Compoatlas

QUININE

Official label name (INCI name, EU glossary of cosmetic ingredient names), No 23945

QUININE: Allowed with restrictions, with limits depending on the product type (Annex III, entry 21), under Regulation (EC) No 1223/2009.

In plain words

What it is used for

Functions declared by manufacturers:

Denaturant: renders cosmetics unpalatable. Mostly added to cosmetics containing ethyl alcohol.

Hair conditioning: leaves the hair easy to comb, supple, soft and shiny and/or imparts volume, lightness, gloss, etc.

Fragrance.

What the rules say

Allowed, with restrictions: Annex III sets a maximum concentration and the product types allowed. Ingredient lists do not give quantities, so the concentration cannot be checked on the label.

The text of the annexes

Allowed with restrictions

Entry
Annex III, No 21
Substance
Cinchonan-9-ol, 6'-methoxy-, (8.alpha.,9R)- its salts
Glossary names
QUININE
CAS
130-95-0
EC
205-003-2
Product type
(a) Hair rinse-off products (b) Hair leave-on products
Maximum concentration
(a) 0.5% (as quinine base) (b) 0.2% (as quinine base)
Dates in the act (10)
  • Entry into force on 11 January 2010
  • Application from 1 December 2010
    It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
  • Entry into force on 1 December 2010
  • Condition applicable from 11 January 2012
    As from 11 January 2012, by way of derogation from Directive 76/768/EEC, notification carried out in accordance with Article 13 of this Regulation shall be considered to comply with Article 7(3) and Article 7a(4) of that Directive
  • Application from 11 January 2013
    July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
  • Entry into force on 11 January 2013
  • Application from 11 July 2013
    It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall appl
  • Entry into force on 11 July 2013
  • Placing on the market before 11 July 2013
    Article 39 Transitional provisions By way of derogation from Directive 76/768/EEC, cosmetic products which comply with this Regulation may be placed on the market before 11 July 2013.
  • Placing on the market from 11 July 2013
    As from 11 July 2013, a distributor who makes available in a Member State a cosmetic product already placed on the market in another Member State and translates, on his own initiative, any element of the labelling of that product in order to comply with national law, shall submit, by electronic means, the following info

Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.

Identity

CosIng identifier
37459
CAS (according to CosIng)
130-95-0
EC (according to CosIng)
205-003-2
Declared functions
Denaturant, Hair conditioning, Fragrance
Wikidata
Q189522
PubChem
3034034
ECHA InfoCard
100.004.550
InChIKey
LOUPRKONTZGTKE-WZBLMQSHSA-N

Elsewhere in the world

Information on other jurisdictions. What is covered, and what is not yet.

United Kingdom (Great Britain)

  • Allowed with restrictions (Annex III)

Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

South Korea

  • Restricted: 퀴닌 및 그 염류 (QUININE)

    별표 2, 기타 (other substances with limits), entry 68, page 42. Limit: ․샴푸에 퀴닌염으로서 0.5% ․헤어로션에 퀴닌염로서 0.2%. Conditions (source text, in Korean): 비고: 기타 제품에는 사용금지 | 화학물질명: 퀴닌 (CAS No. 130-95-0)

Australia

  • Subject to conditions (threshold, labelling or packaging): QUININE

    Poisons Standard, Schedule 6 (cosmetic entries), page 279. Thresholds cited: 0.5% or less | 0.2% or less. Conditions (source text): in cosmetic preparations except: | (a) in rinse-off hair preparations containing 0.5% or less of quinine calculated as free base; or | (b) in leave-on hair preparations containing 0.2% or less of quinine calculated as free base.

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.