Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- PROCRELIA Homme Maroc Nurilia, comprimé, declared in 2022
- PROCYAVIT® CELL PROTECT LPEV Laboratoire, gélule, declared in 2024
- PROGRAMME 72H MINCEUR flacon, declared in 2024
- PROGRAMME ACTIVATEUR CELLULAIRE D-LAB Nutricosmetics, gélule, declared in 2026
- PROJECT X NUTRIWEB, poudre, flavour berry blast, declared in 2023
- PROJECT X NUTRIWEB, poudre, flavour cola craze, declared in 2023
- PROKERACYS 4 EN 1 COMPRIMES GRANIONS, comprimé, declared in 2025
- PROKERACYS ANTI CHUTE 3 MOIS GRANIONS, gélule, flavour /, declared in 2026
- PROLIFE PEDIATRICO flacon, declared in 2026
- PROPHYSIL gélule, declared in 2019
- PROSTA CELL JOUR CELLULA PHARM, poudre, flavour fruits rouges, declared in 2026
- PROSTAPHYTOL VIGOR PLUS gélule, declared in 2025
- PROTEC'SUN gélule, declared in 2024
- PROTECTION CELLULAIRE capsule, declared in 2019
- PROTECTODERM Anti-taches LABORATOIRE LESCUYER, gélule, declared in 2026
- PROTIADVANCE Inovance, poudre, flavour cacao, declared in 2026
- PROTIVANCE INOVANCE, poudre, declared in 2016
- PRÉ-ENTRAÎNEMENT poudre, flavour saveur cerise et cola, declared in 2019
- PSICOBIOTIC NALC BI-LEMA, capsule, declared in 2021
- PSICOBIOTIC PLUS FORTE BI-LEMA, capsule, declared in 2021
- PUISSANCE Pré work-out PURE VITAE, ampoule, declared in 2017
- PUMP NUTREND, poudre, flavour tropical, declared in 2023
- PUMP NUTREND, poudre, flavour bubble gum, declared in 2023
- PUMP NUTREND, poudre, flavour rainbow, declared in 2023
- PUMP XPLODE POWDER OLIMP SPORT NUTRITION, poudre, flavour cola, declared in 2019
- PUMP XPLODE POWDER OLIMP SPORT NUTRITION, poudre, flavour fruit punch, declared in 2018
- PUMP XPLODE POWDER OLIMP SPORT NUTRITION, poudre, flavour fruit punch, declared in 2026
- PUMP XPLODE POWDER OLIMP SPORT NUTRITION, poudre, flavour xplosive cola, declared in 2026
- PUMP XPLODE POWDER OLIMP SPORT NUTRITION, poudre, declared in 2026
- PUNCH POWER SHOT PUNCH POWER, flacon, flavour mangue, declared in 2024
- PURABRAIN gélule, declared in 2022
- PURASLEEP gélule, declared in 2022
- PURAZEN gélule, declared in 2022
- PURBIOTIK EQUILIBRE Natural Nutrition, gélule, declared in 2025
- PURBIOTIK EXPRESS Natural Nutrition, gélule, declared in 2025
- PURE B OMNI capsule, declared in 2022
- PURE ENERGIE sachet, declared in 2023
- PURE GLOW gélule, declared in 2018
- PURE GLOW AIME, gélule, declared in 2022
- PURE HYDRO NUTRYTEC, poudre, flavour chocolat au lait, declared in 2016
- PURE HYDRO NUTRYTEC, poudre, flavour fraise et crème, declared in 2016
- PURE MILTIVITAMINE ADULT comprimé, declared in 2023
- PURE MULTIVITAMINE capsule, declared in 2022
- PURE MULTIVITAMINE JUNIOR comprimé, declared in 2023
- PURE MULTIVITAMINE JUNIOR comprimé, declared in 2023
- PURE MULTIVITAMINE SENIOR comprimé, declared in 2023
- PURE PRE PREGNALIA comprimé, declared in 2023
- PURE PREGNALIA comprimé, declared in 2023
- PURE PRETRAIN XL LABS, poudre, flavour cerise, declared in 2020
- PURE PROFESSIONAL - ANABOLIC BULK saveur CHOCOLAT TSUNAMI NUTRITION, poudre, flavour chocolat, declared in 2025
- PURE PROFESSIONAL - ANABOLIC BULK saveur VANILLE TSUNAMI NUTRITION, poudre, flavour vanille, declared in 2025
- PURE PROFESSIONAL - BLP99.9 811 Comprimés TSUNAMI NUTRITION, comprimé, declared in 2025
- PURE PROFESSIONAL - VITAMIN STRONG PROFESSIONAL comprimé, declared in 2024
- PURE RELAX Tryptophane NINETY NINE LAB PARIS, comprimé, declared in 2022
- PURE VERTIGO NUTRYTEC, poudre, flavour baies, declared in 2018
- PURE VERTIGO NUTRYTEC, poudre, flavour cerise, declared in 2018
- PURE VERTIGO NUTRYTEC, poudre, flavour pomme, declared in 2018
- PURE VITAMINES & MINERAUX PURE AM NUTRITION, gélule, declared in 2023
- PURE WHEY NUTRYTEC, poudre, flavour chocolat blanc, caramel et canelle, declared in 2016
- PURE- GLYCOPURE HYDRA poudre, flavour fruit punch, declared in 2024
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