Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- COMPLEXE DE BIOTINE Nutrabetter, gélule, declared in 2024
- COMPLEXE DE BIOTINE NUTRABETTER, gélule, declared in 2025
- COMPLEXE DE GLUTATHION + PRÉCURSEURS gélule, declared in 2026
- COMPLEXE DE GLUTATHION 500 gélule, declared in 2025
- COMPLEXE DETOX - ARTICHAUT GRANIONS, comprimé, declared in 2023
- COMPLEXE HEPATIQUE ORFITO SYNERGIE, comprimé, declared in 2019
- COMPLEXE MITO SUPPORT gélule, declared in 2025
- COMPLEXE MYO gélule, declared in 2025
- COMPLEXE NATUREL DETOX ADVANCED LINEA WD, capsule, declared in 2019
- CONCEPT 2 comprimé, declared in 2022
- CONCEPTIO ENDOLIB GRANIONS, gélule, declared in 2021
- CORE MINERALS comprimé, declared in 2020
- CRÉATINIUM PhysioNat, poudre, flavour pêche, declared in 2026
- CURCUMA + OMEGA 3 autre : capsules et comprimés, declared in 2020
- CURCUMA + OMEGA 3 comprimé, declared in 2017
- CYCLADYS NHCO NUTRITION, comprimé, declared in 2022
- CYCLOFERT HOMME comprimé, declared in 2016
- Capilhair Capilhair, capsule, declared in 2016
- Carences Suplemint, autre : gélule et comprimé, declared in 2023
- Cellavital L2 Module 4 Fairvital, gélule, declared in 2022
- Cellergize Morning Cellergize, poudre, flavour citron et gingembre, declared in 2026
- Cellular Balance BIFORM, gélule, declared in 2026
- Chardon-Marie, pissenlit, artichaut, N-acétylcystéine (NAC) Bright Naturo, sachet, declared in 2026
- Cheveux et ongles Nutrisvelt, gélule, declared in 2021
- Chrono Inflalyse Laboratoire Activa, gélule, declared in 2025
- Clean Perfect gélule, declared in 2017
- Clear comprimé, declared in 2026
- Clear Skin Formula SuperSmart, gélule, declared in 2025
- Collagène anti-tâche Revitae, poudre, flavour sans arôme, declared in 2024
- Commando 2000 60 comprimés NaturesPlus, comprimé, declared in 2025
- Commando 2000 60 comprimés NaturesPlus, comprimé, declared in 2024
- Complexe Detox H Affynutris, gélule, declared in 2024
- Complexe Détox Équilibre Premium gélule, declared in 2021
- Complexe Gorge Nat&Form, gélule, declared in 2025
- Complexe Nez Nat&Form, gélule, declared in 2025
- Complexe Rub-08 NUTRI S-PRESCRIPTION PARIS, sachet, flavour orange, declared in 2018
- Complexe antioxydant gélule, declared in 2026
- Complexe antioxydant comprimé, declared in 2025
- Complexe antioxydant comprimé, declared in 2025
- Complexe curcuma + oméga premium gélule, declared in 2022
- Complexe hépatique Terravita, gélule, declared in 2024
- Complexe Équilibre Nutritionnel Premium gélule, declared in 2022
- Complexe équilibre enzymes premium gélule, declared in 2021
- Complexe équilibre hépatique premium gélule, declared in 2022
- Comprimés NEUTRA’RUB JOUR / NUIT comprimé, declared in 2026
- Concept Femme IO comprimé, declared in 2025
- Concept Homme comprimé, declared in 2025
- Conception Suplemint, gélule, declared in 2022
- Conversol® gélule, declared in 2025
- Core Minerals USANA, comprimé, declared in 2017
- Cure de peau nuit BioProphyl GmbH, gélule, declared in 2025
- Cyste Plus capsule, declared in 2023
- Cyste Plus gélule, declared in 2018
- Cystenac 600 Be-Life, gélule, declared in 2017
- DAY CAPSULES MICROVITAL, gélule, declared in 2026
- DENSIPOUSSE gélule, declared in 2021
- DEPHEPAT NUTRYTEC, capsule, declared in 2017
- DETOX gélule, declared in 2026
- DETOX Honeylove company, gélule, declared in 2024
- DETOX gélule, declared in 2024
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