Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- CENTRUM® JUNIOR autre : comprimé à sucer ou à croquer, withdrawn from the market
- CENTRUM® MEN comprimé, withdrawn from the market
- CENTRUM® MEN comprimé, withdrawn from the market
- CENTRUM® MEN 50+ comprimé, withdrawn from the market
- CENTRUM® SELECT 50+ comprimé, withdrawn from the market
- CENTRUM® WOMEN comprimé, withdrawn from the market
- CENTRUM® WOMEN 50+ comprimé, withdrawn from the market
- CHEVEUX BOMBSHELL BY LUCILE JOSEPH, gélule, withdrawn from the market
- CHEVEUX & ONGLES Nature Attitude, gélule, withdrawn from the market
- CHEVEUX ET ONGLES gélule, withdrawn from the market
- CHEVEUX ET ONGLES gélule, withdrawn from the market
- CHEVEUX ET ONGLES KERZO gélule, withdrawn from the market
- CHEVEUX, PEAU & ONGLES G&G, gélule, withdrawn from the market
- CHOLESTERON SINGULARIS Superior capsule, withdrawn from the market
- CHOLREG INSTITUT NATURA, gélule, withdrawn from the market
- COLLAFORM gélule, withdrawn from the market
- COLLAGEN EXPRESS autre : fiole, withdrawn from the market
- COLLAGEN SUPER BEAUTY - Peach HSN, poudre, flavour pêche, withdrawn from the market
- COLLAGEN SUPER BEAUTY - Red Fruits HSN, poudre, flavour fruits rouges, withdrawn from the market
- COLLAGEN SUPER BEAUTY** HSN, poudre, flavour pêche, withdrawn from the market
- COLLAGEN SUPER BEAUTY** HSN, poudre, flavour fruits rouges, withdrawn from the market
- COLLAGEN SUPERDOSE - HAIR GROWTH GOLD COLLAGEN, flacon, withdrawn from the market
- COLLAGENE + ANTI-AGE SUBLIMLIFT SHOT FRUITS ROUGES GRANIONS, flacon, flavour fruits rouges, withdrawn from the market
- COLLAGENE + ANTI-AGE SUBLIMLIFT SHOT PECHE GRANIONS, flacon, flavour pêche, withdrawn from the market
- COLLAGENE 1692 MG ET ELASTINE BOTICINAL, comprimé, withdrawn from the market
- COLLAGENE MARIN Confort articulaire Tipa Nutrition, poudre, flavour pamplemousse, withdrawn from the market
- COLLAGENE MARIN DE BRETAGNE bâton / batônnet / stick, withdrawn from the market
- COLLAGENE MARIN DE BRETAGNE poudre, withdrawn from the market
- COLLAGENE MARIN DE BRETAGNE Confort articulaire poudre, flavour pamplemousse, withdrawn from the market
- COMPLEXE DE LUMIERE ACTIVE D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- COMPLEXE ENERGIE gélule, withdrawn from the market
- COMPLEXE MAGNESIUM MARIN + VITAMINES B gélule, withdrawn from the market
- COMPLEXE MULTIVITAMINÉ HOMME comprimé, withdrawn from the market
- COMPLEXE PEAU NETTE ORFITO SYNERGIE, comprimé, withdrawn from the market
- COMPLEXE PILL gélule, withdrawn from the market
- COMPLEXE PILL EXIT gélule, withdrawn from the market
- COMPLEXE PRENATAL VIT'ALL +, comprimé, withdrawn from the market
- COMPLEXE SOLAIRE ORFITO BIOACTIVE, comprimé, withdrawn from the market
- COMPLEXE SOMMEIL gélule, withdrawn from the market
- COMPLEXE SOMMEIL gélule, withdrawn from the market
- COMPLEXE TOTAL DJR VIT'ALL +, comprimé, withdrawn from the market
- COMPLEXE VITAMINES B KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- COMPLEXE VITAMINES B BiOrganic Nutrition, comprimé, withdrawn from the market
- COMPLEXE ÉQUILIBRE ACIDO-BASIQUE PREMIUM bâton / batônnet / stick, withdrawn from the market
- CONCEPT 1 comprimé, withdrawn from the market
- CONCEPT 2 comprimé, withdrawn from the market
- CONCEPTIO ALLAITEMENT GRANIONS, gélule, withdrawn from the market
- CONCEPTIO GROSSESSE GRANIONS, autre : capsule molle + gélule, flavour na, withdrawn from the market
- CONCV PLUS FOR WOMEN sachet, withdrawn from the market
- Cap Sommeil Lorica, comprimé, flavour fleur d'oranger, withdrawn from the market
- Cap Sommeil Lorica, comprimé, flavour mandarine, withdrawn from the market
- Cap Sommeil LORICA, gélule, withdrawn from the market
- Cap Sérénité Lorica, comprimé, withdrawn from the market
- Cap Sérénité G+ Lorica, gélule, withdrawn from the market
- Capillaire Fortifiant OENOBIOL, comprimé, withdrawn from the market
- Capillaire revitalisant OENOBIOL, capsule, withdrawn from the market
- Capital Santé - Système Digestif Forté Pharma, poudre, flavour citron-menthe, withdrawn from the market
- Capital Vitamines PURE, gélule, withdrawn from the market
- Centrum Kids MULTIGUMMIES Centrum, gomme à mâcher, flavour fraise, orange, framboise, withdrawn from the market
- Cheveux & Ongles capsule, withdrawn from the market