Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Strawberry Cream ZOOMADLABS, poudre, flavour fraise et crème, declared in 2026
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Tropic Madness ZOOMADLABS, poudre, flavour tropical, declared in 2026
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Twister Berries ZOOMADLABS, poudre, flavour fruits rouges, declared in 2026
- ZOOMADLABS - CARE TAKER GLOW Berry Blast ZOOMADLABS, poudre, flavour fruits rouges, declared in 2026
- ZOOMADLABS - CARE TAKER GLOW Ice Melon ZOOMADLABS, poudre, flavour melon glacé, declared in 2026
- ZOOMADLABS - CARE TAKER GLOW Lime Lemon ZOOMADLABS, poudre, flavour lime-citron, declared in 2026
- ZOOMADLABS - CARE TAKER GLOW Mad Mango ZOOMADLABS, poudre, flavour mangue, declared in 2026
- ZOOMADLABS - CARE TAKER MAP Cherry Bomb ZOOMADLABS, poudre, flavour cerise, declared in 2026
- ZOOMADLABS - CARE TAKER MAP Cool Lemon ZOOMADLABS, poudre, flavour citron, declared in 2026
- ZOOMADLABS - CARE TAKER MAP Silk Orange ZOOMADLABS, poudre, flavour orange, declared in 2026
- Zero EAA PROZIS, poudre, flavour poire, declared in 2019
- Zero EAA PROZIS, poudre, flavour pomme verte, declared in 2019
- Zero EAA PROZIS, poudre, flavour citron-kiwi, declared in 2019
- Zest Active poudre, declared in 2025
- Zest Active Berry poudre, declared in 2025
- acides aminés 19 gélule, declared in 2022
- acides aminés formule gélule, declared in 2019
- formule acides aminés 17 gélule, declared in 2018
- intra-amino adapt, poudre, flavour ananas, declared in 2018
- muscle maker MMUSA, compte-gouttes, flavour framboise, declared in 2025
- nutrabytes - Advanced Marine Collagen flacon, declared in 2025
- nutrabytes - Advanced Vegan Collagen gélule, declared in 2025
- nutri+ EAA 6000 Tabs Nutri-Plus, comprimé, flavour neutre, declared in 2023
- nutri+ EAA Caps Nutri-Plus, capsule, declared in 2023
- nutri+ VHEY® Gainer Banoffee Nutri-Plus, poudre, flavour banoffee, declared in 2023
- nutri+ VHEY® Gainer Chocolate Brownie Nutri-Plus, poudre, flavour brownie au chocolat, declared in 2023
- nutri+ VHEY® Gainer Natural Nutri-Plus, poudre, flavour neutre, declared in 2023
- nutri+ VHEY® Gainer Vanilla Cookie Nutri-Plus, poudre, flavour biscuit à la vanille, declared in 2023
- ongles et cheveux Bite Sens, gomme, flavour franbuesa, declared in 2025
- strong blast n.o Bodybuilding Labs, poudre, flavour citron vert, declared in 2016
- ÉNERGIE capsule, declared in 2022
- Équilibre Collagène 10G poudre, declared in 2023
- Équilibre Collagène 5G sachet, declared in 2023
- A king of magic BIRDIE, gélule, withdrawn from the market
- ARTERIA NHCO NUTRITION, autre : gélule sèche + capsule molle, withdrawn from the market
- Amino Prime Prozis, poudre, flavour citron, withdrawn from the market
- Amino Prime Caffeine Free Prozis, poudre, flavour neutre, withdrawn from the market
- Amino Prime Caffeine Free Prozis, poudre, flavour citron, withdrawn from the market
- Amino Recovery PROZIS, poudre, flavour citron-kiwi, withdrawn from the market
- Amino Recovery PROZIS, poudre, flavour naturel, withdrawn from the market
- Bien Être Inflamactiv Laboratoire Activa, gélule, withdrawn from the market
- Big Shot Pre-Workout PROZIS, poudre, flavour explosion de fruit, withdrawn from the market
- COMPLEXE RECOVERY AMINO+ gélule, withdrawn from the market
- Cheveux & Ongles - Complexe Beauté Vitavea Laboratoires Yves Ponroy, gélule, withdrawn from the market
- Complexe Boosteur de Pousse D-LAB Nutricosmetics, gélule, withdrawn from the market
- Complexe cheveux & ongles orfito synergie, comprimé, withdrawn from the market
- Complexe Équilibre Collagène Marin Premium gélule, withdrawn from the market
- Complexe Équilibre Collagène Marin Premium poudre, withdrawn from the market
- EAA - Acides Aminés Essentiels PROZIS, poudre, flavour pomme verte, withdrawn from the market
- EAA - Acides Aminés Essentiels PROZIS, poudre, flavour citron-citron vert, withdrawn from the market
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour tropical, withdrawn from the market
- EAA - Acides Aminés Essentiels PROZIS, poudre, flavour cola, withdrawn from the market
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour blueberry-melon, withdrawn from the market
- EAA - Acides Aminés Essentiels PROZIS, poudre, flavour mangue-pêche, withdrawn from the market
- EAA - Acides Aminés Essentiels PROZIS, poudre, flavour (sans goût), withdrawn from the market
- EAA - Acides Aminés Essentiels Prozis, poudre, flavour orange, withdrawn from the market
- EAAs Tabs PROZIS, comprimé, withdrawn from the market
- EAAs Tabs Prozis, comprimé, withdrawn from the market
- ERGYSPORT FLEX NUTERGIA, sachet, withdrawn from the market
- ESSENTIAL AMINOACIDS 150 COMPRIMÉS 1600 MG HX NUTRITION, comprimé, withdrawn from the market