CompoAtlas

Leucine in food supplements

748 supplements declared in France contain Leucine as a substance or active ingredient.

Declarations also use the name: L-leucine. Separate page, as the form (L or D) is not always stated.

Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.

What we know about this ingredient

Uses

  • BIOLOGICAL ACTIVITY: Antiencephalopathic

  • Nutrient

  • Nutrient and dietary supplement, biochemical research

  • Reported uses

  • Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#7497]

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · (1) USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Leucine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 9, 2010: https://www.ars-grin.gov/duke/; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 943; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 752; Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1084.

Licence.

Use classification

  • EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

  • Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

  • Cosmetics -> Skin conditioning; Hair conditioning; Antistatic

PubChem : EPA Safer Choice · 2026-10-29 · https://www.epa.gov/saferchoice/safer-ingredients.

Licence.

PubChem : NORMAN Suspect List Exchange · 2026-10-29 · S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118.

Licence.

A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.

Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).

Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.

Natural occurrence recorded in Wikidata (LOTUS database): 134 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.

Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.

Manufacturing

  • By bromination followed by amination of isocaproic acid; via the acetamidomalonic ester; by isolation from gluten, casein, keratin; from hydantoin.

  • Hydrolysis of protein (edestin, hemoglobin, zein), organic synthesis from the alpah-bromo acid.

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1084; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 752.

Licence.

Appearance

  • White crystals

  • White glistening hexagonal plates from aqueous alcohol

PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 752; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 943.

Licence.

Associated research

ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.

2026-11-01

Other names: L-leucine (English), Leucin (German), Leucina (Spanish), leucina (Italian), Leucina (Portuguese).

Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.

Same substance in cosmetics: LEUCINE.

In plain words

À quoi il sert, selon les fabricants

Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Leucine) : sport (404 produits), croissance et developpement (73 produits), système nerveux (22 produits), concentration (17 produits), immunité (14 produits).

Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.

Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.

What the registers say, country by country

Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.

Compl'Alim ingredient list (France): listed.

Compl'Alim, reference list of ingredients, retrieved 21 October 2026.

United States, supplement labels (DSLD; supplements need no prior approval): 572 products.

Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.

Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.

Malaysia, registered products: 1 product.

NPRA, Malaysian pharmaceutical products register, retrieved 27 October 2026.

Ministère de la santé de Malaisie / NPRA, Pharmaceutical Products, CC BY 4.0

CC BY 4.0

Declared daily quantities

Declared daily quantities: Leucine
UnitProductsMedianMinimumMaximum
mg1461,0000126,000

Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.

Products