Acétylcystéine in food supplements
1,247 supplements declared in France contain Acétylcystéine as a substance or active ingredient.
Other names in the Compl'Alim list: acetylcysteine, N-acétylcystéine, NAC.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
MUCOLYTIC AGENT (ADJUVANT) FOR BRONCHOPULMONARY DISORDERS
Medicine, biochemical research
Mucolytic; corneal vulnerary; antidote to acetaminophen poisoning
Secretolytic agent
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · SRI; Lewis, R.J., Sr (Ed.). Hawley's Condensed Chemical Dictionary. 12th ed. New York, NY: Van Nostrand Rheinhold Co., 1993, p. 12; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2 83.
Use classification
Cosmetics -> Antioxidant
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 3 taxa; examples: Actaea simplex, Cimicifuga simplex, Homo sapiens.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
... Made by acylating L-cysteine hydrochloride hydrate with acetic anhydride in the presence of sodium acetate.
Direct acetylation of naturally occurring L-cysteine
Preparation and use in treatment of respiratory diseases: Martin, Waller, US 3184505 (1965 to Mead Johnson)
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Ullmann's Encyclopedia of Industrial Chemistry. 6th ed.Vol 1: Federal Republic of Germany: Wiley-VCH Verlag GmbH & Co. 2003 to Present, p. V9 626 (2003); SRI; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17.
Appearance
Crystals from water
WHITE, CRYSTALLINE POWDER
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. 13th Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 17; Osol, A. (ed.). Remington's Pharmaceutical Sciences. 16th ed. Easton, Pennsylvania: Mack Publishing Co., 1980., p. 805.
Odour described
SLIGHT ACETIC ODOR
Stability
Stable in ordinary light; stable at temp up to 120 °C; nonhygroscopic (oxidizes in moist air)
Taste described
CHARACTERISTIC SOUR TASTE
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT07155044 : A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
ACTIVE_NOT_RECRUITING · UTUC, UC (Urothelial Cancer) · 2025-09-04 · NAC
- NCT05142735 : Effects of NAC on Symptoms of CHR Patients
RECRUITING · NA · Prodromal Schizophrenia · 2026-03-27 · N-Acetylcysteine; N-Acetylcysteine (synonym declared in the registry)
- NCT04440280 : Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy
RECRUITING · PHASE2 · Fuchs Endothelial Corneal Dystrophy · 2026-09-02 · N-acetyl cysteine (NAC) 10% solution (synonym declared in the registry); N-acetyl cysteine (NAC) 20% solution (synonym declared in the registry)
2026-11-01
Other names: N-acetyl-L-cysteine (English), Acetylcystein (German), acetilcisteína (Spanish), acetilcisteina (Italian), acetilcisteína (Portuguese).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: ACETYL CYSTEINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Acétylcystéine) : antioxydant (192 produits), immunité (168 produits), détoxifiant / draineur (137 produits), voies respiratoires (78 produits), digestion (56 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 714 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 806 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Poland, notified supplements: 11 products.
GIS, products notified in Poland, retrieved 27 October 2026.
