Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- Vitalité Petit Chêne, flacon, withdrawn from the market
- Vitalité Nut Fruits Rouge Direct Plantes, autre : comprimés effervescents, flavour framboise, cassis, withdrawn from the market
- Vitalité Ongles & Cheveux PHYDERMA, comprimé, withdrawn from the market
- Vitalité Ongles et Cheveux comprimé, withdrawn from the market
- Vitalité ongles & cheveux PHYDERMA, comprimé, withdrawn from the market
- Vitalité-Nut Dplantes, autre : comprimé effervescent, flavour citron vert - menthe, withdrawn from the market
- Vitalité-nut D.Plantes, autre : comprimés effervescents, flavour citron vert et menthe, withdrawn from the market
- Vitalité-nut D.Plantes, autre : comprimés effervescents, flavour citron vert et menthe, withdrawn from the market
- VitamAO Boost Compalia, gélule, withdrawn from the market
- Vitamine B COMPLEXE 50 VIT'ALL+, comprimé, withdrawn from the market
- Vitamine B complexe 50 VIT'ALL+, comprimé, withdrawn from the market
- Vitamines B gélule, withdrawn from the market
- Vitamines B gélule, withdrawn from the market
- Vitamines B Complex Linkednutri, autre : flacon-pompe airless, withdrawn from the market
- Vitamines B Libération prolongée Yves Ponroy, comprimé, withdrawn from the market
- Vitamines et Minéraux D.Plantes, gélule, withdrawn from the market
- Vitamines et Minéraux gélule, withdrawn from the market
- Vitamines grossesse gélule, withdrawn from the market
- VitascorbolImmuno+ sachet, withdrawn from the market
- Vitastrong Vitamin B COMPLEX capsule, withdrawn from the market
- Vétyane Équilibre Vétyane, gélule, withdrawn from the market
- WOMEN'S MULTIVITAMINS & MINERALS comprimé, withdrawn from the market
- WOMENS IMMUNE HEALTH NUTRIMUSCLE, gélule, flavour nature, withdrawn from the market
- WOMEN’S CARE HSN, comprimé, withdrawn from the market
- Wellness Minceur Triple Actions comprimé, withdrawn from the market
- X Pump poudre, flavour fruits des bois, withdrawn from the market
- X-Boost PROZIS, poudre, flavour agrumes, withdrawn from the market
- X-Boost PROZIS, poudre, flavour fruits des bois, withdrawn from the market
- X-Boost PROZIS, poudre, flavour cola, withdrawn from the market
- XENIUM CORGENIC, flacon, flavour wild berry blast, withdrawn from the market
- XS / Minceur autre : sachet + 2 gélules de formules différentes, withdrawn from the market
- XTrazec comprimé, withdrawn from the market
- Xcess Afterhours Xcore Series PROZIS, capsule, withdrawn from the market
- Xcess Afterhours Xcore Series PROZIS, capsule, withdrawn from the market
- ZENIREL Laboratoire Santarel, gélule, withdrawn from the market
- ZENIREL Santarel, gélule, withdrawn from the market
- ZERO FAT capsule, withdrawn from the market
- ZINC COMPLEXE gélule, withdrawn from the market
- ZINC PLUS LIQUID STAR WELL, flacon, flavour orange, withdrawn from the market
- ZMB ENERGY gélule, withdrawn from the market
- ZMB ENERGY gélule, withdrawn from the market
- ZN10+5 D-LAB Nutricosmetics, gélule, withdrawn from the market
- Zenirel Santarel, gélule, withdrawn from the market
- Zinc+ flacon, withdrawn from the market
- anti agium physionat, gélule, withdrawn from the market
- cholecontrol physionat, gélule, withdrawn from the market
- entero protect physionat, gélule, withdrawn from the market
- fertilité gélule, withdrawn from the market
- immunium physionat, gélule, withdrawn from the market
- multi vitamines junior comprimé, withdrawn from the market
- multi vitamines junior comprimé, withdrawn from the market
- multi vitamines junior comprimé, withdrawn from the market
- nu VITAMIN' NUTRITING, gélule, withdrawn from the market
- nutrisom nutrisom, comprimé, withdrawn from the market
- onday onday, poudre, flavour ananas / vanille, withdrawn from the market
- safrania 5-HTP gélule, withdrawn from the market
- synergium omega 3 physionat, gélule, withdrawn from the market
- synergium omega 6 physionat, gélule, withdrawn from the market
- visagelit gélule, withdrawn from the market
- vitalité retrouvée Comptoir Botanique, gélule, withdrawn from the market