Compoatlas

HEXETIDINE

Official label name (INCI name, EU glossary of cosmetic ingredient names), No 11952

HEXETIDINE: Preservative allowed under conditions, maximum 0.1% in the ready-for-use preparation (Annex V, entry 19), under Regulation (EC) No 1223/2009.

In plain words

What it is used for

Functions declared by manufacturers:

Antimicrobial: helps control the growth of micro-organisms on the skin.

Oral care: provides cosmetic effects to the oral cavity, e.g. cleansing, deodorising, protecting.

Preservative: inhibits primarily the development of micro-organisms in cosmetics.

What the rules say

An ingredient can be used as a preservative only if it appears on the list of Annex V. <function plain_language.<locals>.name at 0x7f7805a944a0> is on it with a maximum concentration.

The text of the annexes

Preservative allowed under conditions

Entry
Annex V, No 19
Substance
5-Pyrimidinamine, 1,3-bis(2-ethylhexyl)hexahydro-5-methyl-
Glossary names
Hexetidine
CAS
141-94-6
EC
205-513-5
Maximum concentration
0.1%
Dates in the act (10)
  • Entry into force on 11 January 2010
  • Application from 1 December 2010
    It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
  • Entry into force on 1 December 2010
  • Condition applicable from 11 January 2012
    As from 11 January 2012, by way of derogation from Directive 76/768/EEC, notification carried out in accordance with Article 13 of this Regulation shall be considered to comply with Article 7(3) and Article 7a(4) of that Directive
  • Application from 11 January 2013
    July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall apply from 11 January 2013.
  • Entry into force on 11 January 2013
  • Application from 11 July 2013
    It shall apply from 11 July 2013, with the exception of: — Article 15(1) and (2) which shall apply from 1 December 2010, as well as Articles 14, 31 and 32 to the extent that they are necessary to apply Article 15(1) and (2); and — Article 16(3) second subparagraph, which shall appl
  • Entry into force on 11 July 2013
  • Placing on the market before 11 July 2013
    Article 39 Transitional provisions By way of derogation from Directive 76/768/EEC, cosmetic products which comply with this Regulation may be placed on the market before 11 July 2013.
  • Placing on the market from 11 July 2013
    As from 11 July 2013, a distributor who makes available in a Member State a cosmetic product already placed on the market in another Member State and translates, on his own initiative, any element of the labelling of that product in order to comply with national law, shall submit, by electronic means, the following info

Excerpts from the English text published in the Official Journal. A date may concern only some substances of the act: the excerpt says so.

Identity

CosIng identifier
34266
CAS (according to CosIng)
141-94-6
EC (according to CosIng)
205-513-5
Declared functions
Antimicrobial, Oral care, Preservative
Wikidata
Q419749
PubChem
3607
ECHA InfoCard
100.005.012
InChIKey
DTOUUUZOYKYHEP-UHFFFAOYSA-N

Elsewhere in the world

Information on other jurisdictions. What is covered, and what is not yet.

United Kingdom (Great Britain)

  • Preservative allowed under conditions (Annex V)

Same entries as in the European Union. Conditions (concentrations, warnings) may differ: they are not compared here.

Switzerland

Regulation (EC) No 1223/2009 applies in Switzerland (Article 54 of the Ordinance on Foodstuffs and Utility Articles).

United States, federal rules

None of the integrated sections of the federal code (21 CFR 700.11 to 700.27 and 250.250) targets this name. The FDA does not publish a list of allowed ingredients.

South Korea

  • Restricted: 헥세티딘 (HEXETIDINE)

    별표 2, 보존제 성분 (preservatives), entry 58, page 13. Limit: 사용 후 씻어내는 제품에 0.1%. Conditions (source text, in Korean): 비고: 기타 제품에는 사용금지

Brazil

  • Allowed under conditions: Amino-5-bis(etil-2-hexil)-1,3 metil-5-perhidropirimidina (HEXETIDINE)

    RDC 528/2021, Anexo (allowed preservatives), entry 18, page 3. Limit: 0,1%.

Glossary: Commission Implementing Decision (EU) 2025/1175. Page updated on 21 October 2026.