Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- 22 VITAMINES, MINERAUX ET PLANTES - DEFENSES IMMUNITAIRES GRANIONS, comprimé, withdrawn from the market
- 23 VITAMINES, MINERAUX ET PLANTES - ENERGIE VITALITE GRANIONS, comprimé, withdrawn from the market
- 24 VITAMINES, MINERAUX ET PLANTES - SENIOR GRANIONS, comprimé, withdrawn from the market
- 24 VITAMINES, MINERAUX ET PLANTES - SENIOR GRANIONS, comprimé, withdrawn from the market
- 360º MULTI PM HSN, comprimé, withdrawn from the market
- 5-MM D-LAB Nutricosmetics, gélule, withdrawn from the market
- 9 MOIS gélule, withdrawn from the market
- ACOUREL gélule, withdrawn from the market
- ACTIBIOTA CHOLESTEROL sachet, withdrawn from the market
- ACTIBIOTA Equilibre et Défense ACTIBIOTA, gélule, withdrawn from the market
- ACTIBIOTA Equilibre et Défense ACTIBIOTA, gélule, withdrawn from the market
- ACTIBIOTA Equilibre et défense ACTIBIOTA, bâton / batônnet / stick, withdrawn from the market
- ACTION 360 MINCEUR, comprimé, withdrawn from the market
- ACTIV 4 RENFORT NATURACTIVE, gélule, withdrawn from the market
- ACTIVATEUR D’ENDURANCE gélule, withdrawn from the market
- AGE-REVERSE D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- ALCALINE complex gélule, withdrawn from the market
- ALL IN ONE LIPOSOMAL flacon, withdrawn from the market
- ALL IN ONE ONE A DAY gélule, withdrawn from the market
- AMINCIL DRAINEUR Ventre Plat Laboratoire Lescuyer, flacon, flavour thé pêche, withdrawn from the market
- ANACA3 Vitalité Anaca3, gélule, withdrawn from the market
- ANACAPS ACTIV+ Laboratoires Dermatologiques Ducray, gélule, withdrawn from the market
- ANACAPS REACTIV Laboratoires Dermatologiques DUCRAY, capsule, withdrawn from the market
- ANACAPS REACTIV Laboratoires Dermatologiques DUCRAY, comprimé, withdrawn from the market
- ANTI CHUTE gélule, withdrawn from the market
- ANTI STRESS KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- ANTI STRESS BIORGANIC NUTRITION, comprimé, withdrawn from the market
- ANXIOREGUL 2 gélule, withdrawn from the market
- ARKOROYAL VITADEFENSES Arkopharma, ampoule, withdrawn from the market
- ARTERIA NHCO NUTRITION, autre : gélule sèche + capsule molle, withdrawn from the market
- ARTHRONOVE gélule, withdrawn from the market
- ARTHROSYNOV + gélule, withdrawn from the market
- ARTICULATIONS ET CARTILAGES gélule, withdrawn from the market
- AUDIPTIL Laboratoires Ilapharm, autre : gélule et capsule, withdrawn from the market
- AUDIPTIL LABORATOIRES ILAPHARM, autre : gélules + capsule, withdrawn from the market
- AUDISTIM® RENFORT+ AUDISTIM, comprimé, withdrawn from the market
- AZINC JUNIOR, gummies ARKOPHARMA, gomme à mâcher, flavour framboises et orange, withdrawn from the market
- Acticult nu3, capsule, withdrawn from the market
- Actifolic gélule, withdrawn from the market
- Action mémoire VIT'ALL+, comprimé, withdrawn from the market
- Activateur Peau Divine D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- Activateur de Métabolisme D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- Activateur de Relaxation D-LAB Nutricosmetics, gélule, withdrawn from the market
- Agenda Hair & Nails Vitamins Agenda, comprimé, withdrawn from the market
- Agenda Multi Man Agenda, comprimé, withdrawn from the market
- Alcaline complex Aragan, gélule, withdrawn from the market
- All-in-one Pure encapsulations, gélule, withdrawn from the market
- Alpha Lipid Lifeline poudre, withdrawn from the market
- Alphalarm capsule, withdrawn from the market
- Alphalarm capsule, withdrawn from the market
- Alvityl Maternité Conception - Grossesse Alvityl, capsule, flavour citron, withdrawn from the market
- Alvityl Mémoire & concentration capsule, flavour vanille, withdrawn from the market
- Alvityl Petit Boost flacon, withdrawn from the market
- Alvityl Vitalité Duo comprimé, withdrawn from the market
- Alvityl Vitalité Effervescent Alvityl, autre : comprimé effervescent, withdrawn from the market
- Alvityl Vitalité Gommes gomme, withdrawn from the market
- Alvityl vitalité 10 vitamines gomme, withdrawn from the market
- Anaca 3 vitalité gélule, withdrawn from the market
- Arterochol 28 PharmaScience, comprimé, withdrawn from the market
- Arterochol 28 Jours PharmaScience, comprimé, withdrawn from the market