Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- EVOFUEL - BLACKCURRANT HSN, poudre, flavour blackcurrant, withdrawn from the market
- EVOFUEL - BLUE RASPBERRY HSN, poudre, flavour blue raspberry, withdrawn from the market
- FLEX PROTECT Laboratoires SYNActifs, gélule, withdrawn from the market
- HAIR BASE Aderans hair care, gélule, withdrawn from the market
- HAIR BOOSTER PLUS ELLIKRIL, gélule, withdrawn from the market
- HAIR FORCE Aderans HAIR CARE, gélule, withdrawn from the market
- HAIR GLOW MAMA CHILL, gélule, withdrawn from the market
- HERPESYL gélule, withdrawn from the market
- HYDRO-S Peau Serie Radieuse, compte-gouttes, withdrawn from the market
- Hot Blood Hardcore No-Stim poudre, flavour orange, withdrawn from the market
- Hot Blood Hardcore No-Stim poudre, flavour tropical punch, withdrawn from the market
- IMMUN'IN + LABORATOIRE physiosens, gélule, withdrawn from the market
- IMMUN'IN + Laboratoire Physiosens, gélule, withdrawn from the market
- IRON PERFORMANCE ERIC FAVE SPORT, gélule, withdrawn from the market
- IRON PERFORMANCE ERIC FAVE SPORT, gélule, withdrawn from the market
- IRON ULTRA FAT BURNER ERIC FAVRE SPORT, gélule, withdrawn from the market
- Iron ultra fat burner gélule, withdrawn from the market
- KERATINE PRO PLUS MEDIPRIX, gélule, withdrawn from the market
- L-Lysine Kruidvat, comprimé, withdrawn from the market
- LYSINE Vimergy, capsule, withdrawn from the market
- Mineral Vit Magnum Be-Life, gélule, withdrawn from the market
- Mix CPL Alimed, poudre, flavour sans ajout, withdrawn from the market
- NutriProtect Detox poudre, withdrawn from the market
- OstéoRenov Lorica, sachet, withdrawn from the market
- OstéoRénov Lorica, poudre, flavour fruits exotiques, withdrawn from the market
- OstéoRénov Lorica, poudre, flavour fruits exotiques, withdrawn from the market
- OstéoRénov Lorica, sachet, withdrawn from the market
- OstéoRénov Lorica, poudre, withdrawn from the market
- Physiocap Laboratoires Yves Ponroy, gélule, withdrawn from the market
- Pianto Agrumes Pianto, flacon, withdrawn from the market
- REGENER 8 gélule, withdrawn from the market
- Regenum Lorica, poudre, flavour agrumes, withdrawn from the market
- Regenum Forte Lorica, bâton / batônnet / stick, flavour agrumes, withdrawn from the market
- Regenum Forte Lorica, bâton / batônnet / stick, flavour agrumes, withdrawn from the market
- Regenum Forte Lorica, sachet, flavour agrumes, withdrawn from the market
- Regenum Forte Lorica, sachet, withdrawn from the market
- Regenum Forte Lorica, sachet, withdrawn from the market
- Régénum pot Lorica, poudre, flavour pêche, withdrawn from the market
- Régénum pot Lorica, poudre, flavour pêche, withdrawn from the market
- SILENCE ÇA POUSSE ITSMY, gélule, withdrawn from the market
- Syléance Ménocontrol 45+ Yves Ponroy, gélule, withdrawn from the market
- T-REX - PRE WORKOUT ENERGY T-REX INTEGRATORI, poudre, flavour orange et pêche, withdrawn from the market
- Tendoactive Plus Forté Pharma Médical, bâton / batônnet / stick, flavour orange/citron, withdrawn from the market
- Ultra Sport Vitamines flacon, withdrawn from the market
- VECTIREGYL NUTERGIA, gélule, withdrawn from the market
- VITAMINO+ ERIC FAVRE SANTE, comprimé, withdrawn from the market
- Vegan Collagene Booster Iswari, poudre, withdrawn from the market
- Vitacor Plus Drink Dr. Rath, poudre, withdrawn from the market
- Zero EAA PROZIS, poudre, flavour citron-citron vert, withdrawn from the market
- Zero EAA PROZIS, poudre, flavour mangue-pêche, withdrawn from the market
- ÉQUILIBRE COLLAGÈNE MARIN 10GR PREMIUM poudre, withdrawn from the market