Lysine in food supplements
771 supplements declared in France contain Lysine as a substance or active ingredient.
Compl'Alim declarations. Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What we know about this ingredient
Uses
BIOLOGICAL ACTIVITIES: Antialkalotic; antiherpetic; essential; hypoarginanemic
Biochemical and nutritional research, pharmaceuticals, culture media, fortification of foods and feed (wheat flour), nutrient and dietary supplement, animal feed additive
Enrichment of cereals and feeds.
Medical use: treatment of hypochloremia, alkalosis /lysine hydrochloride/
Reported uses
Table: Reported uses (ppm): (Flavor and Extract Manufacturers' Association) [Table#3864]
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · USDA; Dr. Duke's Phytochemical and Ethnobotanical Databases. Plants with a chosen chemical. Lysine. Washington, DC: US Dept Agric, Agric Res Service. Available from, as of August 17, 2010: https://www.ars-grin.gov/duke/; Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977; Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 86 (1985); Burdock, G.A. (ed.). Fenaroli's Handbook of Flavor Ingredients. 6th ed.Boca Raton, FL 2010, p. 1110.
Use classification
Cosmetics -> Skin conditioning; Hair conditioning; Antistatic
A molecule found naturally in plants or organisms; in a supplement it may be extracted from them, made by fermentation or synthesised: the declaration does not say which.
Basis: one CosIngThe European Commission's database of cosmetic ingredients. CAS and natural occurrence recorded in Wikidata (LOTUS database).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Natural occurrence recorded in Wikidata (LOTUS database): 119 taxa; examples: Morchella angusticeps, Morchella crassipes, Citrus grandis, Citrus medica, Pinus densiflora.
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Manufacturing
A process combining chemical and microbiological techniques for the production of L-lysine was introduced by Toray Industries; /in this process/, alpha-amino-e-caprolactam (ACL) is formed from cyclohexanol... this intermediate is then hydrolyzed with L-ACL-hydrolase to yield L-lysine
Extraction of natural proteins, synthetically by fermentation of glucose or other carbohydrates and by synthesis from caprolactum
Isolation from acid-hydrolyzed proteins (casein, fibrin or blood corpuscle paste)
The usual raw material for the fermentation production of L-lysine is molasses...high performance microbes belong to the species Corynebacterium glutamicum or Brevibactrium lactofermentum
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Gerhartz, W. (exec ed.). Ullmann's Encyclopedia of Industrial Chemistry. 5th ed.Vol A1: Deerfield Beach, FL: VCH Publishers, 1985 to Present., p. VA2: 71 (1985); Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 887.
Appearance
Colorless crystals
Needles from water, hexagonal plates from dilute alcohol
PubChem : Hazardous Substances Data Bank (HSDB) · 2026-10-29 · Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 773; O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 2006., p. 977.
Taste described
Sweet/bitter
Associated research
ClinicalTrials.gov · A trial is not proof: it tests a hypothesis.
- NCT05210504 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 3
COMPLETED · PHASE1 · Diabetes Mellitus, Type 2 · 2024-06-05 · L-Lysine
- NCT06580145 : Leucine in Midlife Depression
RECRUITING · PHASE2 · Major Depression · 2026-09-11 · L-lysine; L-lysine (synonym declared in the registry)
- NCT04417218 : Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2
COMPLETED · NA · Healthy · 2023-12-21 · Lysine
2026-11-01
Other names: L-lysine (French), L-lysine (English).
Wikidata: names of substances in six languages and taxa in which they occur (largely from the LOTUS database), retrieved 23 October 2026.
Same substance in cosmetics: LYSINE.
In plain words
À quoi il sert, selon les fabricants
Objectifs les plus souvent annoncés pour les compléments qui en contiennent (Lysine) : sport (252 produits), cheveux et ongles (110 produits), peau (54 produits), articulations (42 produits), immunité (42 produits).
Ce sont les objectifs déclarés par les fabricants à l'administration, pas des effets démontrés. Sur l'emballage, seules les allégations de santé autorisées par l'Union peuvent être écrites.
Compl'Alim, food supplement declarations (France), retrieved 23 October 2026.
What the registers say, country by country
Each line repeats what an official register says on the date it was consulted. Not being in a register means neither allowed nor banned.
Health claims register (European Union): 0 authorised and 8 refused claim(s) for this substance.
EU Register of nutrition and health claims, retrieved 21 October 2026.
Compl'Alim ingredient list (France): listed.
Compl'Alim, reference list of ingredients, retrieved 21 October 2026.
Canada, licensed natural health products (LNHPD): 953 products.
Licensed Natural Health Products Database (LNHPD), Health Canada: licensed products, ingredients, doses, uses and risks, retrieved 27 October 2026.
Contains information licensed under the Open Government Licence – Canada (Health Canada, LNHPD)
Licence du gouvernement ouvert – Canada 2.0 (OGL-Canada 2.0)
United States, supplement labels (DSLD; supplements need no prior approval): 1330 products.
Dietary Supplement Label Database (DSLD), US National Institutes of Health: current and off-market labels, retrieved 27 October 2026.
Source: NIH Office of Dietary Supplements, Dietary Supplement Label Database (CC0); US market labels.
