Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- Oxybiane Homocystéine Regul gélule, declared in 2026
- Oxyperm comprimé, declared in 2019
- PART II FOR MUMMY gélule, declared in 2022
- PBS-dolorix NATURAMedicatrix, gélule, flavour aucun, declared in 2019
- PE autre : 3 composantes : sachets + 2 gélules de formules différentes, declared in 2018
- PEAU-PARFAITE D-LAB NUTRICOSMETICS, gélule, declared in 2019
- PERFECTIUM NHCO Nutrition, gélule, declared in 2019
- PERMEA REGUL FORT sachet, declared in 2022
- PHLEBOXAN 70 GEL NHCO Nutrition, gélule, declared in 2025
- PHYSIONORM ACD sachet, declared in 2022
- PIÙLIFE - GLUTATIONE comprimé, declared in 2025
- PIÙLIFE - NAC comprimé, declared in 2025
- PM Essentials bâton / batônnet / stick, declared in 2019
- POUDRE DE NAC N-ACÉTYLCYSTÉINE poudre, declared in 2024
- PQQ CoQ10 plus NAC et L-Glutathion réduit SOLARAY, gélule, declared in 2023
- PROAGE DAY FORMULA Luxmetique, flacon, declared in 2024
- PROBIOTIC COMPLEX LAZARRAGA, gélule, declared in 2022
- PROCREANAT BIONOPS, gélule, flavour /, declared in 2017
- PROCRELIA Homme Maroc Nurilia, comprimé, declared in 2022
- PROJET BEBE gélule, declared in 2023
- PROJET BÉBÉ ♀ Feel Pure, poudre, declared in 2026
- PROJET BÉBÉ ♂ Feel Pure, gélule, declared in 2026
- PROMELO sirop balsamique DRASANVI, sirop, declared in 2016
- PROSTA CELL NUIT CELLULA PHARM, gélule, flavour neant, declared in 2026
- PROTEXIL comprimé, declared in 2026
- PURE PROFESSIONAL - VITAMIN STRONG PROFESSIONAL comprimé, declared in 2024
- Peau-Parfaite D-LAB NUTRICOSMETICS, gélule, declared in 2024
- Permea poudre, declared in 2026
- Permeabilidad Nenufar sachet, declared in 2023
- Perméa + autre : sachet + gélules, declared in 2024
- Perméa + sans microbiote autre : sachet + gélule, declared in 2024
- Perméa Gold sachet, declared in 2023
- PerméaWaybio Waybio, sachet, declared in 2024
- PerméaWaybio sachet, declared in 2025
- Perméalistique Fort sachet, declared in 2024
- Perméalistique Fort sachet, declared in 2024
- Perturbateurs endocriniens autre : 3 composantes : sachets + 2 gélules de formules différentes, declared in 2019
- PhysioCID™ bâton / batônnet / stick, declared in 2024
- Preconception MyOva, comprimé, declared in 2026
- Premium multivitamines capsule, declared in 2021
- Pro Respiration gélule, declared in 2020
- Procrelia homme Nurilia, comprimé, declared in 2022
- Procrelia homme Nurilia, comprimé, declared in 2025
- Programme Action-Capitons D-LAB NUTRICOSMETICS, gélule, declared in 2023
- Projet bébé SOVA, gélule, declared in 2026
- Projet bébé SOVA, gélule, declared in 2025
- Protectum + LORICA, gélule, declared in 2020
- Proxeed Women sachet, declared in 2018
- Pure Defense avec NAC pure encapsulations, gélule, declared in 2021
- Pure detox bien être du foie Nutripure, sachet, flavour pas d'arôme, declared in 2025
- Pure detox bien être du foie gelule Nutripure, gélule, flavour pas d'arôme, declared in 2025
- PureDetox BioEssentials, gélule, declared in 2024
- Quantapulmo phytoquant, gélule, declared in 2021
- Quantum One flacon, declared in 2026
- Quercétine + NAC DG Supplements, gélule, declared in 2023
- RAIBU - NAC 800 RAIBU ORGANIC, gélule, declared in 2023
- RECODE + EQUILIBRSIT, poudre, flavour fleur de sureau, declared in 2026
- REFILLEST NET BEAUTY SRL, comprimé, declared in 2021
- REGLES DOULOUREUSES gélule, declared in 2023
- RENI FREE comprimé, declared in 2019