Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- CAPactifs intense gélule, declared in 2023
- CHEVEUX ALMIYANA, gélule, declared in 2024
- CHEVEUX POUSSE Clinivita, gélule, declared in 2025
- CHEVEUX force et pousse DEFI FORME, gélule, declared in 2026
- CLEARPEA® PROTEIN (CHERRY) GEN® GERMAN ELITE NUTRITION, poudre, flavour cerise, declared in 2025
- CLEARPEA® PROTEIN (COLA) GEN® GERMAN ELITE NUTRITION, poudre, flavour cola., declared in 2025
- CLEARPEA® PROTEIN (GREEN APPLE) GEN® GERMAN ELITE NUTRITION, poudre, flavour pomme verte, declared in 2025
- CLEARPEA® PROTEIN (HONEYDEW MELON) GEN® GERMAN ELITE NUTRITION, poudre, flavour melon miel, declared in 2025
- CLEARPEA® PROTEIN (ICE TEA) GEN® GERMAN ELITE NUTRITION, poudre, flavour thé glacé à la pêche, declared in 2025
- CLEARPEA® PROTEIN (ORANGE) GEN® GERMAN ELITE NUTRITION, poudre, flavour jus d'orange, declared in 2025
- CLONAMASTER - NEUTRAL (+M) +M, poudre, declared in 2026
- COLLAGEN VEGAN BOOSTER flacon, declared in 2021
- COLLAGEN-LIFT-DRINK poudre, declared in 2018
- COLLAGENES GENESIS+ NUTRIZOE, sachet, flavour ananas, declared in 2025
- COLLAGÈNE BUILDER COMPLEXE D'ACIDES AMINÉS poudre, declared in 2026
- COLLAGÈNE BUILDER COMPLEXE D'ACIDES AMINÉS poudre, declared in 2025
- COLLAGÈNE BUILDER* COMPLEXE D’ACIDES AMINÉS poudre, declared in 2024
- COLLAGÈNE MARIN 10 GR ÉQUILIBRE PREMIUM poudre, declared in 2025
- COLLAGÈNE VEGAN KAYA, poudre, flavour orange, declared in 2023
- COLLAGÈNE VEGAN PÊCHE MANGUE KAYA, poudre, flavour pêche mangue, declared in 2024
- COMPLEMENT ALIMENTAIRE avec vitamine D3 10.000 I.U. et vitamine K2 200 µg Vitabay, comprimé, declared in 2026
- COMPLEX AMINO+ EQUI-NUTRI, gélule, declared in 2018
- COMPLEX CARNITINE XNOVA, gélule, declared in 2026
- COMPLEXE ACIDES AMINES FER gélule, declared in 2020
- COMPLEXE ACIDES AMINÉS DIETI NATURA, gélule, declared in 2025
- COMPLEXE DE FER 14 ULTRA gélule, declared in 2026
- COMPLEXE DE POUSSE D-LAB NUTRICOSMETICS, gélule, declared in 2023
- COMPLEXE K A LA SPIRULINE KALIA NATURE, gélule, declared in 2025
- COMPLEXE LIPO REDUCTEUR gélule, declared in 2023
- COMPLEXE LIPOREDUCTEUR PHYTALLIANCE, gélule, declared in 2020
- COMPLÉMENT ALIMENTAIRE avec vitamine K2. comprimé, declared in 2026
- COUP DE POUSSE NATISHA, gélule, declared in 2023
- CRAZY MINO poudre, declared in 2019
- CROISSANCE CHEVEUX N16 PROFESSIONNEL, gélule, declared in 2026
- Capi'UP gélule, declared in 2024
- Capilase gélule, declared in 2020
- Capilhair Capilhair, capsule, declared in 2016
- Cellergize Morning Cellergize, poudre, flavour citron et gingembre, declared in 2026
- Cheveux DEFI FORME, gélule, declared in 2022
- Cheveux gélule, declared in 2021
- Cheveux* Gommes Folly, gomme, flavour fruits tropicaux, declared in 2026
- Cheveux* Gommes Folly, gomme, flavour fruits tropicaux aigres, declared in 2026
- Chrono Inflalyse Laboratoire Activa, gélule, declared in 2025
- CogniMag+ NaturaMedicatrix, poudre, flavour aucun, declared in 2024
- Cognimag + gélule NATURAMedicatrix, gélule, declared in 2025
- Colla+ poudre, declared in 2025
- Collagen MCT poudre, declared in 2022
- Collagen Pro Vivana, sachet, declared in 2026
- Collagène poudre, declared in 2024
- Collagène Marin Type I poudre, declared in 2026
- Collagène Marin Type I, II, III & IV gélule, declared in 2026
- Collagène Marin Type I, II, III & IV 1Kg poudre, declared in 2026
- Collagène Marin en Poudre poudre, declared in 2026
- Collagène RAW (sans édulcorants) Crown Sport Nutrition, poudre, flavour sans arôme (neutre), declared in 2026
- Collagène marin gélule, declared in 2025
- Collagène marin + EAA KRC Nutrition, poudre, flavour ice tea pêche, declared in 2024
- Complex Carnitine FitnessBoutique, gélule, declared in 2018
- Complex'Nutri Nat&Form, gélule, declared in 2023
- Complexe Peau, Ongles Cheveux Onatera, gélule, declared in 2025
- Complexe de Pousse D-LAB NUTRICOSMETICS, gélule, declared in 2024
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