Declared daily quantities
| Unit | Products | Median | Minimum | Maximum |
|---|---|---|---|---|
| mg | 133 | 480 | 0.009 | 7,400 |
Calculated from Compl'Alim declarations that provide a quantity. These are quantities declared by manufacturers, not measurements, and preparation is not distinguished (powder, extract of varying concentration): differences between products can be very large.
Products
- POUSSE Cheveux LM NUTRI, gélule, declared in 2022
- POUSSEE D'AMOUR BEAUTE INSOLENTE, gélule, declared in 2024
- PRE WORKOUT poudre, flavour blue tropic, declared in 2017
- PRE WORKOUT poudre, flavour citron vert-citron, declared in 2017
- PRISE DE POIDS GUMMIES femmes et hommes gomme à mâcher, declared in 2025
- PRO KERACYS CHEVEUX KERATINE 1000 mg GRANIONS, comprimé, declared in 2025
- PROLINE LYSINE gélule, declared in 2018
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS poudre, flavour texas tea, declared in 2024
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS poudre, flavour blue raspberry, declared in 2024
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS poudre, flavour blackberry - lemonade, declared in 2024
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS Fruit Punch poudre, flavour fruit punch, declared in 2024
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS Grape poudre, flavour raisins, declared in 2025
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS Mango poudre, flavour mangue, declared in 2024
- PROSUPPS - HYDRO BCAA PLUS ESSENTIALS Watermelon poudre, flavour pastèque, declared in 2024
- PURE EAA XL LAB, poudre, flavour apple, declared in 2020
- PURE EAA XL LAB, poudre, flavour cherry, declared in 2020
- PURE MULTIVITAMINE capsule, declared in 2022
- PURE PROFESSIONAL - ESSENTIAL AMINO Poudre (Saveur citron) TSUNAMI NUTRITION, poudre, flavour citron, declared in 2025
- PURE PROFESSIONAL - ESSENTIAL AMINO Poudre (Saveur pêche) TSUNAMI NUTRITION, poudre, flavour pêche, declared in 2025
- PURE PROFESSIONAL - GLYCO PURE poudre, flavour thé pêche, declared in 2024
- PURE PROFESSIONAL - GLYCO PURE poudre, flavour melon d'eau, declared in 2024
- PURE PROFESSIONAL - GLYCO PURE poudre, flavour strawberry lemonade, declared in 2024
- PURE PROFESSIONAL - GLYCO PURE poudre, flavour neutre, declared in 2024
- PURE PROFESSIONAL - GLYCO PURE poudre, flavour fruit punch, declared in 2024
- PURE PROFESSIONAL - NITROPURE gélule, declared in 2025
- PharmGrade EAA poudre, declared in 2019
- Physiocap VITAVEA - Laboratoires Yves Ponroy, gélule, declared in 2025
- Pianto Agrumes Pianto, flacon, declared in 2026
- Pianto Agrumes Pianto, flacon, declared in 2025
- Pianto Agrumes Pianto, flacon, declared in 2021
- Pianto Classic Pianto, flacon, declared in 2026
- Pianto Classic Pianto, flacon, declared in 2023
- Pousse et Fortification Cheveux LF, gélule, declared in 2026
- Premium EAA Tropical Weider, poudre, flavour tropical, declared in 2025
- Proline Lysine gélule, declared in 2018
- Prosta Plant Vitalplant, gélule, declared in 2026
- Proteatonic Laboratoire Activa, gélule, declared in 2021
- Protéine de lactosérum au Cookies de qualité supérieure - 1 000 g NŪMYA, poudre, flavour cookies, declared in 2026
- Protéine de lactosérum premium à la fraise - 1000 g NŪMYA, poudre, flavour fraise, declared in 2026
- Protéine de lactosérum premium à la vanille - 1 000 g NŪMYA, poudre, flavour vanille, declared in 2026
- Protéines de lactosérum premium au chocolat - 1000 g NŪMYA, poudre, flavour chocolat, declared in 2026
- Pure Whey 100% My Performance Overall Athletica, poudre, flavour french cream vanilla, declared in 2026
- RACINE PLUS gélule, flavour /, declared in 2026
- RBC FORCE MAX 3C PHARMA, comprimé, declared in 2019
- REGENER 8 gélule, declared in 2024
- REGENER-8 NUTRISOLUTION, gélule, declared in 2020
- RENEW poudre, flavour kiwi et fruits des bois, declared in 2024
- REVITYL ampoule, declared in 2022
- RINGANA bty Ringana, flacon, declared in 2025
- ROYAL JELLY SENIOR VITALITY flacon, declared in 2021
- RPS - Lysine Echinacée Zinc well&well, comprimé, declared in 2016
- RTP - EAA comprimé, declared in 2026
- Radiance ASEA, bâton / batônnet / stick, declared in 2024
- Regenum Lorica, bâton / batônnet / stick, flavour agrumes, declared in 2024
- Renew poudre, declared in 2022
- Régénum pot Lorica, poudre, flavour pêche, declared in 2026
- SERENITE comprimé, declared in 2025
- SPECIAL KID SIROP MULTIVITAMINES sirop, declared in 2023
- STACKER2 EUROPE - ESSENTIAL AMINOS Blue Raspberry STACKER2 EUROPE, poudre, flavour blue raspberry, declared in 2026
- STACKER2 EUROPE - ESSENTIAL AMINOS Orange STACKER2 EUROPE, poudre, flavour orange, declared in 2026