Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- 3A-AJR Titis, capsule, declared in 2018
- 9 AA Biote poudre, declared in 2019
- ACIDES AMINES DU COLLAGENE 4.4.1 NUTRIMUSCLE, poudre, flavour naturel, declared in 2024
- ACIDES AMINES DU COLLAGENE 4.4.1 NUTRIMUSCLE, gélule, flavour naturel, declared in 2024
- ACIDES AMINES GELULE G&G, gélule, declared in 2020
- ACIDES AMINES POUDRE G&G, poudre, declared in 2020
- ACIDES AMINÉS ESSENTIELS 150 COMPRIMÉS 1600 mg HX NATURE, comprimé, declared in 2019
- AFTER CROSS IO GENIX, poudre, flavour green apple, declared in 2021
- AMINO 6000 Galvanize Nutrition, comprimé, declared in 2018
- AMINO 99 BEST PROTEIN, comprimé, declared in 2019
- AMINO ACID COMPLEX comprimé, declared in 2024
- AMINO EDGE AMINOSMART, poudre, flavour pomme, declared in 2018
- AMINO FUEL poudre, flavour framboise bleu, declared in 2019
- AMINO NIGHT NUTRYTEC, poudre, flavour framboise, declared in 2016
- AMINO NIGHT NUTRYTEC, poudre, flavour citron, declared in 2016
- AMINOPEP BEST PROTEIN, comprimé, declared in 2019
- AMIX™ M.A.P.® - 300 g poudre, declared in 2025
- AMIX™ M.A.P.® - 340 g poudre, declared in 2025
- AMIX™ M.A.P® comprimé, declared in 2025
- AMIX™ M.A.P® 375 TBL comprimé, declared in 2025
- AMIX™ YEEP NO CAFF PUMP™ (Jungle monster) Amix™, poudre, flavour jungle monster, declared in 2025
- AMIX™ YEEP NO CAFF PUMP™ (Pear strike) Amix™, poudre, flavour pear strike, declared in 2025
- ANABOLIC AMINOS HX NUTRITION, comprimé, declared in 2022
- ANCIENT + BRAVE - RADIANT COLLAGYN poudre, declared in 2024
- ANDROHAIR CAXEMIR, gélule, declared in 2022
- ANDROKARE NATURELLE, gélule, declared in 2024
- ANMAX PHYTEXTRA, gélule, declared in 2021
- ANTI-CHUTE HARMONY CURE, gélule, declared in 2024
- ARGELINE LABORATOIRE BIOCRYSTAL, poudre, declared in 2018
- ARGININE-ORNITHINE-LISINE 90 CAPSULES 1020 MG HX NUTRITION, capsule, declared in 2018
- Acide hyaluronique Théralica, gélule, flavour aucun, declared in 2025
- Ambrosial Men's Multivitamin 120 Tablets comprimé, declared in 2026
- Amino Charge Scitec Nutrition, poudre, flavour cola, declared in 2021
- Amino Charge Scitec Nutrition, poudre, flavour bubble gum, declared in 2021
- Amino Charge Scitec Nutrition, poudre, flavour bleue framboise, declared in 2021
- Amino Charge Scitec Nutrition, poudre, flavour pomme, declared in 2021
- Amino Charge Scitec Nutrition, poudre, flavour abricot, declared in 2021
- Amino Complete NOW Foods, gélule, declared in 2026
- Amino Complex Vitality Nutritionals, gélule, declared in 2021
- Amino Complex Bioherba, gélule, declared in 2024
- Amino Energy Optimum Nutrition, poudre, flavour pêche - canneberge, declared in 2016
- Amino Energy Optimum Nutrition, poudre, flavour pastèque, declared in 2016
- Amino Energy Optimum Nutrition, poudre, flavour citron vert - menthe, declared in 2016
- Amino Energy - Cherry Optimum Nutrition, poudre, flavour cerise, declared in 2017
- Amino Energy - Cola Optimum Nutrition, poudre, flavour cola, declared in 2017
- Amino Energy - THÉ GLACÉ Optimum Nutrition, poudre, flavour thé glacé, declared in 2017
- Amino Fuel Applied Nutrition, poudre, flavour icy blue raz, declared in 2026
- Amino Fuel Applied Nutrition, poudre, flavour fruit burst, declared in 2026
- Amino Fuel (EAA) Applied Nutrition, poudre, flavour fruit salad, declared in 2022
- Amino Fuel (EAA) Applied Nutrition, poudre, flavour fruit burst, declared in 2022
- Amino Liquid Scitec Nutrition, autre :, flavour cherry-guava, declared in 2023
- Amino PRO MP9 bâton / batônnet / stick, declared in 2020
- Amino Prime Prozis, poudre, flavour ananas, declared in 2020
- Amino Prime Prozis, poudre, flavour cola, declared in 2020
- Amino Prime Prozis, poudre, flavour pomme verte, declared in 2020
- Amino Prime Prozis, poudre, flavour limonade rose, declared in 2020
- Amino Prime Prozis, poudre, flavour neutre, declared in 2020
- Amino Prime Caffeine Free Prozis, poudre, flavour pomme verte, declared in 2020
- Amino Prime Caffeine Free Prozis, poudre, flavour limonade rose, declared in 2020
- Amino Prime Caffeine Free Prozis, poudre, flavour ananas, declared in 2020
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- Pro-Equalizer Protein Powder Supplement from the US market
- Nutritional Management Pack Supplement from the US market
- Pro-Equalizer Protein Powder Supplement from the US market
- Ultra Protein Plus Natural Chocolate Almond Flavor Supplement from the US market
- Pro-Shake 19 Natural Vanilla Protein Powder Supplement from the US market
- Ultra Protein Plus Natural Vanilla Bean Flavor Supplement from the US market
- Aminoplus Supplement from the US market
- Metabolic Cleanse Supplement from the US market
- Sports Performance Pro-PCA Fuel Training Session Formula Supplement from the US market
- Sports Performance Pro-PCA Fuel Natural Raspberry Flavor Supplement from the US market
- Ultra Protein Plus Natural Vanilla Bean Flavor Supplement from the US market
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- Pork Gelatin Unflavored Supplement from the US market
- Collagen Bone Hydrolysate Unflavored Supplement from the US market
- Collagen Hydrolysate Apple + Cucumber Flavored Supplement from the US market
- Alive! Ultra Shake Vanilla Flavored Supplement from the US market
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- Alive! Multi-Vitamin Supplement from the US market
- Glycoplex Supplement from the US market
- Gynecrine Supplement from the US market
- Multi Caps Supplement from the US market
- Lysinol Supplement from the US market
- Intra-Aid Blue Raspberry Supplement from the US market
- Intra-Aid Citrus Burst Supplement from the US market
- Amino 2700 Supplement from the US market
- Universal Amino 2700 Supplement from the US market
- Amino 2700 Supplement from the US market
- Amino 2250 Supplement from the US market
- Amino 2250 Supplement from the US market
- Amino 2250 Supplement from the US market
- Animal Pak Supplement from the US market
- Animal Pak Supplement from the US market
- Animal Pak Supplement from the US market
- Animal Nitro Supplement from the US market
- Animal Nitro Supplement from the US market
- Animal Pak Orange Crushed Flavor Supplement from the US market
- Animal Pak Cherry Bomb Flavor Supplement from the US market
- Fat Burners Supplement from the US market
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- Amino 1000 Supplement from the US market
- Amino 1900 Supplement from the US market
- Amino 1900 Supplement from the US market
- Insane Amino Hellboy Blue Raspberry Supplement from the US market