P-CHLORO-M-CRESOL (chlorocresol)

What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.

Prohibition or serious classificationThe text prohibits the substance for this use, or ranks it among the most serious hazards (known or presumed carcinogenic, mutagenic or reprotoxic, identified endocrine disruptor).Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.For informationOfficial information with no condition on a finished product: warning to read, irritation of the pure substance.

• Pregnancy and breastfeeding

  No classification harmonised by the European Union covers reproduction, the unborn child or breastfeeding for this substance. This does not mean it has been judged to have no effect during pregnancy.

• Babies and children

  The Cosmetics Regulation sets no age-related condition for this ingredient.

• Skin, eyes and allergies

  Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.

  Worth watching Classified under the CLPEU regulation that classifies chemicals by their hazards (EC No 1272/2008). Regulation: skin corrosion, category 1C (Skin Corr. 1C); serious eye damage, category 1 (Eye Dam. 1); skin sensitisation, category 1B (Skin Sens. 1B).

• Environment

  Worth watchingThe text sets a condition or flags a hazard worth knowing: allergen, suspected effect, condition for children, hazard to the aquatic environment.

  Worth watching Classified under the CLP Regulation: hazardous to the aquatic environment, short term, category 1 (Aquatic Acute 1); hazardous to the aquatic environment, long term, category 3 (Aquatic Chronic 3).

• Read on the label

  The Cosmetics Regulation requires no warning to be printed for this ingredient.

Preservative allowed under conditions

Product type

Not to be used in products applied on mucous membranes

Maximum concentration

0.2%

Entry

Annex V, No 24

Substance

Chlorocresol

Glossary names

P-CHLORO-M-CRESOL

CAS

59-50-7

EC

200-431-6

Identity

CosIng identifier

35870

CAS (according to CosIng)

59-50-7

EC (according to CosIng)

200-431-6

Declared functions

Antimicrobial, Preservative

Wikidata

Q302865

PubChem

1732

ECHA InfoCard

100.000.392

InChIKey

CFKMVGJGLGKFKI-UHFFFAOYSA-N

chlorocresol; 4-chloro-m-cresol; 4-chloro-3-methylphenol

Neither carcinogenic, mutagenic nor toxic for reproduction under the harmonised classification

Hazard classes

Acute toxicity, category 4 (Acute Tox. 4)
Skin corrosion, category 1C (Skin Corr. 1C)
Serious eye damage, category 1 (Eye Dam. 1)
Specific target organ toxicity, single exposure, category 3 (STOT SE 3)
Skin sensitisation, category 1B (Skin Sens. 1B)
Hazardous to the aquatic environment, short term, category 1 (Aquatic Acute 1)
Hazardous to the aquatic environment, long term, category 3 (Aquatic Chronic 3)

Hazard statements

H302 H314 H318 H335 H317 H400 H412

• 23 December 2022: Shower gel, MEGLIO SFUSO, Slovakia (“Serious risk”) alert
  According to the list of ingredients, the product contains butylphenyl methylpropional (BMHCA) which is forbidden in cosmetic products. BMHCA may harm the reproductive system, may harm the health of the unborn child and may cause skin sensitisation.…

United Kingdom (Great Britain)

• Preservative allowed under conditions (Annex V)

Same entries as in the European Union. Their maximum concentrations are compared in the “Comparison between countries” table; other conditions (product types, warnings) may differ.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

Canada

• Restricted (conditions or maximum concentration): p-Chloro-m-crésol (p-Chloro-m-cresol)

  Hotlist, restricted ingredients. a) Not permitted in cosmetics intended to be used on or around mucosal membranes such as eyes, mouth or nose | b) Other cosmetics: maximum concentration 0.1% | Synonyms and related compounds: Chlorocresol

South Korea

• Restricted: p-클로로-m-크레졸

  별표 2, 보존제 성분 (preservatives), entry 42, page 10. Limit: 0.04%.

  Conditions, source text, in Korean

  비고: 점막에 사용되는 제품에는 사용금지

ASEAN (South-East Asia)

• Allowed preservative: 4-Chloro-m-cresol

  Annex VI (allowed preservatives), entry 24, page 272. Limit: 0.2%.

  Conditions, source text

  Limitations and requirements: Prohibited in products intended to come into contact with mucous membranes

Taiwan

• Allowed preservative: Chlorocresol (p-Chloro-m-cresol)

  化粧品防腐劑成分名稱及使用限制表 (allowed preservatives). Limit: 0.2%.

  Conditions, source text, in Chinese

  限制規定：不得使用於接觸黏膜部位產品。

Brazil

• Allowed under conditions: p-cloro-metacresol (P-CHLORO-M-CRESOL)

  RDC 528/2021, Anexo (allowed preservatives), entry 22, page 4. Limit: 0.2%.

  Conditions, source text, in Portuguese

  LIMITAÇÕES: Proibido em produtos destinados a entrar em contato com as mucosas.