Nicotinamide (vitamin B3) in food supplements
8,647 supplements declared in France contain a form of this nutrient
Nicotinamide: in France, a food supplement may not provide more than 54 mg a day (Order of 9 May 2006, not revised since November 2006, Annex III); for adults, EFSA's upper safe limit is 900 mg a day. The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Written Question No 2686, ministry answer published in the Official Journal on 11 February 2025.
What we know about this ingredient
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT04844528 : Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia With History of Non-melanoma Skin Cancers
RECRUITING · PHASE2 · Chronic Lymphocytic Leukemia, Non-melanoma Skin Cancer (NMSC) · 2025-12-03 · Nicotinamide
- NCT07585006 : Comparative Evaluation of Nicotine Analogs
RECRUITING · PHASE1 · Tobacco-Related Carcinoma, Addiction · 2026-06-26 · nicotinamide
- NCT07808333 : Nicotinamide for Retinal Protection in Primary Open-Angle Glaucoma (NADIR Trial)
NOT_YET_RECRUITING · PHASE2 · Glaucoma, Open-angle, Primary Open Angle Glaucoma (POAG) · 2026-10-13 · Nicotinamide
2026-11-01
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (nicotinamide (vitamine B3)) : sport (1112 produits), immunité (1052 produits), système nerveux (761 produits), cheveux et ongles (735 produits), peau (695 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
Jusqu'où c'est sûr
Pour un adulte, l'EFSAEuropean Food Safety Authority. fixe la limite supérieure de sécurité à 900 mg/j : c'est l'apport quotidien qui, pris sur le long terme, toutes sources alimentaires réunies, ne devrait pas provoquer d'effet indésirable. Au-delà, le risque augmente. Un complément n'est qu'une partie de l'apport.
EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
La règle en France
En France, la dose journalière recommandée d'un complément ne doit pas apporter plus de 54 mg (arrêté du 9 mai 2006, non révisé depuis novembre 2006). Compl'Alim ne publie pas la dose des produits déclarés : comparez celle de l'étiquette à ce plafond et à la limite de sécurité de l'EFSA.
French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
EFSA safety references
Le repère de l'EFSA porte sur l'apport total d'une journée, alimentation et compléments.
| Population | Type | Value |
|---|---|---|
| 1-3 years | Upper limit | 150 mg/j |
| 4-6 years | Upper limit | 220 mg/j |
| 7-10 years | Upper limit | 350 mg/j |
| 11-14 years | Upper limit | 500 mg/j |
| 15-17 years | Upper limit | 700 mg/j |
| adults | Upper limit | 900 mg/j |
| pregnancy | Upper limit | inadequate data |
| breastfeeding | Upper limit | inadequate data |
SCF, 2002a. EFSA, Overview on Tolerable Upper Intake Levels (version 11, August 2025), retrieved 21 October 2026.
Maximum dose in France
Maximum daily dose per supplement in France: 54 mg, according to the Order of 9 May 2006.
The doses of the 2006 Order have not been revised since the amending Order of 14 November 2006, and some were annulled by the Conseil d'État in 2011; the DGCCRF accepted higher levels for some nutrients through guidelines published until January 2019, and an update of the Order is being prepared (ministerial answer published in the Official Journal on 11 February 2025).
Order of 9 May 2006, Annex III. French orders of 9 May 2006 and 14 November 2006 as published in the Official Journal (maximum daily doses), retrieved 21 October 2026.
Forms declared in supplements
Union list: vitamin and mineral forms that may be used in a food supplement (Directive 2002/46/EC, Annex II).
Directive 2002/46/EC on food supplements, latest consolidated version (Annex II: forms of vitamins and minerals), retrieved 23 October 2026.
- Nicotinamide 8,534 products on the Union list
- Chlorure de nicotinamide riboside 135 products on the Union list
In cosmetics: NIACINAMIDE.
