Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- SWISSE ULTIBOOST ENERGIE B+ comprimé, declared in 2019
- SWISSE ULTIVITE COMPLEXE MULTIVITAMINÉ HOMME comprimé, declared in 2019
- SWISSE ULTIVITE Complexe multivitaminé Femme comprimé, declared in 2019
- SWISSE ULTIVITE Complexe multivitaminé Femme 50+ comprimé, declared in 2019
- SWISSE ULTIVITE Complexe multivitaminé Homme 50+ comprimé, declared in 2019
- SYMETIX NHCO NUTRITION, autre : gélule sèche et capsule molle, declared in 2024
- SYNAPSYL NHCO NUTRITION, gélule, declared in 2019
- SYNER-B-MAG® SYNPHONAT, gélule, declared in 2026
- SYNERGIE B gélule, declared in 2025
- SYNERGIE B-COMPLEX gélule, declared in 2019
- SYNERGIE MINCEUR DEAR DOCTOR, comprimé, declared in 2019
- SYNERGIUM Q10 PhysioNat, gélule, flavour aucun, declared in 2026
- SYNERLIFT gélule, declared in 2026
- SYNERMEMORY gélule, declared in 2026
- SYNERSLIM gélule, declared in 2020
- SYNERSMILE gélule, declared in 2026
- SYNERTONUS gélule, declared in 2023
- SYNERTROPHIC SYNPHONAT, sachet, declared in 2016
- SYNERTROPHIC® Citron SYNPHONAT, sachet, flavour citron, declared in 2026
- SYNERTROPHIC® Citron Formule renforcée SYNPHONAT, sachet, flavour citron, declared in 2026
- SYNERTROPHIC® Menthe Formule renforcée SYNPHONAT, sachet, flavour citron, declared in 2026
- SYSNAT MULTIVITAMINES ampoule, declared in 2025
- SYSNAT MULTIVITAMINES ampoule, declared in 2024
- SYSNAT MULTIVITAMINES BÉBÉ ampoule, declared in 2025
- SYSNAT MULTIVITAMINES NEURO+ ampoule, declared in 2026
- Safradiol05 NUTRI S-PRESCRIPTION PARIS, gélule, flavour /, declared in 2026
- Safran + Vitamine B1 & B3 GREEN NATURALS, gélule, declared in 2026
- Santé Cellulaire Longevity Complex #1 NovAging, gélule, flavour neutre, declared in 2026
- Sarfa-Nut D.Plantes, gélule, declared in 2019
- Saw Palmeto Extract Bioherba, gélule, declared in 2025
- Sayonara Hangover Rescue comprimé, declared in 2022
- Schwangerschaft Phase 2 Redcare, gélule, declared in 2024
- Schwangerschaft Phase 3 Redcare, gélule, declared in 2024
- Secret d'eclat MS Institut, gélule, declared in 2017
- Sedamin (CH) gélule, declared in 2026
- SeeRuvite flacon, flavour fraise, declared in 2019
- Senior Suplemint, gélule, declared in 2023
- Senior Complex MARNYS, ampoule, declared in 2019
- SeniorVit GreenFood Nutrition, gélule, declared in 2024
- Sensicaps capsule, declared in 2022
- Seredorm 8 gélule, declared in 2020
- Seredorm8 gélule, declared in 2026
- Seren comprimé, declared in 2020
- Sereno Complex Vitaminor, poudre, declared in 2018
- Sero gélule, declared in 2017
- SeroCalm poudre, declared in 2024
- Seroto Forme gélule, declared in 2020
- Sex Bomb For Him Applied Nutrition, gélule, declared in 2026
- Shape me up YFEN, poudre, flavour chocolat, declared in 2024
- She+ Active comprimé, declared in 2020
- She+ Mature & Fit comprimé, declared in 2021
- She+ Post-pregnancy comprimé, declared in 2021
- She+ Pregnancy autre : comprimés + capsules, declared in 2021
- She+ Skin Complex sachet, declared in 2021
- She+ Sport comprimé, declared in 2021
- Shot de Collagène Marin Bulk, flacon, flavour fuits rouges, declared in 2024
- Shots de Collagène — Formule Marine & CoQ10 MoonRose, flacon, flavour orange, declared in 2026
- Shred-X gélule, declared in 2019
- SiS Advanced Multivitamin comprimé, declared in 2025
- Sildorafil Sildorafil, spray, flavour arôme naturel de mûre (blackberry), declared in 2026
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