Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- Amino Prime Caffeine Free Prozis, poudre, flavour cola, declared in 2020
- Amino Slim Be Health, comprimé, declared in 2026
- Amino Tabs comprimé, declared in 2023
- Amino fast poudre, flavour framboise bleue, declared in 2020
- Amino fast poudre, flavour fraise banane, declared in 2020
- Amino-360 BIOVANCIA, comprimé, declared in 2026
- Amino-9 Essentials, Powder NOW Foods, poudre, declared in 2025
- Aminobolan Sanas, ampoule, declared in 2022
- Aminoday flacon, declared in 2023
- Aminoday Extreme flacon, declared in 2022
- Aminosäuren Vital gélule, declared in 2026
- Amix™ GH gélule, declared in 2025
- Amix™ Yeep Muscle Pump™ (Giant lime shock) Amix™, poudre, flavour giant lime shock, declared in 2025
- Amix™ Yeep Muscle Pump™ (Orange attack) Amix™, poudre, flavour orange attack, declared in 2025
- AndroKare MEDIKAREPRO, gélule, declared in 2022
- Applied Nutrition Amino Fuel Applied Nutrition, poudre, declared in 2026
- Arthrol Vitality Nutritionals, gélule, declared in 2021
- BCAA 2.1.1 - Lysine & Glutamin Vegan poudre, flavour cola, declared in 2018
- BCAA 4.1.1 enrichis en EAA poudre, flavour fruits rouges, declared in 2023
- BCAA 4.1.1 enrichis en EAA poudre, flavour pêche, declared in 2023
- BCAA 4.1.1 enrichis en EAA poudre, flavour citron, declared in 2024
- BIG BANG 3.0 SCITEC NUTRITION, poudre, flavour orange, declared in 2016
- BIG BANG 3.0 SCITEC NUTRITION, poudre, flavour mangue, declared in 2016
- BIO-ELIXIR sachet, declared in 2026
- BIONATURE - INCREDIBLE HAIR comprimé, declared in 2024
- BIOTINE POUR LES CHEVEUX Kivée Labs, capsule, declared in 2022
- BOMBI YAM NUTRITION, poudre, flavour pêche, declared in 2025
- BOOST YOUR HAIR American Liss, gélule, declared in 2025
- BSc EAA+ BSc, poudre, flavour elderflower, declared in 2025
- BSc EAA+ BSc, poudre, flavour watermelon, declared in 2025
- Balance low lactose protein - Chocolat NUTRIMSUCLE, poudre, flavour chocolat, declared in 2024
- Balance low lactose protein - Cookie Nutrimuscle, poudre, flavour choco-cookie, declared in 2024
- Bcaa eaa 12.1.1 Nutritional performance labs npl, poudre, flavour fraise kiwi, declared in 2026
- Be Recharged Berry Lifeplus, poudre, declared in 2026
- Be Recharged Citrus Lifeplus, poudre, declared in 2026
- Be recharged 3 poudre, flavour agrumes, declared in 2017
- Be recharged 3 poudre, flavour fruits rouges, declared in 2017
- Beauty Skin Be-Life, gélule, declared in 2017
- Bedtime Shake Protein Powder poudre, flavour chocolate, declared in 2023
- Bedtime Shake Protein Powder poudre, flavour strawberry, declared in 2023
- Beef&Egg Amino – GymBeam - 500 comprimés GymBeam, comprimé, declared in 2026
- Better Skin from Within Skinade, flacon, declared in 2025
- Bien Être Articulaire Laboratoire Activa, gélule, declared in 2024
- Bien Être Détox Laboratoire Activa, gélule, declared in 2022
- Bien Être Inflalyse Laboratoire Activa, gélule, declared in 2024
- Big Shot - Intra-Workout PROZIS, poudre, flavour pomme verte fraîche, declared in 2021
- Big Shot - Intra-Workout PROZIS, poudre, flavour flash cola, declared in 2021
- Big Shot - Intra-Workout Prozis, poudre, flavour neutre, declared in 2021
- Big Shot - Intra-Workout Prozis, poudre, flavour poire mure, declared in 2021
- Big Shot - Intra-Workout Prozis, poudre, flavour limonade rosée, declared in 2021
- Big Shot - Recovery Prozis, poudre, flavour explosion de fruit, declared in 2021
- Big Shot Recovery PROZIS, poudre, flavour explosion de fruit, declared in 2025
- Blossom Indiba, flacon, declared in 2024
- Bombi Chrisbody, poudre, flavour orange, declared in 2018
- Bone Broth, Beef Powder NOW Foods, poudre, declared in 2025
- Booster de Collagène Vegan D-LAB POSITIVE, gélule, declared in 2025
- CALCIUM, MAGNESIUM, ZINC, VITAMINES, LYSINE sirop, declared in 2023
- CAPIL FORTÉ CHEVEUX Vitaminal, gélule, declared in 2026
- CAPILASE gélule, declared in 2022
- CAPactifs Laboratoires SYNActifs, gélule, declared in 2025
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- Women's Advanced Protein Vanilla Ice Cream Supplement from the US market
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- Precision Amino Gummy Worm Supplement from the US market
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- Precision Amino Peach Mango Tea Supplement from the US market
- Amino-Pro Supplement from the US market
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- Caprotein Supplement from the US market
- Accell Meal Complete Superfruit Supplement from the US market
- Eventa LQ Supplement from the US market
- Time C Timed Release With Magnesium And Lysine 1000 Supplement from the US market
- Plant Protein 21 g Banana Supplement from the US market
- Advanced Collagen Peptides Unflavored Supplement from the US market
- Vegan Complete Vanilla Supplement from the US market
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- EAAs Essential Amino Acids Watermelon : étiquette retirée du marché américain Supplement from the US market
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- Raw Organic 100% Plant-Based Protein Very Berry Supplement from the US market
- Raw Organic 100% Plant-Based Protein French Vanilla Supplement from the US market
- Vegan Organic All in One Nutritional Shake French Vanilla Supplement from the US market
- Vegan Organic All in One Nutritional Shake Decadent Chocolate Supplement from the US market
- Protein & Greens Organic Vanilla Chai Supplement from the US market
- Protein & Greens Unflavored Supplement from the US market
- Prevail Vegan Protein Vanilla : étiquette retirée du marché américain Supplement from the US market
- Prevail Vegan Protein Chocolate : étiquette retirée du marché américain Supplement from the US market
- Prevail Whey Protein-Blend Chocolate : étiquette retirée du marché américain Supplement from the US market
- Prevail Vanilla : étiquette retirée du marché américain Supplement from the US market
- VegaLite Chocolate : étiquette retirée du marché américain Supplement from the US market
- VegaLite Vanilla : étiquette retirée du marché américain Supplement from the US market
- Whey Protein Isolate Chocolate : étiquette retirée du marché américain Supplement from the US market
- Whey Protein Isolate Vanilla : étiquette retirée du marché américain Supplement from the US market
- Whey Protein Isolate Chocolate : étiquette retirée du marché américain Supplement from the US market
- Whey Protein Isolate Vanilla : étiquette retirée du marché américain Supplement from the US market
- Combat Protein Powder Chocolate Milk Supplement from the US market
- Natural Whey Protein Concentrate : étiquette retirée du marché américain Supplement from the US market
- Combat Powder Triple Berry Supplement from the US market
- Forti-Flax : étiquette retirée du marché américain Supplement from the US market
- Organic Forti-Flax Supplement from the US market
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- Flax- Chia- Coconut : étiquette retirée du marché américain Supplement from the US market
- Longer, Stronger Hair and Nails Supplement from the US market