Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- STACKER2 EUROPE - ESSENTIAL AMINOS Tropical Fruit STACKER2 EUROPE, poudre, flavour tropical fruit, declared in 2026
- SUPER IMUNIVAIR NOVAPHYT, comprimé, declared in 2020
- SUPRAVITAL nutri&form, gélule, declared in 2017
- She+ Mature & Fit comprimé, declared in 2021
- Skin Glow + poudre, declared in 2026
- Soutien au Collagène Végétalien Nutrality, autre : liquide prêt à boire, flavour baies mélangées, declared in 2023
- Sport + poudre, declared in 2026
- Stim Free Burner Scitec Nutrition, gélule, declared in 2025
- Super Burner BiotechUSA, comprimé, declared in 2025
- Super Fat Burner BiotechUSA, gélule, declared in 2025
- Super Lipo BiotechUSA, comprimé, declared in 2025
- Super Multi-Enzyme Be-Life, gélule, declared in 2017
- Supplément alimentaire avec de la spermidine Vitabay, gélule, declared in 2026
- T-REX - ACIDES AMINÉS ESSENTIELS T-REX INTEGRATORI, poudre, flavour saveur baies, declared in 2022
- T-REX - ACIDES AMINÉS ESSENTIELS T-REX INTEGRATORI, poudre, flavour saveur thé pèche, declared in 2022
- T-REX - ACIDES AMINÉS ESSENTIELS T-REX INTEGRATORI, comprimé, declared in 2022
- T-REX - PRE WORKOUT ENERGY T-REX INTEGRATORI, poudre, flavour pêche, declared in 2023
- THE AMINO 6000 THE nutrition, comprimé, declared in 2016
- TIME Magnesium TIME Nutrition, gélule, declared in 2016
- TIME Tryptophan TIME Nutrition, gélule, declared in 2016
- TOP SKIN ULTIMATE-WELLNESS LINE, poudre, flavour orange, declared in 2018
- TRANSIT Laboratoires Activa, gélule, declared in 2024
- TRICHONUTRI AROMAS COSMETIQUES, gélule, declared in 2024
- TSUNAMI NUTRITION - AMINO ESSENTIAL comprimé, declared in 2024
- TSUNAMI NUTRITION - RECOVERY 2.0 TSUNAMI NUTRITION, poudre, flavour fruits rouges, declared in 2026
- TSUNAMI NUTRITION - RECOVERY 2.0 (RED BLUE PASSION) poudre, flavour red blue passion, declared in 2024
- Tendoactive Plus Forté Pharma Médical, bâton / batônnet / stick, flavour orange/citron, declared in 2020
- Tri-Amino Mix Warnke Vitalstoffe, comprimé, declared in 2021
- Ultidense ULTI Paris, autre : shot buvable en flacon pet, flavour mangue - citron, declared in 2026
- Ultra Burner Conquer Sports, gélule, flavour aucune, declared in 2025
- Ultra Peau Ongles Cheveux NaturesPlus, comprimé, declared in 2025
- Ultra Peau Ongles Cheveux avec MSM comprimé, declared in 2019
- VASCUL'O LABORATOIRE Physiosens, gélule, declared in 2023
- VEGAN COLLAGEN COMPLEX VEGAN VITALITY, gélule, declared in 2021
- VEGAN COLLAGENE Prokopton, poudre, flavour pêche, declared in 2023
- VEGANLIFE AMINO+ gélule, declared in 2026
- VEGANLIFE AMINO+ gélule, declared in 2024
- Vegan Collagen foodspring, poudre, flavour goût citron, declared in 2024
- Vegan Collagen Gummies Novomins, autre : gummies, declared in 2023
- Vegan Collagene Booster Iswari, poudre, declared in 2026
- Vegan Pro-Collagen Igennus Healthcare Nutrition, poudre, declared in 2022
- VitaKAre MediKArePro, gélule, declared in 2020
- Vitastrong EAA PRO TABS comprimé, declared in 2026
- Vollagen + Hyaluronsäure Vegavero, gélule, declared in 2025
- Vollagen + Hyaluronsäure Vegavero, gélule, declared in 2022
- Végétalien Multivitamines Nutrality, autre : liquide prêt à boire, flavour orange, declared in 2023
- WARRIOR CREATINE PLUS EAA poudre, declared in 2025
- WARRIOR ESSENTIAL AMINO ACIDS poudre, declared in 2025
- WeightWorld Bovine Collagen Peptides (90% Protein) 500g Powder poudre, declared in 2020
- Whey Protein ISO Elite Performance Overall Athletica, poudre, flavour chocolat royal, declared in 2026
- XPLENDOR DRASANVI, capsule, declared in 2018
- XPLENDOR DRASANVI, capsule, declared in 2017
- Youhair You beauty, gélule, declared in 2025
- Youth Biotics gélule, declared in 2025
- ZEN FIT goût pastèque bâton / batônnet / stick, flavour pastèque, declared in 2016
- ZEN FIT goût punch aux fruits bâton / batônnet / stick, flavour punch aux fruits, declared in 2016
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Cherry Bomb ZOOMADLABS, poudre, flavour cerise, declared in 2026
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Cool Lemon ZOOMADLABS, poudre, flavour citron, declared in 2026
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Fresh Cola ZOOMADLABS, poudre, flavour cola, declared in 2026
- ZOOMADLABS - CARE TAKER 10:1:1 AKA "GUARDIÁN"– Silk Orange ZOOMADLABS, poudre, flavour orange, declared in 2026