerts
- 12 June 2026: Eau de toilette, Ben Sherman, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin… - 12 June 2026: Eau de toilette, Beyonce, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin… - 12 June 2026: Eau de toilette, Calvin Klein, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin… - 12 June 2026: Eau de toilette, Davidoff, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin… - 12 June 2026: Eau de toilette, Davidoff, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin… - 12 June 2026: Eau de toilette, Fcuk, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin… - 12 June 2026: Eau de toilette, Fcuk, United Kingdom in respect of Northern Ireland (“Serious risk”) alert
According to the list of ingredients, the product contains 2-(4-tert-butylbenzyl) propionaldehyde (BMHCA), which is prohibited in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin…
Safety Gate, EU rapid alert system for dangerous non-food products: cosmetic alerts from the weekly reports, retrieved 23 October 2026.
Source: European Commission, Safety GateEU rapid alert system for dangerous non-food products. weekly reports (CC0).
Elsewhere in the world
Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.
Comparison between countries
Most restrictive status in each country, and the maximum concentration cited. The details and the source of each rule follow.
| Country | Rule | Maximum concentration cited |
|---|---|---|
| European Union | Prohibited in cosmetics | not cited |
| United Kingdom | Prohibited in cosmetics | not cited |
| Switzerland | EU Regulation applies | not cited |
| United States (federal) | No federal rule recorded | not cited |
| Canada | No entry in the lists recorded | not cited |
| Japan | No entry in the lists recorded | not cited |
| South Korea | Prohibited | not cited |
| China | Prohibited | not cited |
| Australia | No entry in the lists recorded | not cited |
| ASEAN | Prohibited | not cited |
| Taiwan | Prohibited | not cited |
| Brazil | Prohibited | not cited |
United Kingdom (Great Britain)
- Prohibited in cosmetics (Annex II)
- Allowed with restrictions (Annex III)
Entry 79 of Annex III exists only in British law.
Annexes II to VI in force. United Kingdom, Annexes II to VI of Regulation (EC) No 1223/2009 as retained and amended, retrieved 21 October 2026.
Contains public sector information licensed under the Open Government Licence v3.0.
Northern Ireland applies EU law.
Switzerland
Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).
Switzerland, FDHA Ordinance on Cosmetic Products (OCos, SR 817.023.31), consolidated version, retrieved 22 October 2026.
United States, federal rules
None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.
United States, 21 CFR part 700 and section 250.250 (FDA rules on cosmetic ingredients), eCFR, retrieved 21 October 2026.
The eCFR is not an official legal edition of the Code of Federal Regulations.
South Korea
- Prohibited: 하이드록시아이소헥실 3-사이클로헥센카보스알데히드(HICC)
별표 1 (prohibited substances), entry 1020, page 51.
South Korea, MFDS Regulation on Safety Standards for Cosmetics, Notification 2026-19, retrieved 22 October 2026.
Source: 식품의약품안전처 (MFDS), 화장품 안전기준 등에 관한 규정, via law.go.kr; table formatted by the publisher of this site.
China
- Prohibited: 新铃兰醛（3- 和4-（4-羟基-4-甲基戊基）-3-环己烯-1-甲醛） (3-and 4-（4-Hydroxy-4-methylpentyl） cyclohex-3-ene-1-carbaldehyde （HICC） （CAS No. 51414-25-6 / CAS No. 31906-04-4）)
表1 化妆品禁用原料目录 (prohibited substances, 2021年第74号), entry 1264, page 附件2 (.doc) table row 1264 ; TID reprint p.47.
China, NMPA catalogues of prohibited cosmetic ingredients (2021 No. 74, revised up to 2026), retrieved 22 October 2026.
Source: 国家药品监督管理局 (NMPA); plant catalogue as reprinted by the Trade and Industry Department of Hong Kong; table formatted by the publisher of this site.
ASEAN (South-East Asia)
- Prohibited: 3- and 4-(4-Hydroxy-4-methylpentyl) cyclohex-3-ene-1-carbaldehyde (HICC)
Annex II (prohibited substances), entry 1380, page 64.
ASEAN Cosmetic Directive, Annexes II, III, IV, VI and VII (version 2026-1 of 22 June 2026, Annex VII 2025-2), retrieved 24 October 2026.
Source: ASEAN Cosmetic Documents, Annexes of the ASEAN Cosmetic Directive, as published by the Health Sciences Authority (HSA, Singapore); table extracted and formatted by the publisher of this site, with no endorsement by HSA or ASEAN.
Taiwan
- Prohibited: 3- and 4-(4-Hydroxy-4-methylpentyl) cyclohex-3-ene-1-carbaldehyde (HICC)
化粧品禁止使用成分表 (prohibited substances).
Taiwan, TFDA cosmetic ingredient tables (prohibited, restricted, preservatives, UV filters, colorants), open data, retrieved 24 October 2026.
Source: Taiwan Food and Drug Administration (TFDA), open datasets on data.gov.tw (Open Government Data License, version 1.0); table formatted by the publisher of this site.
Brazil
- Prohibited: Hidroxiisoexil 3-cicloexeno carboxaldeído (HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE (Hydroxymethylpentylcyclohexenecarboxaldehyde)) (HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE (Hydroxymethylpentylcyclohexenecarboxaldehyde))
RDC 529/2021, Anexo (prohibited substances): inclusões by RDC 1.030/2026, Art. 2º, entry 1417, page 5.
Conditions, source text, in Portuguese
Nº UE: 1380
Brazil, ANVISA resolutions RDC 529/2021, 528/2021, 600/2022 and 628/2022, retrieved 22 October 2026.
Source: ANVISA. Text of the adopted draft resolutions, as the Official Journal could not be accessed; the 2021 lists of prohibited substances and preservatives were compared with the copy of the published text distributed by the State of Paraná, the 2022 lists of UV filters and colorants were not.
Recorded cosmetics that contain it
139 recorded products list it, according to Open Beauty Facts contributors. Records are dated: the formula may have changed. See the list (in French).
Open Beauty Facts, export of cosmetic products, retrieved 23 October 2026.
Data “Open Beauty Facts and its contributors”, licensed under ODbL 1.0 (opendatacommons.org/licenses/odbl/1-0); derived table distributed under the same licence.
Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 23 October 2026.