Curcumine in food supplements

163 supplements declared in France contain Curcumine as a substance or active ingredient.

Other names in the Compl'Alim list: curcumin.

Uses

• Analytical reagent, food dye, biological stain. As an acid-base indicator it is brownish-red with alkalies, yellow with acids (pH range 7.4-8.6); also as an indicator for boron.

• Curcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as antioxidant activity, inducing cell apoptosis, inhibiting cell proliferation, anti-cell adhesion and motility, anti-angiogenesis and anti-microbe properties. Based on these functions, curcumin has been used in clinical trials on various inflammatory diseases and cancers. In the future, it will be necessary to focus attention partly on the clinical application of curcumin in neurodegenerative diseases, cardiovascular diseases and diabetes, because many experiments have clarified the potential value of curcumin in these areas...

• Flavoring and coloring agent in food-as turmeric; boron indicator; stain in microscopy; alkali indicator; coloring agent for oils, waxes, & textiles

• For preparing curcuma paper, pH range 8-9. In the detection of boron.

Use classification

• Food additives

• Cosmetics -> Cosmetic colorant

A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.

Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).

Natural occurrence recorded in Wikidata (LOTUS database): 29 taxa; examples: Curcuma longa, Curcuma zedoaria, Zingiber officinale, Zingiber cassumunar, Glycyrrhiza glabra.

Manufacturing

• Occurs naturally in the root of the herb curcuma longa (turmeric); isolation by steam distillation

• Production: Stieglitz, Horn, German patent 859145 (1952 to Hoechst)

• The essential oil of Curcuma longa is obtained by steam distillation, with yields ranging between 1.3 and 5.5%. ... The oil contains, in addition to turmerone (~60%), free acids, cineol, borneol, zingerone, phellandrene, and 3 to 4% coloring matter (curcumin). /Essential oil of Curcuma longa/

Appearance

• Orange yellow prisms, rhombic prisms from methanol

• Orange-yellow needles

• Orange-yellow, crystal powder; gives brownish-red color with alkali; light-yellow color with acids

• Curcumin appears as orange-yellow needles. (NTP, 1992)

• Orange-yellow crystalline powder

Stability

• Orange-yellow turmeric will hold shade better than lemon-yellow when exposed directly or indirectly to sunlight /turmeric/

• Stable under recommended storage conditions.

Novel food catalogue (European Union), entry “Curcumin”, part “Whole” only: Classé par le catalogue comme nouvel aliment non encore autorisé : sous la forme visée par l'entrée, il ne devrait pas être vendu dans l'Union tant qu'il n'est pas autorisé. Le catalogue est informatif ; une déclaration en France (« commercialisation possible ») n'est pas une autorisation.

Health claims register (European Union): 0 authorised and 1 refused claim(s) for this substance.

Compl'Alim ingredient list (France): listed.

Canada, licensed natural health products (LNHPD): 14 products.

United States, supplement labels (DSLD; supplements need no prior approval): 272 products.

Japan, notified foods with function claims: 37 products.

Poland, notified supplements: 2 products.