Główny Inspektorat Sanitarny (GIS), Rejestr produktów objętych powiadomieniem
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 399 | 250 | 3 | 600 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- YAMAMOTO NUTRITION - BLACK GUARDIAN comprimé, declared in 2025
- Z-MAN 90 capsules XCORE, gélule, declared in 2018
- ZMAN PROZIS, gélule, declared in 2024
- [MY] ESSENTIELS ACTIVATEUR DE MÉTABOLISME poudre, flavour cerise, declared in 2025
- boostez-vous santé vous nature, gélule, declared in 2025
- glutathion gélule, declared in 2021
- glutathion MS Institut, gélule, declared in 2017
- glutathion + Phyto Or, gélule, declared in 2018
- glyNac therapinov, gélule, declared in 2025
- multi vitamines Medenda, gélule, declared in 2022
- n-acétyl cysteine gélule, declared in 2022
- nuPOWER NUTRITING, comprimé, declared in 2026
- nuPOWER Edition limitée NUTRITING, comprimé, declared in 2026
- septiferrine Bivea, gélule, declared in 2020
- zinc ultra Santé Nature et Science, gélule, declared in 2023
- ACOUCALM EARS 360, gélule, withdrawn from the market
- ACTIRUB COMPRIMES SANTE VERTE, comprimé, withdrawn from the market
- ACTIRUB COMPRIMES SANTE VERTE, comprimé, withdrawn from the market
- ACTIRUB SACHET ENFANT Goût Framboise SANTE VERTE, sachet, flavour framboise, withdrawn from the market
- ACTIRUB SACHET ENFANT Goût Pomme SANTE VERTE, sachet, flavour pomme, withdrawn from the market
- ACTIRUB SACHET ENFANT Goût Pomme SANTE VERTE, sachet, flavour pomme, withdrawn from the market
- ACTIRUB SACHETS SANTE VERTE, sachet, flavour citron, orange, withdrawn from the market
- ACTIRUB SACHETS SANTE VERTE, sachet, flavour citron, orange, withdrawn from the market
- ACTIRUB SACHETS SANTE VERTE, sachet, flavour citron, orange, eucalyptus, withdrawn from the market
- ACTIVATEUR D’ENDURANCE gélule, withdrawn from the market
- AGE-REVERSE D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- ALLERUS comprimé, withdrawn from the market
- ALTO'RUB COMPRIMES DIET HORIZON, comprimé, flavour huile essentielle d'eucalyptus, withdrawn from the market
- ALTO'RUB COMPRIMES DIET HORIZON, comprimé, flavour huile essentielle d'eucalyptus, withdrawn from the market
- ALTO'RUB COMPRIMES DIET HORIZON, comprimé, withdrawn from the market
- ALTO'RUB SACHETS DIET HORIZON, sachet, flavour citron, orange, huile essentielle d'eucalyptus, withdrawn from the market
- ALTO'RUB SACHETS DIET HORIZON, sachet, flavour citron, orange, huile essentielle d'eucalyptus, withdrawn from the market
- ANTIOXYPPIN LEPPIN, gélule, withdrawn from the market
- Activ-Hépato Lorica, gélule, withdrawn from the market
- Activateur Peau Divine D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- Activateur de Métabolisme D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- BABY BOOST homme gélule, withdrawn from the market
- BRONCHOPHYT Prescription Nature, gélule, withdrawn from the market
- Balance tes sucres gélule, withdrawn from the market
- Bien Être Inflamactiv Laboratoire Activa, gélule, withdrawn from the market
- CELINE comprimé, withdrawn from the market
- CELLUREL gélule, withdrawn from the market
- CELLUREL gélule, withdrawn from the market
- CMAR60+ Ok la forme, gélule, withdrawn from the market
- COMPLEXE MITO ReCOVery* gélule, withdrawn from the market
- CONCEPT 2 comprimé, withdrawn from the market
- CONCEPTIO ENDOLIB GRANIONS, gélule, withdrawn from the market
- CONCEPTIO ENDOLIB GRANIONS, gélule, withdrawn from the market
- CORE MINERALS comprimé, withdrawn from the market
- Complexe Équilibre Glutathion Premium gélule, withdrawn from the market
- Condensyl - Homme Nurilia, comprimé, withdrawn from the market
- DAYANG RESPI - voies respiratoires supérieures comprimé, withdrawn from the market
- DERMO-ESTHETIQUE D-LAB NUTRICOSMETICS, autre : comprimé - gélule, withdrawn from the market
- DERMOTIAL capsule, withdrawn from the market
- DETOX gélule, withdrawn from the market
- DETOX-HEPATIQUE & N-Acétyl Cystéine BEAVERHILL, gélule, withdrawn from the market
- DIGEST CONFORT HEPATO SANTE VERTE, comprimé, withdrawn from the market
- Detox gélule, withdrawn from the market
- Detox Active Terravita Laboratoire, gélule, withdrawn from the market
- DÉFIRUB 15 COMPRIMÉS D.Plantes, comprimé, flavour huile essentielle d'eucalyptus, withdrawn from the market