Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- NAC gélule, declared in 2026
- NAC Apollo's Hegemony, gélule, declared in 2026
- NAC KDAY, gélule, flavour sans arôme, declared in 2026
- NAC gélule, declared in 2026
- NAC gélule, declared in 2026
- NAC Scitec Nutrition, autre : tablette, declared in 2026
- NAC Vitabright, gélule, declared in 2026
- NAC gélule, declared in 2026
- NAC gélule, declared in 2026
- NAC Nutripure, gélule, declared in 2025
- NAC Santé Sauvage, gélule, declared in 2025
- NAC EXVital, gélule, declared in 2025
- NAC BioTechUSA, autre : tablette, declared in 2025
- NAC Sanutrition, capsule, declared in 2025
- NAC Cuure, gélule, declared in 2025
- NAC Insport Nutrition, poudre, flavour sans arôme, declared in 2025
- NAC NUTRABETTER, gélule, declared in 2025
- NAC HX NUTRITION, autre : capsule, declared in 2025
- NAC gélule, declared in 2024
- NAC HERO TECH NUTRITION, gélule, declared in 2024
- NAC & L-GLUTATHION CARIBIOTY, gélule, declared in 2025
- NAC & L-Glutathion réduit Zenement, gélule, declared in 2024
- NAC (Centenarian road) gélule, declared in 2026
- NAC (N-ACETYL L-CYSTEINE) 300 MG HSN, capsule, declared in 2024
- NAC (N-Acétyl Cystéine) 600mg Now Foods, capsule, declared in 2021
- NAC (N-Acétyl Cystéine), 600mg, 100 capsules Now Foods, capsule, declared in 2021
- NAC + Kinoko Life, gélule, declared in 2023
- NAC + Glutathion Platinum Mannavital, gélule, declared in 2025
- NAC - Acétylcystéine DIETANAT, gélule, declared in 2021
- NAC - N-Acetyl-L-Cysteine gélule, declared in 2025
- NAC - N-Acétyl L-Cystéine Biotary, gélule, declared in 2023
- NAC / N-acéty-l-cystéine Valencie Nutrition, gélule, declared in 2026
- NAC / N-acéty-l-cystéine gélule, declared in 2024
- NAC 250mg Warnke Vitalstoffe, gélule, declared in 2024
- NAC 250mg Warnke Vitalstoffe, gélule, declared in 2023
- NAC 250mg Vitamintrend, gélule, declared in 2022
- NAC 250mg Fairvital, gélule, declared in 2021
- NAC 295mg gélule, declared in 2024
- NAC 300 NATURAMedicatrix, gélule, flavour aucun, declared in 2021
- NAC 300 mg IO GENIX, autre : capsule, declared in 2026
- NAC 300 mg DYNAMIX, autre : capsule, declared in 2026
- NAC 300 mg HX NUTRITION, autre : capsule, declared in 2026
- NAC 450mg gélule, declared in 2024
- NAC 450mg gélule, declared in 2020
- NAC 500+ gélule, declared in 2025
- NAC 550 MG HSN, gélule, declared in 2026
- NAC 599 gélule, declared in 2025
- NAC 599 MG HSN, gélule, declared in 2025
- NAC 600 IO GENIX, autre : capsule, declared in 2026
- NAC 600 vit4ever, capsule, declared in 2023
- NAC 600 gélule, declared in 2024
- NAC 600 Raibu natural, gélule, declared in 2023
- NAC 600 IO GENIX, capsule, declared in 2022
- NAC 600 VIT'ALL+, gélule, declared in 2026
- NAC 600 LongLife, gélule, declared in 2025
- NAC 600 LongLife, gélule, declared in 2025
- NAC 600 à libération prolongée gélule, declared in 2025
- NAC 600 N-ACÉTYLCYSTÉINE gélule, declared in 2024
- NAC 600 N-acétyl-cystéine gélule, declared in 2023
- NAC 600mg Orfito bioactive, comprimé, declared in 2019