Products containing it
- UN PAR JOUR ALPHA KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UN PAR JOUR AVEC FER KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UN PAR JOUR AVEC FER BiOrganic Nutrition, comprimé, withdrawn from the market
- UN PAR JOUR FEMMES + 50 KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UN PAR JOUR PLUS AVEC FER KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UN PAR JOUR PLUS AVEC FER BiOrganic Nutrition, comprimé, withdrawn from the market
- UN PAR JOUR PLUS SANS FER KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UN PAR JOUR PLUS SANS FER BiOrganic Nutrition, comprimé, withdrawn from the market
- UN PAR JOUR SANS FER KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UN PAR JOUR SANS FER BiOrganic Nutrition, comprimé, withdrawn from the market
- UNSTRESS KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- UNSTRESS BiOrganic Nutrition, comprimé, withdrawn from the market
- UltraDyn® Impact poudre, flavour goût pêche-mangue, withdrawn from the market
- Ultraguts poudre, withdrawn from the market
- Under pressure BIRDIE, gélule, withdrawn from the market
- VENOM FULL STRENGHT LIFE PRO, poudre, flavour fruit punch, withdrawn from the market
- VENTRE-PLAT D-LAB NUTRICOSMETICS, gélule, withdrawn from the market
- VIALIS PRO PILLS gélule, withdrawn from the market
- VIBOVIT ABC VIBOVIT, gomme à mâcher, flavour fruits, withdrawn from the market
- VIBOVIT ABC VIBOVIT, gomme, flavour fruits, withdrawn from the market
- VIBOVIT AQUA VIBOVIT, gomme à mâcher, flavour fruits, withdrawn from the market
- VIBOVIT AQUA VIBOVIT, gomme, flavour fruits, withdrawn from the market
- VIBOVIT DINO VIBOVIT, gomme, flavour fruits, withdrawn from the market
- VITA-MIN MULTIPLE SHOT OLIMP SPORT NUTRITION, ampoule, flavour citrus punch, withdrawn from the market
- VITAL GUM MEDISENS, gomme à mâcher, withdrawn from the market
- VITAL PERFORMANCE POST poudre, flavour yuzu clementine, withdrawn from the market
- VITAL PERFORMANCE POST poudre, flavour lemon grape, withdrawn from the market
- VITAL PERFORMANCE POST poudre, flavour watermelon berry, withdrawn from the market
- VITALFAN ANTICHUTE PROGRESSIVE RENE FURTERER, capsule, withdrawn from the market
- VITALINOV EFFINOV NUTRITION, gélule, withdrawn from the market
- VITALITE BOOST comprimé, flavour acerola, withdrawn from the market
- VITALITE BOOST MEDIEXPERT, gélule, withdrawn from the market
- VITALITYBOOST Boticinal Laboratoire, comprimé, withdrawn from the market
- VITALITÉ Nut'excel, sirop, withdrawn from the market
- VITAMIN B IO GENIX, comprimé, withdrawn from the market
- VITAMIN B-COMPLEX WITH VITAMIN D3 comprimé, withdrawn from the market
- VITAMIN B3 500 MG NICOTINAMIDE HSN, capsule, withdrawn from the market
- VITAMINE B - COMPLEX ORGANIQUE FORTE SINGULARIS Superior capsule, withdrawn from the market
- VITAMINERIS BOOST GRANIONS, sachet, flavour pomme, withdrawn from the market
- VITAMINERIS BOOST 1000 mG GRANIONS, sachet, flavour pomme, withdrawn from the market
- VITAMINERIS SENIOR 1000 mg GRANIONS, comprimé, flavour cassis, withdrawn from the market
- VITAMINES B COMPLEX KARIKAS ORTHOMOLECULAR NUTRITION, comprimé, withdrawn from the market
- VITAMINES B COMPLEX BIORGANIC NUTRITION, comprimé, withdrawn from the market
- VITAMINES ET MINERAUX gélule, withdrawn from the market
- VITAMINES MINÉRAUX PHARMATECH, gélule, withdrawn from the market
- VITAMINO+ ERIC FAVRE SANTE, comprimé, withdrawn from the market
- VITAREL + Laboratoire Santarel, gélule, withdrawn from the market
- VITASCORBOL DEFENSE sachet, flavour orange, withdrawn from the market
- VM gélule, withdrawn from the market
- Valedia comprimé comprimé, withdrawn from the market
- Valedia stick bâton / batônnet / stick, withdrawn from the market
- Veino'Action Expert comprimé, withdrawn from the market
- Vinaigre MOROSIL SYSNAT, flacon, withdrawn from the market
- Visiobiane confort capsule, withdrawn from the market
- Vit Min First Iron Systems, gélule, withdrawn from the market
- VitaBoost LUUME, comprimé, withdrawn from the market
- Vitaboost gélule, withdrawn from the market
- Vitacor Plus Drink Dr. Rath, poudre, withdrawn from the market
- Vital'18 Strapharm, gélule, withdrawn from the market
- Vitaldin Multivitamin Gummies Vitaldin, gomme, withdrawn from the market