Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- Relaxoton Mannavital, gélule, declared in 2025
- Remontées acides Cell'innov, gélule, declared in 2025
- Renaissance Glow Rose gélule, declared in 2026
- Renew poudre, declared in 2022
- Repair_K MEDIKAREPRO, gélule, declared in 2021
- Repulpant peau Poméol, gélule, declared in 2023
- Repulpe Collagène Anathéa, ampoule, declared in 2020
- Reset gélule, declared in 2026
- Resilience SVA, gélule, declared in 2021
- Resist'o sucre gélule, declared in 2025
- Rest & Reset Clinique La Prairie Holistic Health, gélule, declared in 2025
- Restaxil comprimé, declared on 3 April 2025, declaration 257172
- Restaxil comprimé, declared on 3 April 2025, declaration 258735
- Restaxil Forte comprimé, declared in 2025
- Restore BioEssentials, gélule, declared in 2026
- Restore Gummies BioEssentials, gomme, declared in 2026
- ResveraCel Thorne, capsule, declared in 2023
- Resveratrol + Nicotinamid Vegavero, gélule, declared in 2020
- Revex HC Scitec Nutrition, gélule, declared on 24 April 2025
- Revex HC Scitec Nutrition, gélule, declared on 12 June 2025
- Revive Active poudre, declared in 2025
- Revive Active Tropical poudre, declared in 2025
- Rhodiola Naturell, comprimé, declared in 2022
- Richelet Cheveux, Peau, Ongles Laboratoire Cellulaire Richelet Paris, capsule, declared in 2022
- Richelet Force des cheveux Laboratoire Cellulaire Richelet Paris, capsule, declared in 2022
- Richelet Hydratation de la peau Laboratoire Cellulaire Richelet Paris, capsule, declared in 2022
- Richelet Régénération de la Peau Stick Laboratoire Cellulaire Richelet Paris, bâton / batônnet / stick, declared in 2024
- Richelet Régénération de la peau Laboratoire Cellulaire Richelet Paris, comprimé, declared in 2022
- Rituel Pureté Lumière Moslate, ampoule, declared in 2026
- Rituel Pureté Lumière JSAWELL, ampoule, declared in 2026
- Rosa Spirit B!TONIC, capsule, declared in 2017
- Routine Cheveux Bouclés Laboratoire Forté Pharma, gélule, declared in 2026
- Routine Cheveux Frisés Laboratoire FORTE PHARMA, gélule, declared in 2026
- Routine Cheveux Raides Forté Pharma, gélule, declared in 2026
- Royal Restore RLK6, gélule, declared in 2016
- Rush RTD Berry autre :, flavour baies rouges, declared in 2024
- Rush RTD Orange autre :, flavour orange, declared in 2024
- RÉSILIENCE CAPILLAIRE Jamali, gélule, declared in 2025
- Règles douloureuses Laboratoire Rebaud & Rolhion, spray, flavour cassis, declared in 2025
- Récupération OPHYCURE, gélule, declared in 2022
- Régul'pellicule gélule, declared in 2025
- Régul'sébum gélule, declared in 2025
- Régénum gélule Lorica, gélule, declared in 2026
- Régénum pot Lorica, poudre, flavour pêche, declared in 2026
- Réparation et nutrition extrême gélule, declared in 2020
- S'SENSE MINCEUR S'SENSE VEGETAL, comprimé, declared in 2020
- S'SENSE VITALE S'SENSE VEGETAL, comprimé, declared in 2020
- S.O.D. d'Okinawa gélule, declared in 2017
- S.O.D. d'Okinawa gélule, declared in 2024
- S2S gélule, declared in 2025
- S4+ bâton / batônnet / stick, declared in 2023
- SAFRA NUT D.Plantes, gélule, declared in 2021
- SAFRANIA 5-HTP ÉQUILIBRE PREMIUM gélule, declared in 2025
- SAFRANIA 5HTP comprimé, declared in 2019
- SAFROCALM SORIAVIE, gélule, declared in 2024
- SAFROSAN comprimé, declared in 2018
- SALT CAPS capsule, declared in 2018
- SALT CAPS NUTREND, gélule, declared in 2019
- SAMATA sachet, declared in 2020
- SANAFLORE poudre, declared in 2024
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