Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- NAC 700mg Orfito bioactive, comprimé, declared in 2019
- NAC 750 N-ACETYL-L-CYSTEIN Vit4ever, capsule, declared in 2021
- NAC 800 Vit4ever, capsule, declared in 2023
- NAC 90 CAPSULES 600 mg REVTECH, capsule, declared in 2019
- NAC 90 CAPSULES 600 mg HX NATURE, capsule, declared in 2019
- NAC Detox with Milk Thistle Swanson, capsule, declared in 2023
- NAC N acétyl L cystéine DJFORM, gélule, declared in 2023
- NAC N-ACÉTYL CYSTÉINE Dieti Natura, gélule, declared in 2022
- NAC N-ACÉTYL CYSTÉINE Dieti Natura, gélule, declared in 2023
- NAC N-ACÉTYL CYSTÉINE gélule, declared in 2025
- NAC N-ACÉTYL-CYSTÉINE Vita Elements Nature's Power, gélule, declared in 2026
- NAC N-Acetyl Cysteine Nature Provides, gélule, flavour non aromatisé, declared in 2025
- NAC N-Acetyl Cystéine, 1000mg Now Foods, capsule, declared in 2021
- NAC N-Acetylcysteine gélule, declared in 2023
- NAC N-Acéty Cysteine RaissaDora, gélule, declared in 2026
- NAC N-Acétyl-l-cystéine Terravita, gélule, declared in 2025
- NAC N-AcétylCystéine gélule, declared in 2026
- NAC N-Acétylcystéine LABORATOIRES FENIOUX, gélule, declared in 2021
- NAC N-acétyl-cystéine gélule, declared in 2023
- NAC N-acétyl-cystéine gélule, declared in 2024
- NAC N-acétyl-l-cystéine Sanuvit, poudre, declared in 2022
- NAC PLUS ULTRA gélule, declared in 2024
- NAC POWDER poudre, declared in 2026
- NAC Plus comprimé, declared in 2020
- NAC TABS APOLLO'S HEGEMONY, comprimé, declared in 2025
- NAC powder Heiltropfen, poudre, declared in 2026
- NAC with Selenium & Molybdenum, 600mg NOW Foods, capsule, declared in 2023
- NAC+ Apollo's Hegemony, gélule, declared in 2026
- NAC+C NR&D, gélule, declared in 2026
- NAC, 1000mg NOW Foods, comprimé, declared in 2023
- NAC300COMPLEX Pharmaciens Preparateurs, sachet, declared in 2026
- NAC300COMPLEX Pharmaciens Preparateurs, sachet, declared in 2024
- NACAL gélule, declared in 2018
- NADH Plus Therapinov, gélule, declared in 2025
- NAMEDSPORT - NUTRIXAM FORZA NAMEDSPORT, sachet, declared in 2021
- NASH comprimé, declared in 2019
- NATURADETOX gélule, declared in 2017
- NATURADETOX gélule, declared in 2017
- NEO KIDS MOCOSYTOS NEO KIDS, flacon, flavour framboise, declared in 2025
- NEO PEQUES MOCOSYTOS NEO, flacon, flavour framboise, declared in 2020
- NERGEMET gélule, declared in 2026
- NERGEMET® gélule, declared in 2022
- NEUROCHOC+ ERGYSPORT, autre : stick poudre et capsule molle, declared in 2023
- NEUROPLASTINE + Lisarce, gélule, declared in 2026
- NEUTRA'RUB comprimé, declared in 2021
- NIGHT CAPSULES MICROVITAL, gélule, declared in 2026
- NO RUB' FLASH autre : monodose, declared in 2025
- NOVOMA - MULTIVITAMINES NOVOMA, gélule, declared in 2022
- NOVOMA - N-ACÉTYL CYSTÉINE NOVOMA, gélule, declared in 2026
- NO’RUB flacon, declared in 2025
- NO’RUB FLASH Eric Favre, autre : unicadose, declared in 2019
- NUCLEOX NHCO NUTRITION, gélule, declared in 2021
- NUTRANAT CARDIOMEGALG NUTRANAT, capsule, declared in 2023
- NUTRANAT DETOPUR NATUROSUD NUTRANAT, gélule, declared in 2023
- NUTRANAT NAC Protect NUTRANAT, gélule, declared in 2023
- NUTRANAT VISIOMEGALG NATUROSUD NUTRANAT, capsule, declared in 2023
- NUTRAVITA - NAC+ NUTRAVITA, gélule, declared in 2026
- NUTRAVITA - NAC+ gélule, declared in 2025
- NUTRAVITA - L-GLUTATHION gélule, declared in 2022
- NUTRAVITA - NAC N-ACETYL-CYSTEINE capsule, declared in 2021