Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- REPAIR & PROTECT gélule, declared in 2026
- RESCUE capsule, declared in 2024
- RESFRYHELP BEES HOME PROPOLIS, sachet, declared in 2026
- RESPIR PROTECT SOLARAY, capsule, declared in 2018
- RESPIR'AIR Edith'Erapie, gélule, declared in 2025
- RESPIVANCE comprimé, declared in 2026
- RESVERASOD gélule, declared in 2022
- RETINIUM NHCO NUTRITION, autre : comprimés et capsules, declared in 2024
- RHUMINEX MICRONUTRAE, gélule, declared in 2025
- ReAge Liver Love gélule, declared in 2019
- Receptor Support BIOTICS RESEARCH, gélule, declared in 2025
- Redoxa North American Pharmacal, capsule, declared in 2018
- Respire gélule, declared in 2023
- Respire Bestcare, gélule, declared in 2026
- Respire Bestcare, gélule, declared in 2025
- Respire Bestcare, gélule, declared in 2025
- Restore BioEssentials, gélule, declared in 2026
- Restore HUMAN BY NATURE, gélule, declared in 2023
- Restore Gummies BioEssentials, gomme, declared in 2026
- Rinorub Bronches N-acétylcystéine Forté Pharma, flacon, flavour eucalytus, declared in 2024
- Rub Plus 10 NUTRI S-PRESCRIPTION PARIS, comprimé, declared in 2018
- Rubactifs gélule, declared in 2025
- Rubcontrol sachet, declared in 2024
- Rubcontrol sachet, declared in 2019
- Rubcontrol comprimé, declared in 2019
- S+ Fablife, poudre, flavour framboise, declared in 2026
- S-ACÉTYL-GLUTATHION 100 gélule, declared in 2024
- S-ACÉTYL-GLUTATHION 250 gélule, declared in 2025
- S.O.D.-Complex New Roots Herbal, capsule, declared in 2023
- SEASON VITS HSN, capsule, declared in 2023
- SEASON VITS HSN, autre : capsule végétale, declared in 2024
- SEDATUXIL 3C Pharma, flacon, flavour caramel, declared in 2016
- SEDATUXIL 3C Pharma, flacon, flavour cola, declared in 2019
- SEPTIFERRINE + Lisarce, gélule, declared in 2026
- SIGLEN comprimé, declared in 2017
- SILYNAC comprimé, declared in 2021
- SINUXIN sachet, declared in 2023
- SIROP VOIES RESPIRATOIRES COLA sirop, declared in 2020
- SIROP VOIES RESPIRATOIRES MIEL sirop, declared in 2020
- SKINPERIAL gélule, declared in 2025
- SOPKALM Prescription Nature, poudre, flavour vanille, declared in 2025
- SOS Morning autre : comprimé effervescent, declared in 2025
- SRA Antioxydant NaturaMedicatrix, gélule, declared in 2026
- STAY CLEAN iO.GENIX, capsule, declared in 2024
- STICKS 2 Imane Harmonie, poudre, flavour fruits exotiques, declared in 2025
- SUPLEOX gélule, declared in 2021
- SVRG CO Biomeos, gélule, declared in 2024
- SWISS BIOENERGETICS NAC (N-Acétyl-Cystéine) MADE BY: COUNTERCOM, LTD. capsule, declared in 2021
- SYNERBLOOD gélule, declared in 2024
- SanaLiver SanalysLab, capsule, flavour aucun, declared in 2021
- Senior Suplemint, gélule, declared in 2023
- Sinuxin comprimé, declared in 2023
- Sinuxin comprimé, declared in 2024
- Skinnove éclat. comprimé, declared in 2026
- So protect gélule, declared in 2017
- SteroBalance poudre, flavour orange, declared in 2018
- Stop to spots gélule, declared in 2021
- SublimOOr NOORIA, bâton / batônnet / stick, flavour na, declared in 2026
- Super Glut' poudre, declared in 2025
- Super Multi-Enzyme Be-Life, gélule, declared in 2017