Compoatlas

DIMETHYLTOLYLAMINE (N,N,4-trimethylbenzenamine)

Official label name (INCI name, EU glossary of cosmetic ingredient names), No 9048

DIMETHYLTOLYLAMINE (N,N,4-trimethylbenzenamine): Prohibited in cosmetics (Annex II, entry 1745), under Regulation (EC) No 1223/2009. Annexes of the Regulation consulted on 21 October 2026.

Who it concerns

This ingredient is prohibited in cosmetics in the European Union: what follows describes its hazards, not a permitted use.

What official classifications and rules say for each group. A classification describes the hazard of the pure substance, not the risk of a product that contains it, which depends on the dose and the exposure.

  • Pregnancy and breastfeeding

    No official classification covers reproduction, the unborn child's development or breastfeeding for this substance.

  • Babies and children

    The Cosmetics Regulation sets no age-related condition for this ingredient.

  • Skin, eyes and allergies

    No official classification for sensitisation, irritation or eye damage, and no obligation to label it as an allergen.

  • Environment

    Classified under the CLP Regulation: hazardous to the aquatic environment, long term, category 3 (Aquatic Chronic 3).

In plain words

What it is used for

Functions declared by manufacturers:

Nail sculpting.

What the rules say

It is prohibited to use it in a cosmetic product sold in the European Union, whatever the dose. If it appears on the ingredient list of a recent product, this needs checking: the record may be old or wrong, or the product intended for another market.

Hazard and risk

The CLP Regulation classifies this substance as carcinogenic, category 1B (presumed effect, established mainly from animal studies).

This classification describes what the substance can cause (a hazard), not what happens when using a product (a risk): the risk depends on the dose, the form and the route of exposure (skin, inhalation, ingestion).

Already prohibited in cosmetics (Annex II).

The text of the annexes

Prohibited in cosmetics

CosIng links the name DIMETHYLTOLYLAMINE to this Annex II entry.

Entry
Annex II, No 1745
Substance
N,N-dimethyl-p-toluidine
CAS
99-97-8
EC
202-805-4
Dates in the act (3)
  • Entry into force on 2 June 2025
  • Application from 1 September 2025
    It shall apply from 1 September 2025.
  • Entry into force on 1 September 2025

Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.

Identity

CosIng identifier
55929
CAS (according to CosIng)
99-97-8
EC (according to CosIng)
202-805-4
Declared functions
Nail sculpting
Wikidata
Q2051705
PubChem
7471
ECHA InfoCard
100.002.551
InChIKey
GYVGXEWAOAAJEU-UHFFFAOYSA-N

Classified hazard (CLP Regulation)

The harmonised classification is the one set by the European Union for the whole Union. H codes refer to the hazard statements of Annex III of Regulation (EC) No 1272/2008.

N,N-dimethyl-p-toluidine

Carcinogenicity, category 1B (Carc. 1B)

Hazard classes
Carcinogenicity, category 1B (Carc. 1B)
Acute toxicity, category 4 (Acute Tox. 4)
Acute toxicity, category 3 (Acute Tox. 3)
Specific target organ toxicity, repeated exposure, category 2 (STOT RE 2)
Hazardous to the aquatic environment, long term, category 3 (Aquatic Chronic 3)
Hazard statements
H350 H332 H301 H373 (blood system, respiratory tract) H412

Elsewhere in the world

Information on other jurisdictions, with no effect on sale in France. What is covered, and what is not yet.

United Kingdom (Great Britain)

  • Prohibited in cosmetics (Annex II)

Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

Brazil

  • Prohibited: N,N-dimetil-p-toluidina

    RDC 529/2021, Anexo (prohibited substances): alterações by RDC 1.030/2026, Art. 3º, entry 1419, page 5.

    Conditions, source text, in Portuguese

    Nº UE: 1745

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.